AU2008319366B2 - Benzomorpholine derivatives and methods of use - Google Patents

Benzomorpholine derivatives and methods of use Download PDF

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Publication number
AU2008319366B2
AU2008319366B2 AU2008319366A AU2008319366A AU2008319366B2 AU 2008319366 B2 AU2008319366 B2 AU 2008319366B2 AU 2008319366 A AU2008319366 A AU 2008319366A AU 2008319366 A AU2008319366 A AU 2008319366A AU 2008319366 B2 AU2008319366 B2 AU 2008319366B2
Authority
AU
Australia
Prior art keywords
compound
usa
compounds
agents
vegf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008319366A
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English (en)
Other versions
AU2008319366A1 (en
Inventor
Mina Dilmeghani Seran
Jean-Christophe Harmange
Jay Larrow
Matthew W. Martin
Joseph F. Payack
Raju Subramanian
Yohannes Teffera
Ryan White
Roger Zanon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AU2008319366A1 publication Critical patent/AU2008319366A1/en
Application granted granted Critical
Publication of AU2008319366B2 publication Critical patent/AU2008319366B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2008319366A 2007-10-29 2008-10-28 Benzomorpholine derivatives and methods of use Ceased AU2008319366B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94807P 2007-10-29 2007-10-29
US61/000,948 2007-10-29
PCT/US2008/012224 WO2009058267A2 (en) 2007-10-29 2008-10-28 Benzomorpholine derivatives and methods of use

Publications (2)

Publication Number Publication Date
AU2008319366A1 AU2008319366A1 (en) 2009-05-07
AU2008319366B2 true AU2008319366B2 (en) 2012-03-01

Family

ID=40394086

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008319366A Ceased AU2008319366B2 (en) 2007-10-29 2008-10-28 Benzomorpholine derivatives and methods of use

Country Status (8)

Country Link
US (1) US7795254B2 (cg-RX-API-DMAC7.html)
EP (1) EP2220078B1 (cg-RX-API-DMAC7.html)
JP (1) JP5343082B2 (cg-RX-API-DMAC7.html)
AU (1) AU2008319366B2 (cg-RX-API-DMAC7.html)
CA (1) CA2703257C (cg-RX-API-DMAC7.html)
ES (1) ES2417009T3 (cg-RX-API-DMAC7.html)
MX (1) MX2010004620A (cg-RX-API-DMAC7.html)
WO (1) WO2009058267A2 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH684182A5 (de) 1991-10-15 1994-07-29 Escher Wyss Ag Rotationsdruckmaschine.
RU2580318C2 (ru) 2010-05-19 2016-04-10 Сандоз Аг Получение промежуточных продуктов для синтеза позаконазола
US9206146B2 (en) 2010-05-19 2015-12-08 Sandoz Ag Purification of posaconazole and of posaconazole intermediates
US9199919B2 (en) 2010-05-19 2015-12-01 Sandoz Ag Process for the preparation of chiral hydrazides
CN108329303A (zh) 2011-06-16 2018-07-27 桑多斯股份公司 制备手性化合物的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070891A2 (en) * 2004-01-23 2005-08-04 Amgen Inc Compounds and methods of use

