AU2009202123A1 - Aerosol Moisturiser - Google Patents

Description

AUSTRALIA Patents Act 1990 COMPLETE SPECIFICATION Standard Patent Applicant(s): ENSIGN LABORATORIES PTY LTD Invention Title: Aerosol Moisturiser The following statement is a full description of this invention, including the best method for performing it known to me/us: P71901.AU.2 PalSet_Filing Application 2009-5-25.doc (M) - 2 MOISTURISER FIELD OF THE INVENTION s The present invention relates to moisturisers. In one form the moisturisers are low oil phase moisturisers in which the moisturiser contains a reduced or low amount of oil. 10 In another form, the present invention relates to pressurised aerosol dispensers for dispensing moisturisers, particularly low oil phase moisturisers. 15 In another form, the present invention relates to moisturisers having a cooling effect on the skin when applied to the skin, particularly for a short period of time immediately after application of the moisturizer to the skin. 20 The present invention finds particular application as a moisturiser composition that can be dispensed from an aerosol container as fine droplets in the form of a fine spray or mist to provide contactless application of the 25 moisturiser to the skin to provide a substantially uniform coverage of moisturiser over the surface of the skin. Although the present invention will be described with particular reference to one form of the moisturiser it is 30 to be noted that the present invention is not restricted to the described embodiment but rather the scope of the present invention is more extensive so as to include other formulations of the moisturiser composition, other N:\Melboume\Cases\Patent\710O0-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11 doc 28/05/09 - 3 containers for containing and dispensing the moisturiser composition and other uses of the various formulations. BACKGROUND OF THE INVENTION 5 Existing moisturisers are available in a number of different forms. Some of the more commonly available forms include creams, lotions, gels or similar that must be applied to the skin and body by contact with the skin io and body such as for example, contact by rubbing or working the cream, lotion or gel etc. into the skin using the hand or other implement such as an applicator to spread the lotion over the skin so as to allow the active ingredients of the moisturiser to be absorbed onto, into is and through the skin so as to provide the beneficial effect of the moisturiser, i.e. a moisturising effect, for the skin and body generally. In many situations, rubbing the cream, lotion or gel etc. into the skin is not practicable, such as for example, when the skin is subject 20 to a painful skin condition such as inflammation, redness, sunburn, injury, rash, dermatitis or other skin condition, or the like. Additionally, if an applicator is used and the skin 25 condition is contagious having a risk of cross infection, the applicator needs to be sterilised before reuse or discarded after a single use, which reduces the usefulness of using the applicator. 30 Often it is painful to apply and rub creams and lotions into the skin when applying moisturiser to achieve an amelioration of the adverse effects of the condition of the skin such as for example to remove heat from the skin N:\Melboume\Casos\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28105109 -4 after sunburn has occurred. Therefore, there is a need for a moisturiser composition in a form that can be applied to the skin in an essentially contactless manner that does not require the moisturiser to be rubbed or 5 otherwise worked into the skin after it has been applied to the skin either by hand or using an implement or applicator. There is also a need for a method of application of a 10 moisturiser to the skin which overcomes the need to use some other means of applying the moisturiser to the skin such as for example, using a hand, implement, applicator or similar, by being able to apply the moisturiser directly to the skin in a form that covers the area of is skin sufficiently to be effective without having to rub the moisturiser into the skin. Another problem associated with many existing moisturisers is that the moisturiser compositions are restricted to 20 having a moisturising effect only and do not have additional other beneficial effects other than moisturising the skin, such as for example by being therapeutic or the like, including by providing temporary pain relief or temporary cooling or the like to the skin 25 to which the moisturiser has been applied. Thus, there is a need to provide a moisturiser having at least one beneficial effect other than moisturising to the skin when applied and to methods of delivery or dispensing the moisturiser, such as for example, methods of applying the 30 moisturiser, in which the moisturiser has beneficial effects. N:\MeIboume\Cases\Paten\71000-71999\P71901 AU 2\Specis\P71901 AU 2 Specification 2009-5-11 doc 28/05/09 - 5 Accordingly, it is one aim of the present invention to provide a moisturiser or moisturiser composition or moisturiser containing material which can be dispensed from a suitable container or dispenser directly onto the 5 skin of a person without having to spread or otherwise work the moisturiser into the skin to obtain coverage of the skin by the moisturiser and to obtain a moisturising effect either alone or in combination with at least one other effect. 10 It is another aim of the present invention to provide a method of dispensing a moisturiser which allows the moisturiser to be applied directly to the skin without having to spread the moisturiser over the surface of the 15 skin, such as for example, being able to directly apply the moisturiser to the skin without having to rub the moisturiser into the skin to achieve coverage of the skin or without having to use an applicator in direct contact with the skin. 20 SUMMARY OF THE INVENTION According to one aspect of the present invention there is provided a moisturiser composition capable of being 25 dispensed from a pressurised container in the form of droplets of the moisturiser composition for direct application to the skin of a person suffering from a skin condition to provide a substantially uniform coverage of the moisturiser over the skin without the need to 30 additionally distribute the moisturiser over the skin. According to another aspect of the present invention there is provided an aerosol dispenser containing a moisturiser N \Melboume\Cases\Patent\71000-71999\P71901 AU 2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 6 composition or a moisturiser containing composition in which the moisturiser composition can be dispensed from the dispenser in the form of droplets of the moisturiser composition for direct application to the skin of a person 5 suffering from a skin condition requiring alleviation by contact with the moisturiser composition to provide a uniform coverage of the moisturiser composition over the skin to provide a moisturising effect to the skin wherein after the moisturiser composition is applied, there is no 10 need to additionally distribute the moisturiser composition in contact with the skin to effect the substantially uniform coverage. According to another aspect of the present invention there 15 is provided a moisturiser composition capable of being dispensed