AU2008325237B2 - Optical sensor for determining the concentration of an analyte - Google Patents
Optical sensor for determining the concentration of an analyte Download PDFInfo
- Publication number
- AU2008325237B2 AU2008325237B2 AU2008325237A AU2008325237A AU2008325237B2 AU 2008325237 B2 AU2008325237 B2 AU 2008325237B2 AU 2008325237 A AU2008325237 A AU 2008325237A AU 2008325237 A AU2008325237 A AU 2008325237A AU 2008325237 B2 AU2008325237 B2 AU 2008325237B2
- Authority
- AU
- Australia
- Prior art keywords
- radiation
- analyte
- detector
- concentration
- radiation beam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 96
- 239000012491 analyte Substances 0.000 title claims description 56
- 238000000034 method Methods 0.000 claims abstract description 67
- 239000000523 sample Substances 0.000 claims abstract description 60
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 48
- 239000008103 glucose Substances 0.000 claims abstract description 48
- 230000000737 periodic effect Effects 0.000 claims abstract description 24
- 230000005855 radiation Effects 0.000 claims description 251
- 238000012360 testing method Methods 0.000 claims description 47
- 238000010521 absorption reaction Methods 0.000 claims description 23
- 230000001678 irradiating effect Effects 0.000 claims description 23
- 230000008569 process Effects 0.000 claims description 23
- 239000000835 fiber Substances 0.000 claims description 20
- 230000001052 transient effect Effects 0.000 claims description 18
- 239000013307 optical fiber Substances 0.000 claims description 15
- 230000010355 oscillation Effects 0.000 claims description 12
- 239000012530 fluid Substances 0.000 claims description 6
- 230000001419 dependent effect Effects 0.000 claims description 3
- 230000004044 response Effects 0.000 claims description 3
- 229910052779 Neodymium Inorganic materials 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 claims description 2
- 239000000126 substance Substances 0.000 abstract description 15
- 238000001514 detection method Methods 0.000 abstract description 4
- 230000005284 excitation Effects 0.000 abstract description 4
- 210000001519 tissue Anatomy 0.000 description 29
- 239000000306 component Substances 0.000 description 26
- 239000008280 blood Substances 0.000 description 12
- 210000004369 blood Anatomy 0.000 description 12
- 238000004458 analytical method Methods 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 238000005259 measurement Methods 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 206010012601 diabetes mellitus Diseases 0.000 description 5
- 230000008901 benefit Effects 0.000 description 3
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- 238000004364 calculation method Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000010191 image analysis Methods 0.000 description 3
- 238000004867 photoacoustic spectroscopy Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 238000009534 blood test Methods 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 210000003722 extracellular fluid Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229910052691 Erbium Inorganic materials 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
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- 238000003491 array Methods 0.000 description 1