from an aerosol container the moisturiser composition comprising from about 1 to about 99% by weight of an emulsion composition and from about 99% to about 1% by weight of a propellant composition in which the 20 emulsion composition includes at least one moisturiser or moisturising agent and the propellant is at least in part dimethyl ether, said moisturiser composition being dispensed from the aerosol container in the form of fine droplets to provide a substantially uniform coverage of 25 the moisturiser composition over the skin to which the composition is applied thereby providing at least a moisturising effect to the skin without the need to additionally distribute the moisturiser composition over the skin after the moisturiser is applied to the skin to 30 provide uniform coverage. N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU 2 Specification 2009-5-11 doc 28105/09 - 7 BRIEF DESCRIPTION OF THE INVENTION It is to be noted that the term moisturiser or moisturiser composition used in the present specification includes s within the meaning and scope of this term, substances such as moisturiser, moisturising agent, moisturiser composition, moisturiser containing composition and the like. The term moisturiser is used for clarity of expression and ease of understanding. 10 Typically, the moisturiser or moisturising agent or moisturiser composition, or moisturizer containing composition has a low oil content. More typically the moisturiser composition is a low oil phase composition, is more particularly the moisturiser contains a very low oil phase component. Oils are generally regarded as materials which are anhydrous and insoluble in water. Such materials can be converted to being soluble in water by the addition of a suitable emulsifier. 20 Preferably, the amount of oil in the composition is less than about 20% by weight, preferably, less than about 10% by weight, more preferably less than about 5% by weight, even more preferably less than about 3% by weight, and 25 most preferably from about 1-2% by weight. Typical oils include aliphatic hydrocarbons, esters, mineral based oils, synthetic oils, waxes, derivatives of oils, silicones, and similar materials. 30 Typically, the moisturiser allows contactless application to the skin or body of the person to which the moisturiser is applied. By "contactless application" it is meant that N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901 AU.2 Specification 2009-5-11 doc 28/05109 - 8 the moisturiser composition is applied directly to the skin from the dispenser, such as by spraying directly from the dispenser which is usually an aerosol composition, but could include a pump action container in some s circumstances, onto the skin, without the need to additionally distribute the composition over the skin after the composition is applied to the skin by the aerosol container, such as for example without having to rub or work the moisturiser into the skin to achieve a 10 uniform coverage of the skin, such as by spreading the moisturiser composition by hand or using an implement, spreader or similar. More typically, the moisturiser provides a therapeutic, 15 pharmaceutical, dermatological, physiological, psychological or other effect on the skin of the person. Typically, the moisturiser provides relief from pain. More typically, the application of the moisturiser to the skin or body of the person suffering from the skin 20 condition provides relief from the skin condition for at least a few minutes after the moisturiser has been applied. Even more typically, the application of the moisturiser produces a cooling effect on the skin, particularly a temporary cooling effect immediately after 25 application. It is to be noted that the relief from the skin condition can be a real relief or it can be an apparent or imagined relief such as for example, a suggestion of relief. A particularly preferred application of the moisturiser of the present invention is to provide 30 relief for a persons suffering from sunburn by providing a moisturiser having a cooling effect to remove heat and/or pain away from the skin in the affected area, usually the N:Melboume\Cases\Patent\710O0-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 9 back, back of the neck, arms, legs and the like of the person suffering from sunburn. Typically, the moisturiser composition is a water based s moisturising system having a low oil phase content. More typically, the moisturiser is an emulsion based moisturiser composition. More typically, the emulsion is an oil in water emulsion or the like. However, other types of emulsions are possible including, water in oil, 10 water in oil in water, oil in water in oil or similar including any form of two or three phase emulsions. The emulsion can be a standard type emulsion, a nano emulsion, a micro-emulsion or the like. The emulsion can have a particle size of from about 0.0001 to 5000p, 15 preferably from about 0.5 to 10Op depending upon the type of emulsion. Typically, the propellant contains at least some dimethyl ether. The dimethyl ether can be used alone or other 20 propellants can be used in combination with the dimethyl ether in some formulations. Other propellants that could be used in the moisturising composition of the present invention include hydrocarbon propellants or hydrocarbon mixtures, such as for example, butane, isobutane, propane, 25 or mixtures of such materials. Ethers can be used as the propellant, particularly dimethyl ether, halo hydrocarbons including dimethyl ether or dichloro difluoro methane alone or in mixtures thereof including diflurotetraz, fluroethane or the like. Other propellants include 30 fluorinated hydrocarbons, vinyl chloride, nitrogen gas, carbon dioxide gas, nitrous oxides, or combination of two or more. N:\Melboume\Cases\Patent\71000-71999\P71901.AU-2\Specis\P71901.AU.2 Specification 2009-5-11 .doc 28105/09 - 10 Typically, the propellant is contained in the aerosol container or dispenser at pressures between about 5 and 2000 psig, preferably between about 4 and 200 psig, more preferably between about 20 and 100 psig, most preferably s between about 30 and 80 psig. Typically, the moisturiser composition is dispensed as droplets, preferably in the form of a fine mist, spray, aerosol, fog, or like combination of droplets or particles 10 of liquid in a gas, typically liquid in air and optionally including particles or droplets of the propellant, at least initially after delivery, as the propellant volatilisers on delivery of the moisturiser. Typically, the fine or very fine droplets of liquid moisturizer 15 composition are such that on contact with the skin, the droplets coalesce to form a layer or film of moisturiser on the skin, preferably a uniform layer or film having even coverage over the skin. Typically, the moisturiser optionally contains components that facilitate the 20 formation of a film, such as film forming materials. Typically, additional distribution of the composition is not required, such as using the hand or an applicator to further spread the composition over the skin since the 25 moisturiser is applied as a thin substantially uniform film over the entire surface of the affected area. Typically, the spray has a particle size or droplet size of from about 0.1p to about 5000p, preferably from about 0.2pL to about 1000p, more