- 238000010420 art technique Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
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- 235000005911 diet Nutrition 0.000 description 1
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- 238000003487 electrochemical reaction Methods 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
- G01N2021/1725—Modulation of properties by light, e.g. photoreflectance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US196007P | 2007-11-05 | 2007-11-05 | |
| US61/001,960 | 2007-11-05 | ||
| PCT/US2008/012349 WO2009061367A2 (en) | 2007-11-05 | 2008-10-31 | Optical sensor for determining the concentration of an analyte |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008325237A1 AU2008325237A1 (en) | 2009-05-14 |
| AU2008325237B2 true AU2008325237B2 (en) | 2014-05-01 |
Family
ID=40292516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008325237A Ceased AU2008325237B2 (en) | 2007-11-05 | 2008-10-31 | Optical sensor for determining the concentration of an analyte |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9915608B2 (enExample) |
| EP (1) | EP2207474B1 (enExample) |
| JP (1) | JP5646337B2 (enExample) |
| CN (2) | CN101917899B (enExample) |
| AU (1) | AU2008325237B2 (enExample) |
| CA (1) | CA2704789C (enExample) |
| IL (1) | IL205499A (enExample) |
| TW (1) | TWI468688B (enExample) |
| WO (1) | WO2009061367A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10876965B2 (en) | 2015-12-09 | 2020-12-29 | Diamontech Ag | Apparatus and method for analyzing a material |
| US11280728B2 (en) | 2015-12-09 | 2022-03-22 | Diamontech Ag | Device and method for analyzing a material |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10413188B2 (en) * | 2004-11-17 | 2019-09-17 | Lawrence Livermore National Security, Llc | Assessment of tissue or lesion depth using temporally resolved light scattering spectroscopy |
| US20090156932A1 (en) | 2007-12-13 | 2009-06-18 | Board Of Trustees Of The University Of Arkansas | Device and method for in vivo flow cytometry using the detection of photoacoustic waves |
| US9451884B2 (en) | 2007-12-13 | 2016-09-27 | Board Of Trustees Of The University Of Arkansas | Device and method for in vivo detection of clots within circulatory vessels |
| EP2525194A1 (en) * | 2011-05-16 | 2012-11-21 | Knowles Electronics Asia PTE. Ltd. | Optical sensor |
| EP2805676A4 (en) * | 2012-01-18 | 2015-09-02 | Canon Kk | DEVICE FOR COLLECTING PERSONNEL INFORMATION AND METHOD FOR DETECTING PERSONNEL INFORMATION |
| CA2884954A1 (en) | 2012-09-25 | 2014-04-03 | Mark S. Smeltzer | Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood |
| CA2904031A1 (en) * | 2013-03-14 | 2014-10-02 | Profusa, Inc. | Method and device for correcting optical signals |
| EP3003131B1 (en) * | 2013-06-06 | 2020-05-27 | Profusa, Inc. | Apparatus for detecting optical signals from implanted sensors |
| US20150051473A1 (en) * | 2013-08-15 | 2015-02-19 | Covidien Lp | Systems and methods for photoacoustic spectroscopy |
| KR102270798B1 (ko) | 2013-12-16 | 2021-06-30 | 삼성메디슨 주식회사 | 광음향 프로브 및 광음향 진단 장치 |
| KR102143632B1 (ko) * | 2013-12-30 | 2020-08-11 | 삼성메디슨 주식회사 | 광음향 프로브 및 광음향 진단장치 |
| CN104000599B (zh) * | 2014-05-07 | 2016-06-01 | 辛勤 | 一种测量血糖浓度的方法及便携式设备 |
| DE102014108424B3 (de) * | 2014-06-16 | 2015-06-11 | Johann Wolfgang Goethe-Universität | Nicht-invasive Stoffanalyse |