preferably from about 1.0[i to 30 about 500p. N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901 AU.2 Specification 2009-5-11.doc 28/05/09 - 11 Typically, the application of the moisturiser composition of the present invention has a cooling effect on the skin. Typically the cooling effect is immediate or almost immediate. More typically, the cooling effect lasts for a 5 short duration after application of the moisturiser composition. Typically, the moisturiser composition has a base composition. More typically, the base composition is an 10 emulsion. Typically, the base composition includes an oil phase and a water phase. More typically the oil and water phase form an emulsion. Even more typically, the moisturiser composition contains an emulsifier for assisting in promoting the formation of an emulsion from 15 the oil phase and the water phase, including multiple phases. Typically, there may be more than one oil phase or water phase. Typically, the moisturising effect is a physiological or 20 psychological effect to provide relief from the skin condition or is thought by the user of the moisturiser to provide relief from the skin condition. Typically, the moisturising composition contains other 25 components or additives. Forms of the additives include emollients, surfactants, soaps, cleansing agents, auxiliary moisturising agents, skin-feel agents, film forming agents, emulsifiers, silkiness enhancing agents, antioxidants, alcohols, solvents, preservatives, 30 fragrances, humectants, anti-ageing agents, anti-microbial agents, naturally derived extracts, vitamins, including vitamin E, or other materials to enhance moisturising properties. N \Melboume\Cases\Patent\71000-71999\P71901.AU 2\Specs\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 12 Moisturisers are included in the composition of the present invention to provide skin conditioning benefits and to provide the moisturising effect and aid in leaving 5 the skin feeling less taught, less dry, more moisturised, softer, smoother or the like. The aerosol composition of the present invention allows high levels of the moisturiser to be incorporated into the aerosol container without adversely effecting dispensing of the moisturiser 10 composition in the form of droplets, such as for example, in the form of a spray, mist or similar of fine and very fine liquid droplets thereby providing a better moisturising effect than available from conventional moisturiser composition in the form of lotions, gels or is creams which must be rubbed or otherwise spread or worked into the skin to provide any effect. It is to be noted that the size of the droplets can be altered depending upon circumstances in the range from 20 about 0.1 micron to about 5000 micron, preferably about 0.2 micron to about 1000 micron, more preferably from about 1.0 micron to about 500 micron. The moisturisers useful in the present invention are used 25 at a level of from about 1% to about 99% by weight of the total weight of the composition, preferably from about 10% to about 60%, more preferably from about 12% to about 40%, and most preferably from about 15% to about 40%, by weight. 30 Typical examples of moisturisers include glycerine, propyleneglycol, sorbitol, polyethylene glycol, and other materials having moisturising properties. N:\Melboume\Cases\Patent\7100-71999\P71901 .AU,2\Specis\P71901.AU.2 Specification 2009-5-11 doc 28/05/09 - 13 Although the term moisturiser is often used without exact definition, particularly within the cosmetic industry and/or skin conditioning industry, the meaning of the word 5 moisturiser as used in the present invention describes a material which imparts a smooth or soft feeling to the skin surface when applied to the skin. Another term for moisturiser is emollient. 10 Moisturising of skin can be derived in two ways. One way is to deposit a moisturiser on the surface of the skin as an occlusive layer which reduces the rate of evaporation of water from the skin. Another way is to add non occlusive hydroscopic materials to the skin that retain 15 water and/or adsorb water and make the retained water available to the skin to alter the physical properties of the skin and to produce a cosmetically desirable effect on the skin or to provide a smooth silky feel to the skin by the retention of the water content within the skin. 20 Emollients, is a term often used interchangeably with the word moisturisers. Emollients include water soluble polyols, glycerin, glycol, sorbitol, polyethylene glycol, ethoxylated ethers, propoxylated ethers, particularly of 25 methyl glucose, ethoxylated ethers of lanolin and propoxylated ethers of lanolin, mineral oil, lanolin oil, coconut oil, cocoa butter, olive oil, aloe extracts, jojoba oils, castor oil, fatty acids such as oleic and stearic, fatty alcohols such as cetyl and hexadecyl, 30 diisopropyl adipate, hydroxybenzoate esters, benzoic acid esters, particularly C10-C16 alcohols, isononyl iso nonanoate, alkanes such as mineral oil, silicones such as dimethyl polysiloxane, ethers such as polyoxypropylene N:\Mlboume\Cases\Patent\7100O71999\P71900 AU.2\SpecisU71901.AU 2 Specification 2009-5-11. doc 28/05/09 - 14 butyl ethers and polyoxypropylene cetyl ethers, and C12 C15 alkyl benzoates including mixtures of two or more of the above and other suitable materials. 5 Other additives include herbal extracts, such as for example, papaya skin rejuvenators, green tea counter irritation agents, other components having a physiological or psychological effect on the skin. 10 The occlusive type moisturisers include petrolatum, mineral oil, beeswax, silicon oil, lanolin and oil-soluble lanolin derivatives, saturated and unsaturated fatty alcohols such as benzyl alcohol, hydrocarbons such as squalene, and various animal and vegetable oils such as 15 almond oil, peanut oil, wheat germ oil, linseed oil, jojoba oil, oil of apricot pits, walnuts, palm nuts, pistachio nuts, sesame seeds, rapeseed, cade oil, corn oil, peach pit oil, poppy seed oil, pine oil, castor oil, soy bean oil, avocado oil, safflower oil, coconut oil, 20 hazelnut oil, olive oil, grape seed oil, sunflower seed oil, materials derived from plants including land plants, ocean plants, water plants, such as for example, seaweed, and extracts from marine animals, such as shark cartilage and other suitable materials. 25 Examples of other additives include polymeric skin feel aids such as for example, polymeric materials having a smooth or silky physiological or psychological effect on the skin. Examples of polymeric skin-feel aids useful in 30 the present invention are the cationic and non-ionic polymers used in the cosmetic field. It is preferred that cationic polymeric materials be used as they provide better skin feel benefits. Typical examples of emollients N :Melboume\Cases\Paten\71000-71999\P71901.AU 2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 15 include mineral oils, esters, natural oils, lanolin derivatives and the like. Examples of emollients include: glycerine, sorbitol, propylene glycol, isopropyl myristate, isopropyl palmitate, butylene glycol, caprys 5 caprylic triglyceride, coco-caprylate/caprate, cocoglycerides, or the like including combinations of two or more. More typically the emollients include mineral oil, lanolin 10 oil, coconut oil, cocoa butter, olive oil, aloe extracts, jojoba oils, castor oil, fatty acids such as oleic and stearic, fatty alcohols such as cetyl and hexadecyl, diisopropyl adipate, hydroxybenzoate esters, benzoic acid esters, particularly C10-C16 alcohols, isononyl iso 15 nonanoate, alkanes such as mineral oil, silicones such as dimethyl polysiloxane, ethers such as polyoxypropylene butyl ethers and polyoxypropylene cetyl ethers, and C12 C15 alkyl benzoates including mixtures of two or more of the above. 20 Emulsifiers can be used either alone or in combination with other emulsifiers or other ingredients. The amount of emulsifier added is from about 1% to about 30%, preferably from about 2% to about 20% by weight of the 25 weight of the total composition. Examples of emulsifiers include polyethyloxylated C8 to C22 fatty acids having less than about 30 moles of ethylene oxide per mol of fatty acid, ethoxylated esters, 30 un-ethoxylated esters, esters, polyoxyethylene fatty ether phosphates, fatty acid amides, phospholipids, polypropyoxylated fatty esters, acyl lactylates, polyethoxylated poly-oxypropylene-glycols, polypropyoxylated poly(oxyethylene)glycols, N:\Melboume\Cases\Paten\71000-71999\P71901 AU.2Specis\P71901.AU 2 Specification 2009-5-1i.doc 28/05/09 - 16 poly(oxyethylene)poly(oxypropylene)ethylene diamines and mixtures thereof. Examples of other emulsifiers include polyoxyethylene(8) 5 stearate, myristyl ethoxy(3) palmitate, methyl glucoside sesquistearate, sucrose stearate, sucrose laurate, sorbitan monolaureate, polyoxyethylene(3) oleyl ether phosphate, polyoxyethylene(1O) oleyl ether phosphate, lauric diethanolamide, stearic monoethanolamide, lecithin, 10 lanolin alcohol propoxylates, sodium stearoyl-2-lactylate, calcium stearoyl-2-lactylate and the like. Advantageously, the moisturiser further includes a humectant. Humectants are cosmetic ingredients intended 15 to increase the water content of the top layers of the skin. This group of ingredients includes primarily hygroscopic agents employed for this specific purpose. Humectants of particular interest for the present invention are polyols and alcohols such as sorbitol, 20 glycerol, ethylene glycol, propylene glycol or mixtures thereof. Preferably, the humectant contains a hydroxyl group. The humectant can act on the dermis of the skin, the epidermis of the skin or both dermis and epidermis. 25 Moisturisers used in the moisturising compositions according to the invention are those which aid retention of water to plasticise outer layers of the epidermis to promote soft, smooth skin. If water is lost more rapidly from the stratum corneum that it is received from the 30 lower layers of the epidermis, the skin becomes dehydrated and loses its flexibility. N :Melboume\Cases\Patent\71000-71999\P71901 AU 2\Specis\P71901 AU.2 Specification 2009-5-11.doc 28105/09 - 17 Moisturisers used in compositions according to the invention may typically work by one or a combination of three main routes, namely occlusion, humectancy and restoration of deficient materials. A given moisturising 5 composition may act by any number of these three preferred routes. Occlusion consists of reducing the rate of transepidermal water loss through old or damaged skin or in protecting 10 otherwise healthy skin from the effect of a drying environment. The second approach is to use humectants to attract water from the surrounding environment, thereby supplementing the skin's water content. The third approach is to determine the mechanism of the skin is moisturisation process, and supplement the skin in its deficiencies. The preferred cooling agent propellant for the compositions of the invention is dimethyl ether (DME), 20 which is available commercially as DYMELAO from E.I. Dupont de Nemours & Co. Dimethyl ether is fully compatible with the other components of the compositions of the invention, and may be formulated in amounts effective for achieving the desired degree of cooling. 25 Preferably, the compositions of the invention contain about 50% by weight of a moisturiser or moisturiser composition, and about 50% by weight propellant, of which 30 to 40% by weight of the composition is dimethyl ether. 30 Optionally, the amount of additional material of the propellant included as additional propellant is about 10 to 20% by weight of the composition and includes propellants such as isobutane, butane and propane. More N :Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 18 typically, the amount of propellant is 30% by weight based on the weight of the moisturiser, and the moisturiser is about 70% w/w of the combined weight of propellant and moisturiser composition, with the moisturiser having 2% 5 w/w of oil phase. The use of other propellants is possible, as well. Broadly, the compositions of the invention can contain from 10% up to 99.9% by weight propellant, with the propellant containing up to 75% by weight dimethyl ether. Greater amounts of dimethyl ether 10 used as propellant tend to produce excessive cooling, causing freezing, or at least a freezing sensation, on the surface of the skin. The preferred compositions of the invention are dispensed is from aerosol containers to form a mushroom-like shape at the application site, the compositions spreading easily and completely absorbing in the skin, disappearing quickly without leaving a heavy residue, partially because of the low oil content. The product has a good feel and achieves 20 a desirable cooling effect, quickly eliminating itching or other adverse conditions of the skin. A preferred stock solution for aerosol dispensing contains, by weight, 30% dimethyl ether, 10% isobutane 25 butane-propane mixture. The average droplet size of the moisturising phase droplets, which comprise the skin moisturising composition, ranges from about 0.005 microns to about 1000 30 microns, preferably from about 0.1 to about 500 microns, more preferably from about 10 to about 350 microns, and most preferably from about 50 to about 200 microns in diameter. N:AMelboume\Cases\Patent\71000-71999\P71901 AU 2\SpecisP71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 19 PRESERVATIVES Preservatives are optionally included in the moisturiser compositions of the present invention, if required 5 depending upon the exact formulation of the moisturiser composition. Preservatives are added to prevent spoilage of the moisturiser composition both before and after packaging. Preservatives are one example of additives added to the compositions. Additives, including io preservatives, antioxidants and similar materials can be incorporated into the moisturiser composition of the present invention. Typical examples of such preservatives or antioxidants include the parabens. Other examples include the following: vitamin E, vitamin E acetate, is vitamin C, butylated hydroxytoluene, methylparaben and mixtures thereof. One or more preservatives/antioxidants may be present in an amount of about 0.01 wt% to about 2 wt.% of the total weight of the moisturiser composition. Preferably, one or more preservatives/antioxidants are 20 present in an amount about 0.1 wt.% to about 1 wt.%. Typically, preservatives are added to the moisturiser formulation of the present invention in order to preserve the formulation against deterioration and/or degradation 25 including microbial growth or the like. Examples of preservatives include: BHA, BHT, phenoxyethanol, methyldibromo glutaro-nitrile, potassium sorbate, propylparaben, methylparraben, butylparraben, 30 ethylparraben, imidazolidinyl urea, and others including mixtures of two or more. Non limiting examples illustrating aspects of the present invention will now be described. 