| KR102244992B1 (ko) | 2014-10-17 | 2021-04-28 | 삼성전자주식회사 | 부하 전류 정보를 제공하는 전력관리 집적회로 및 그것을 포함하는 전자 장치 |
| KR102390874B1 (ko) | 2014-10-29 | 2022-04-26 | 삼성전자주식회사 | 혈당 측정기 및 그에 따른 혈당 측정 방법 |
| CN104490403B (zh) * | 2014-12-06 | 2016-08-17 | 深圳市贝沃德克生物技术研究院有限公司 | 基于光谱技术的无创血糖测量系统及其测量方法 |
| CA2970536C (en) | 2014-12-31 | 2023-09-26 | Vladimir Pavlovich Zharov | Devices and methods for fractionated photoacoustic flow cytometry |
| CN104586370B (zh) * | 2014-12-31 | 2018-01-30 | 歌尔股份有限公司 | 一种光电式脉搏信号测量方法、装置及测量设备 |
| US9949695B2 (en) | 2014-12-31 | 2018-04-24 | Goertek Inc. | Photoelectric type pulse signal measuring method and apparatus |
| US10267956B2 (en) | 2015-04-14 | 2019-04-23 | California Institute Of Technology | Multi-wavelength optical dielectric metasurfaces |
| FR3035716B1 (fr) * | 2015-04-30 | 2019-06-21 | Biomerieux | Machine et procede pour la detection automatisee in vitro d'analytes mettant en oeuvre une decomposition spectrale chromatique d'une reponse optique |
| US9696259B2 (en) * | 2015-08-18 | 2017-07-04 | Lumasense Technologies Holdings, Inc. | Optode sensor with integrated reference |
| US10881336B2 (en) | 2015-08-21 | 2021-01-05 | California Institute Of Technology | Planar diffractive device with matching diffraction spectrum |
| US10670782B2 (en) | 2016-01-22 | 2020-06-02 | California Institute Of Technology | Dispersionless and dispersion-controlled optical dielectric metasurfaces |
| KR101746352B1 (ko) | 2016-04-29 | 2017-06-12 | 다담마이크로 주식회사 | 광반사 측정법을 이용한 비침습식 혈당 측정 방법 및 장치 |
| EP3315069A1 (en) | 2016-10-25 | 2018-05-02 | Roche Diabetes Care GmbH | Method for determination of an analyte concentration in a body fluid and analyte concentration measurement device |
| GB2557311B (en) * | 2016-12-06 | 2021-05-12 | Rsp Systems As | Analyte Detection apparatus and method of detecting an analyte |
| US10666321B2 (en) * | 2016-12-29 | 2020-05-26 | Tektronix, Inc. | Sampling gate for broadband frequency reconstruction |
| US10488651B2 (en) | 2017-04-10 | 2019-11-26 | California Institute Of Technology | Tunable elastic dielectric metasurface lenses |
| CA3061993C (en) | 2017-05-22 | 2025-04-01 | Univ Gent | III-V/IV LASER SENSOR SYSTEM-CHIP FOR REAL-TIME MONITORING OF BLOOD COMPONENT CONCENTRATION LEVELS |
| CN107997769A (zh) * | 2017-11-24 | 2018-05-08 | 天津大学 | 一种基于耳垂血液层的微波时延无创血糖浓度检测法 |
| JP6845182B2 (ja) * | 2018-05-01 | 2021-03-17 | 日本電信電話株式会社 | 成分濃度測定装置 |
| AU2020331683B2 (en) * | 2019-08-16 | 2025-08-14 | Glucomat Gmbh | Active miniaturized sensing system and method |
| CN115177244A (zh) * | 2022-03-03 | 2022-10-14 | 北京理工大学 | 基于差分拉曼光谱的微型无创血糖检测系统 |
| CN115227286B (zh) * | 2022-06-28 | 2025-01-03 | 同济大学 | 超声探头自适应引导穿刺的装置、方法及采血箱 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5657754A (en) * | 1995-07-10 | 1997-08-19 | Rosencwaig; Allan | Apparatus for non-invasive analyses of biological compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4573761A (en) * | 1983-09-14 | 1986-03-04 | The Dow Chemical Company | Fiber-optic probe for sensitive Raman analysis |
| US5119815A (en) * | 1988-12-21 | 1992-06-09 | Nim, Incorporated | Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation |
| JP4212007B2 (ja) | 1996-11-26 | 2009-01-21 | パナソニック電工株式会社 | 血液成分濃度の分析装置 |
| JP4120684B2 (ja) * | 1996-11-26 | 2008-07-16 | 松下電工株式会社 | 分光分析法による血液成分濃度の分析装置 |