35 N:\Melboume\Cases\Patent\7100O-71999\P71901 AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 20 EXAMPLE 1 An aerosol moisturising composition is prepared as follows: 5 Into a suitable vessel are combined the components to form one embodiment of the moisturiser composition, such as for example, an emulsifying agent (Glyceryl Stearate), a solubilizing agent (Ceteareth - 20/30), one or more io emollients, and similar materials. The mixture is stirred and heated, such as for example, to 50 0 C or similar to provide a clear solution. In a separate vessel, water is heated. The moisturiser composition is then stirred into the water to form an emulsion. The emulsion is cooled and 15 other components added such as stabilizers for the emulsion, preservatives, anti-microbial agents or the like. The resulting product is mixed until uniform. The resulting emulsion is filled into a suitable aerosol 20 package of conventional type together with the dimethyl ether propellant in various proportions. The package is completed by attachment of a suitable dispensing valve and actuator to seal the package thereby forming a container of the finished product. 25 The product has the following formulation: 4.3% Glyceryl Stearate emulsifying agent 30 2.3% Ceteareth-20/ Ceteareth 30 surfactant 1.7% Dicaprylyl Carbonate emollient 2.9% Tocopherol Acetate anti-ageing agent 0.2% Cetaryl Alcohol emulsion stabiliser N:\Melboume\Cases\Patent\71000-71999\P71901.AU-2\Specis\P71901.AU.2 Specification 2009-5-11 doc 28/05/09 - 21 0.2% Phenyl Trimethicone anti-foaming agent 0.15% Glycerine humectant 38.0% Dimethyl ether propellant 50.2% Deionized water solubilizing agent 5 The resulting product can be tested for spray quality by a combination of inspection and by using standard test methods including test methods relating to pressure measurement and discharge rate of the aerosol container, io such as for example, measurements of spray rates, spray patterns and the like. It can also be tested for use characteristics by application to the skin of a number of individuals forming the test panel and evaluation of the product performance. 15 Other examples include the following: N:\Melboume\Cases\Patont\71000-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11 doc 28/05/09 - 22 EXAMPLE 2 An aerosol moisturiser composition is prepared according to the procedure of Example 1 and has the following 5 formulation. Typical formulations include the following: % w/w INCI NAME FUNCTION CHEMICAL CLASS 3.3 Glyceryl Stearate Emollient - emulsifying Glyceryl Esters agent 0.31 Ceteareth-20/ Surfactant - solubilising Polyethylene glycol ether; Ceteareth-30 agent alkoxylated alcohols 0.11 Dicaprylyl Carbonate Skin conditioning agent- Ester emollient 0.1 Hexyldecanol Skin conditioning agent- Hexyldecanol alcohol emollient 2.0 Cocoglycerides Skin conditioning agent- Glyceryl ester emollient 3.1 Tocopherol Acetate Anti-ageing agent Antioxidant 1.5 Cetearyl Alcohol Emulsion Stabilizer Fatty alcohol 5.0 Phenyl Trimethicone Anti-foaming agent Phenyl trimeticone siloxane and silane 62.18 Deionised Water Solubilizing agent Solvent 1.7 Glycerine/BP Skin conditioning agent- Polyol humectant 0.2 Panthenol Conditioning agent Alcohol and amide 1.5 Aloe Vera Soothing agent/ Antioxidant Natural Extract decolourised 2.5 Extrapone Green Tea Anti-ageing agent Antioxidant 3.7 Nipa Phenonip Anti-microbial Preservative 0.8 Fragrance Fragrance Fragrance 12.0 Dimethyl ether Propellant Ether N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901 AU.2 Specification 2009-5-11.doc 28/05/09 - 23 EXAMPLE 3 An aerosol moisturiser composition is prepared according to the procedure of Example 1 and has the following ranges 5 of various components in separate formulations. Typical formulations include the following: % w/w INCI NAME FUNCTION CHEMICAL CLASS 0.1 - 15 Glyceryl Stearate Emollient - emulsifying Glyceryl Esters agent 0.01 - 10 Ceteareth-20/ Surfactant - solubilising Polyethylene glycol ether; Ceteareth-30 agent alkoxylated alcohols 0.01 - 8 Dicaprylyl Carbonate Skin conditioning agent- Ester emollient 0.01 - 5 Hexyldecanol Skin conditioning agent- Hexyldecanol alcohol emollient 0.01 - 10 Cocoglycerides Skin conditioning agent- Glyceryl ester emollient 0.1 - 12 Tocopherol Acetate Anti-ageing agent Antioxidant 0.1 - 10 Cetearyl Alcohol Emulsion Stabilizer Fatty alcohol 1.0 - 20 Phenyl Trimethicone Anti-foaming agent Phenyl trimeticone siloxane and silane 10 - 85 Deionised Water Solubilizing agent Solvent 0.1 - 8 Glycerine/BP Skin conditioning agent- Polyol humectant 0.01 - 8 Panthenol Conditioning agent Alcohol and amide 0.1 - 10 Aloe Vera Soothing agent/ Antioxidant Natural Extract decolourised 0.1 - 15 Extrapone Green Tea Anti-ageing agent Antioxidant 0.1 - 18 Nipa Phenonip Anti-microbial Preservative 0.01 - 10 Fragrance Fragrance Fragrance 1.0 - 70 Dimethyl ether Propellant Ether N \Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU-2 Specification 2009-5-11 doc 28/05/09 - 24 EXAMPLE 4 An aerosol moisturiser composition is prepared according to the procedure of Example 1 and has the following ranges 5 of various components in separate formulations. Typical formulations include the following: % w/w INCI NAME FUNCTION CHEMICAL CLASS 1.0 - 8 Glyceryl Stearate Emollient - emulsifying Glyceryl Esters agent 0.01 - 5 Ceteareth-20/ Surfactant - solubilising Polyethylene glycol ether; Ceteareth-30 agent alkoxylated alcohols 0.01 - 4 Dicaprylyl Carbonate Skin conditioning agent- Ester emollient 0.01 - 5 Hexyldecanol Skin conditioning agent- Hexyldecanol alcohol emollient 0.01 - 7 Cocoglycerides Skin conditioning agent- Glyceryl ester emollient 1.0 - 7 Tocopherol Acetate Anti-ageing agent Antioxidant 0.1 - 6 Cetearyl Alcohol Emulsion Stabilizer Fatty alcohol 2.0 - 8 Phenyl Trimethicone Anti-foaming agent Phenyl trimeticone siloxane and silane 30 - 70 Deionised Water Solubilizing agent Solvent 0.1 - 5 Glycerine/BP Skin conditioning agent- Polyol humectant 0.01 - 3 Panthenol Conditioning agent Alcohol and amide 0.1 - 8 Aloe Vera Soothing agent/ Antioxidant Natural Extract decolourised 0.1 - 10 Extrapone Green Tea Anti-ageing agent Antioxidant 0.1 - 12 Nipa Phenonip Anti-microbial Preservative 0.01 - 6 Fragrance Fragrance Fragrance 3.0 - 50 Dimethyl ether Propellant Ether N \Melboume\Cases\Patent\71000-71999\P71901 AU.2\Specrs\P71901 AU 2 Specification 2009-5-11.doc 28/05/09 - 25 It will be understood to persons skilled in the art of the invention that many modifications may be made without departing from the spirit and scope of the invention. 5 In the claims which follow and in the preceding description of the invention, except where the context requires otherwise due to express language or necessary implication, the word "comprise" or variations such as "comprises" or "comprising" is used in an inclusive sense, 10 i.e. to specify the presence of the stated features but not to preclude the presence or addition of further features in various embodiments of the invention. N :Melboume\Cases\Patent71000-71999\P71901.AU.2\Specis\P71901 AU.2 Specification 2009-5-11 doc 28/05/09

Claims (24)

1. A moisturiser composition capable of being dispensed s from a pressurised container in the form of droplets of the moisturiser composition for direct application to the skin of a person suffering from a skin condition to provide a substantially uniform coverage of the moisturiser over the skin without the need to 10 additionally distribute the moisturiser over the skin.

2. An aerosol dispenser containing a moisturiser composition or a moisturiser containing composition 15 in which the moisturiser composition can be dispensed from the dispenser in the form of droplets of the moisturiser composition for direct application to the skin of a person suffering from a skin condition requiring alleviation by contact with the moisturiser 20 composition to provide a uniform coverage of the moisturiser composition over the skin to provide a moisturising effect to the skin wherein after the moisturiser composition is applied, there is no need to additionally distribute the moisturiser 25 composition in contact with the skin to effect the substantially uniform coverage.

3. A moisturiser composition capable of being dispensed from an aerosol container, the moisturiser 30 composition comprising from about 1 to about 99% by weight of an emulsion composition and from about 99% to about 1% by weight of a propellant composition in which the emulsion composition includes at least one N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 27 moisturiser or moisturising agent and the propellant is at least in part dimethyl ether, said moisturizer composition being dispensed from the aerosol container in the form of droplets to provide a 5 substantially uniform coverage of the moisturiser composition over the skin to which the composition is applied thereby providing at least a moisturising effect to the skin without the need to additionally distribute the moisturiser composition over the skin 10 after the moisturiser is applied to the skin to provide uniform coverage.