| US5941821A (en) * | 1997-11-25 | 1999-08-24 | Trw Inc. | Method and apparatus for noninvasive measurement of blood glucose by photoacoustics |
| US6097975A (en) * | 1998-05-13 | 2000-08-01 | Biosensor, Inc. | Apparatus and method for noninvasive glucose measurement |
| AU2001259435A1 (en) * | 2000-05-03 | 2001-11-12 | Stephen T Flock | Optical imaging of subsurface anatomical structures and biomolecules |
| US6635491B1 (en) * | 2000-07-28 | 2003-10-21 | Abbott Labortories | Method for non-invasively determining the concentration of an analyte by compensating for the effect of tissue hydration |
| EP1311189A4 (en) * | 2000-08-21 | 2005-03-09 | Euro Celtique Sa | Near-BLOOD GLUCOSE MONITORING DEVICE |
| CA2476421A1 (en) * | 2002-03-08 | 2003-09-18 | Sensys Medical, Inc. | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
| JP3590047B1 (ja) | 2003-09-24 | 2004-11-17 | 株式会社日立製作所 | 光学測定装置及びそれを用いた血糖値測定装置 |
| US20050277872A1 (en) * | 2004-05-24 | 2005-12-15 | Colby John E Jr | Apparatus and method for mobile medical services |
| JP2009509140A (ja) * | 2005-09-15 | 2009-03-05 | パロマー・メデイカル・テクノロジーズ・インコーポレーテツド | 皮膚の光学的判定デバイス |
-
2008
- 2008-10-31 CN CN200880124606.9A patent/CN101917899B/zh not_active Expired - Fee Related
- 2008-10-31 US US12/741,350 patent/US9915608B2/en not_active Expired - Fee Related
- 2008-10-31 EP EP08846768.3A patent/EP2207474B1/en not_active Not-in-force
- 2008-10-31 JP JP2010533075A patent/JP5646337B2/ja not_active Expired - Fee Related
- 2008-10-31 CN CN201110391618.1A patent/CN102512175B/zh not_active Expired - Fee Related
- 2008-10-31 WO PCT/US2008/012349 patent/WO2009061367A2/en not_active Ceased
- 2008-10-31 AU AU2008325237A patent/AU2008325237B2/en not_active Ceased
- 2008-10-31 CA CA2704789A patent/CA2704789C/en not_active Expired - Fee Related
- 2008-11-04 TW TW97142521A patent/TWI468688B/zh not_active IP Right Cessation
-
2010
- 2010-05-02 IL IL205499A patent/IL205499A/en not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5657754A (en) * | 1995-07-10 | 1997-08-19 | Rosencwaig; Allan | Apparatus for non-invasive analyses of biological compounds |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10876965B2 (en) | 2015-12-09 | 2020-12-29 | Diamontech Ag | Apparatus and method for analyzing a material |
| US11280728B2 (en) | 2015-12-09 | 2022-03-22 | Diamontech Ag | Device and method for analyzing a material |
| US12066378B2 (en) | 2015-12-09 | 2024-08-20 | DiaMon Tech AG | Device and method for analyzing a material |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102512175A (zh) | 2012-06-27 |
| CN101917899B (zh) | 2014-03-12 |
| AU2008325237A1 (en) | 2009-05-14 |
| JP5646337B2 (ja) | 2014-12-24 |
| WO2009061367A2 (en) | 2009-05-14 |
| CA2704789A1 (en) | 2009-05-14 |
| US9915608B2 (en) | 2018-03-13 |
| EP2207474A2 (en) | 2010-07-21 |
| HK1172229A1 (zh) | 2013-04-19 |
| CN102512175B (zh) | 2015-12-02 |
| CA2704789C (en) | 2018-07-24 |
| EP2207474B1 (en) | 2018-08-22 |
| TW200935054A (en) | 2009-08-16 |
| JP2011502627A (ja) | 2011-01-27 |
| HK1151958A1 (en) | 2012-02-17 |
| TWI468688B (zh) | 2015-01-11 |
| CN101917899A (zh) | 2010-12-15 |
| US20110105867A1 (en) | 2011-05-05 |
| WO2009061367A3 (en) | 2009-08-13 |
| IL205499A0 (en) | 2010-12-30 |
| IL205499A (en) | 2013-03-24 |
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