4. A moisturiser composition or method according to any preceding claim in which the moisturiser is a low oil 15 phase composition or has a low oil content.

5. A moisturiser composition or method according to any preceding claim in which the amount of oil in the moisturiser composition is less than about 10% by 20 weight, preferably less than about 5% by weight, more preferably less than about 3% by weight or most preferably from about 1 to 2% by weight.

6. A moisturiser composition or method according to any 25 preceding claim in which the moisturiser composition is capable of contactless application to the skin or body of a person to which the moisturiser is applied.

7. A moisturiser composition or method according to any 30 preceding claim in which the moisturiser provides a therapeutic, pharmaceutical, dermatological, physiological, psychological or other effect or N :\elbume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 28 benefit on the skin of the person to which the moisturiser composition is applied.

8. A moisturiser composition or method according to any s preceding claim in which the moisturiser composition provides relief from the effect of sunburn including both relief from the pain of sunburn and the build up of heat caused by sunburn in the body. 10 9. A moisturiser composition or method according to any preceding claim in which the moisturiser composition is a water based moisturising composition having a low oil base content. 15 10. A moisturiser composition or method according to any preceding claim in which the moisturiser composition further includes an emulsion based moisturizer composition in which the emulsion is an oil in water emulsion. 20

11. A moisturiser composition or method according to any preceding claim in which the emulsion moisturiser composition is substantially alcohol free, or substantially free of a material that produces a free 25 alcohol so as not to irritate the skin or aggravate the skin condition for which the moisturiser composition is applied to the skin.

12. A moisturiser composition or method according to any 30 preceding claim further comprising a propellant wherein the propellant includes at least some dimethyl ether. N:\Melboume\Cases\Paten\71000-71999\P71901 AU 2\Specis\P71901.AU.2 Specification 2009-5-11 doc 28105/09 - 29 13. A moisturiser composition or method according to any preceding claim in which the propellant includes hydrocarbon propellants or hydrocarbon propellant mixtures including butane, isobutane, propane, or 5 mixtures of such materials.

14. A moisturiser composition or method according to any preceding claim in which the composition comprises about 50% moisturiser or moisturiser composition and 10 about 50% by weight propellant of which about 30% to about 40% by weight of the composition is dimethyl ether and about 10% to about 20% by weight of the composition is isobutane, butane, propane or mixtures thereof. 15

15. A moisturiser composition or method according to any preceding claim in which the moisturiser composition further includes ether as the propellant including dimethyl ether, halo hydrocarbons, dichloro difluoro 20 methane or mixtures including diflurotetraz, fluroethane or similar, fluorinated hydrocarbons and the like.

16. A moisturiser composition or method according to any 25 preceding claim in which the moisturiser composition is dispensed from the dispenser in the form of droplets of a fine mist, spray, aerosol, or like combination of droplets or particles of liquid in a gas, typically liquid in air. 30

17. A moisturiser composition or method according to any preceding claim in which the fine or very fine droplets of liquid moisturiser composition are such a N \MelboumA\Cases\Putent\71000-71999\P71901AU.2\Specis\P71901 AU 2 Specification 2009-5-11.doc 26/05/09 - 30 size that the droplets on contact with the skin coalesce to form a layer or film of moisturiser on the skin, preferably a uniform layer having substantially even coverage over the skin, 5 particularly over the affected area of the skin.

18. A moisturiser composition or method according to any preceding claim further comprising other components or additives wherein the other components or 10 additives include emollients, surfactants, soaps, cleansing agents, auxiliary moisturising agents, skin-feel agents, emulsifiers, silkiness enhancing agents, antioxidant, alcohols, solvents, preservatives, fragrances, humectants, anti-ageing 15 agents, anti-microbial agents and the like.

19. A moisturiser composition or method according to any preceding claim in which the amount of moisturiser in the composition is from about 1% to 99% by weight, 20 preferably from about 10% to 60% by weight, or preferably from about 12% to 40% by weight, and most preferably from about 15% to 40% by weight.

20. A moisturiser composition or method according to any 25 preceding claim in which the moisturiser includes glycerine, propyleneglycol, sorbitol, polyethylene glycol and similar ethoxylated ethers, propoxylated ethers, methyl glucose, ethoxylated ethers of lanolin and propoxylated ethers of lanolin. 30

21. A moisturiser composition or method according to any preceding claim further comprising papaya skin rejuvenators, green tea counter irritation agents, N:Melboume\Cases\Patent\71000-71999\P71901 AU 2MSpecis\P71901.AU 2 Specification 2009-S-II.doc 28/05/09 - 31 other components having a physiological or psychological effect on the skin, petrolatum, mineral oil, beeswax, silicon oil, lanolin and oil-soluble lanolin derivatives, saturated and unsaturated fatty 5 alcohols such as benzyl alcohol, hydrocarbons such as squalene, and various animal and vegetable oils such as almond oil, peanut oil, wheat germ oil, linseed oil, jojoba oil, oil of apricot pits, walnuts, palm nuts, pistachio nuts, sesame seeds, rapeseed, cade 10 oil, corn oil, peach pit oil, poppy seed oil, pine oil, castor oil, soy bean oil, avocado oil, safflower oil, coconut oil, hazelnut oil, olive oil, grape see oil and sunflower seed oil. 15 22. A moisturiser composition or method according to any preceding claim in which the composition contains an emulsifier either alone or in combination with other emulsifiers wherein the amount of emulsifier or emulsifiers is from about 1% to about 30% by weight 20 of the total weight of composition, preferably from about 2% to about 20% by weight of the weight of the total composition.

23. A moisturiser composition or method according to any 25 preceding claim in which the emulsifier includes polyethyloxylated C8 to C22 fatty acids having less than about 30 moles of ethylene oxide per mol of fatty acid, ethoxylated esters, un-ethoxylated esters, sugar esters, polyoxyethylene fatty ether 30 phosphates, fatty acid amides, phospholipids, polypropyoxylated fatty esters, acyl lactylates, polyethoxylated poly-oxypropylene-glycols, polypropyoxylated poly(oxyethylene)glycols, N:\Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specs\P71901.AU 2 Specification 2009-5-11.doc 28/05/09 - 32 poly(oxyethylene)poly(oxypropylene)ethylene diamines and mixtures thereof, polyoxyethylene(8) stearate, myristyl ethoxy(3) palmitate, methyl glucoside sesquistearate, sucrosedi stearate, sucrose laurate, 5 sorbitan monolaureate, polyoxyethylene(3) oleyl ether phosphate, polyoxyethylene(10) oleyl ether phosphate, lauric diethanolamide, stearic monoethanolamide, lecithin, lanolin alcohol propoxylates, sodium stearoyl-2-lactylate, calcium stearoyl-2-lactylate 10 and the like.

24. A moisturiser composition or method according to any preceding claim in which the propellant includes 30% dimethyl ether and 10% isobutane butane propane 15 mixture.

25. A moisturiser composition or method according to any preceding claim in which the average droplet size of the moisturising droplets ranges from about 0.005 20 microns to about 1000 microns, preferably from about 0.1 to about 500 microns, more preferably from about 10 to about 350 microns, and most preferably from about 50 to about 200 microns in diameter. 25 26. A moisturiser composition having the following formulation: 4.3% Glyceryl Stearate 2.3% Ceteareth-20/ Ceteareth 30 30 1.7% Dicaprylyl Carbonate 2.9% Tocopherol Acetate 0.2% Cetaryl Alcohol 0.2% Phenyl Trimethicone N:\Melboume\Cases\Patent\71000-71999\P71901 AU 21Specis\P71901.AU.2 Specification 2009-5-11.doc 28/05/09 - 33 0.15% Glycerine

38.0% Dimethyl ether

50.2% Deionized water 5 27. A moisturiser composition having the following formula: % w/w INCI NAME 10 3.3 Glyceryl Stearate 0.31 Ceteareth-20/ Ceteareth-30 0.11 Dicaprylyl Carbonate 0.1 Hexyldecanol 2.0 Cocoglycerides 3.1 Tocopherol Acetate 15 1.5 Cetearyl Alcohol 5.0 Phenyl Trimethicone

62.18 Delonised Water 1.7 Glycerine/BP 0.2 Panthenol 20 1.5 Aloe Vera decolourised 2.5 Extrapone Green Tea 3.7 Nipa Phenonip 0.8 Fragrance 12.0 Dimethyl ether N:\Melboume\Cases\Patent\71000-71999\P71901 .AU.2\Specis\P71901.AU.2 Specification 2009-5-11 .doc 28/05109 - 34 28. A moisturiser composition having the following formula: 5 % w/w INCI NAME 0.1 - 15 Glyceryl Stearate 0.01 - 10 Ceteareth-20/ Ceteareth-30 10 0.01 - 8 Dicaprylyl Carbonate 0.01 - 5 Hexyldecanol 0.01 - 10 Cocoglycerides 0.1 - 12 Tocopherol Acetate 0.1 - 10 Cetearyl Alcohol 15 1.0 - 20 Phenyl Trimethicone 10 - 85 Deionised Water 0.1 - 8 Glycerine/BP 0.01 - 8 Panthenol 0.1 - 10 Aloe Vera decolourised 0.1 - 15 Extrapone Green Tea 20 0.1 - 18 Nipa Phenonip 0.01 - 10 Fragrance 1.0 - 70 Dimethyl ether N :Melboume\Cases\Patent\71000-71999\P71901.AU.2\Spocis\P71901 AU.2 Specification 2009-5-11.doc 28/05/09 - 35 29. A moisturiser composition having the following formula: 5 % w/w INCI NAME 1.0 - 8 Glyceryl Stearate 0.01 - 5 Ceteareth-20/ Ceteareth-30 0.01 - 4 Dicaprylyl Carbonate 10 0.01 - 5 Hexyldecanol 0.01 - 7 Cocoglycerides 1.0 - 7 Tocopherol Acetate 0.1 - 6 Cetearyl Alcohol 2.0 - 8 Phenyl Trimethicone 15 30 - 70 Delonised Water 0.1 - 5 Glycerine/BP 0.01 - 3 Panthenol 0.1 - 8 Aloe Vera decolourised 0.1 - 10 Extrapone Green Tea 20 0.1 - 12 Nipa Phenonip 0.01 - 6 Fragrance 3.0 - 50 Dimethyl ether 30. A moisturising composition substantially as 25 hereinbefore described with reference to the accompanying examples. 31. An aerosol dispenser containing a moisturiser composition or a moisturiser containing composition 30 substantially as hereinbefore described with reference to the accompanying examples. N \Melboume\Cases\Patent\71000-71999\P71901.AU.2\Specis\P71901.AU 2 Specification 2009-5-11 doc 28/05/09 - 36 32. A moisturiser composition capable of being dispensed from an aerosol container substantially as hereinbefore described with reference to the 5 accompanying examples. 33. Every novel feature as hereinbefore disclosed or defined in the specification and/or drawings when taken alone or in combination with any other feature 10 including features that are novel or otherwise, including groups of two or more features. N:\Melboume\Cases)Patent\71000-71999\P71901 AU.2\Specs\P71901.AU.2 Specification 2009-5-11 doc 28/05/09