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US3755332A (en) * 1971-07-01 1973-08-28 Ciba Geigy Corp Substituted 4 indazolaminoquinolines
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB9323290D0 (en) * 1992-12-10 1994-01-05 Zeneca Ltd Quinazoline derivatives
AU4547396A (en) 1995-01-31 1996-08-21 Zenyaku Kogyo Kabushiki Kaisha Thioquinoline derivatives
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
GB9505702D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd Fungicidal compounds
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
AU7340096A (en) * 1995-11-07 1997-05-29 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
JPH10512896A (ja) * 1995-11-14 1998-12-08 フアルマシア・エ・アツプジヨン・エツセ・ピー・アー アリールおよびヘテロアリールプリン化合物
GB9603095D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
DE19614718A1 (de) * 1996-04-15 1997-10-16 Hoechst Schering Agrevo Gmbh Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung, und ihre Verwendung als Schädlingsbekämpfungsmittel
GB9800575D0 (en) 1998-01-12 1998-03-11 Glaxo Group Ltd Heterocyclic compounds
US6573289B1 (en) * 1998-04-23 2003-06-03 Takeda Chemical Industries, Ltd. Naphthalene derivatives, their production and use
HUP0103386A3 (en) * 1998-08-21 2002-07-29 Parker Hughes Inst St Paul Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
IL144745A0 (en) * 1999-02-10 2002-06-30 Astrazeneca Ab Quinazoline derivatives as angiogenesis inhibitors
US6258820B1 (en) * 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
EP1183254B1 (en) * 1999-04-12 2005-01-12 Aventis Pharma Limited Substituted bicyclic heteroaryl compounds as integrin antagonists
JP2004511479A (ja) * 2000-10-13 2004-04-15 アストラゼネカ　アクチボラグ キナゾリン誘導体
KR100600550B1 (ko) * 2000-10-20 2006-07-13 에자이 가부시키가이샤 질소 함유 방향환 유도체
DE60233736D1 (de) * 2001-06-22 2009-10-29 Kirin Pharma K K Chinolinderivat und chinazolinderivat, die die selbstphosphorylierung des hepatocytus-proliferator-rezeptors hemmen, und diese enthaltende medizinische zusammensetzung
DE60231230D1 (de) * 2001-11-03 2009-04-02 Astrazeneca Ab Quinazolin derivate als antitumor-mittel
GB0126433D0 (en) * 2001-11-03 2002-01-02 Astrazeneca Ab Compounds
ES2381781T3 (es) * 2002-02-01 2012-05-31 Astrazeneca Ab Compuestos de quinazolina
US7645878B2 (en) * 2002-03-22 2010-01-12 Bayer Healthcare Llc Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
DK1499311T3 (da) * 2002-03-29 2010-03-08 Novartis Vaccines & Diagnostic Substituerede benzaboler og anvendelse deraf som RAF-kinaseinhibitorer
AU2003257666A1 (en) * 2002-08-23 2004-03-11 Kirin Beer Kabushiki Kaisha COMPOUND HAVING TGFss INHIBITORY ACTIVITY AND MEDICINAL COMPOSITION CONTAINING THE SAME
US7320989B2 (en) * 2003-02-28 2008-01-22 Encysive Pharmaceuticals, Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
JP2006519258A (ja) * 2003-02-28 2006-08-24 エンサイシブ・ファーマシューティカルズ・インコーポレイテッド ピリジン、ピリミジン、キノリン、キナゾリンおよびナフタレン系のウロテンシン−ｉｉ受容体拮抗薬
US7531553B2 (en) * 2003-03-21 2009-05-12 Amgen Inc. Heterocyclic compounds and methods of use
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
US7312330B2 (en) * 2003-12-24 2007-12-25 Renovis, Inc. Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
JO2787B1 (en) * 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070891A2 (en) * 2004-01-23 2005-08-04 Amgen Inc Compounds and methods of use

Also Published As

Publication number Publication date
EP2220078B1 (en) 2013-05-22
MX2010004620A (es) 2010-07-28
AU2008319366A1 (en) 2009-05-07
JP2011502147A (ja) 2011-01-20
CA2703257A1 (en) 2009-05-07
WO2009058267A3 (en) 2010-06-10
JP5343082B2 (ja) 2013-11-13
US20090149454A1 (en) 2009-06-11
US7795254B2 (en) 2010-09-14
ES2417009T3 (es) 2013-08-05
WO2009058267A2 (en) 2009-05-07
EP2220078A2 (en) 2010-08-25
CA2703257C (en) 2013-02-19

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Legal Events

Date Code Title Description
DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTOR TO READ PAYACK, JOSEPH F.; SUBRAMANIAN, RAJU; MARTIN, MATTHEW W.; TEFFERA, YOHANNES; LARROW, JAY; ZANON, ROGER; DILMEGHANI SERAN, MINA; HARMANGE, JEAN-CHRISTOPHE AND WHITE, RYAN.

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTORS TO READ WHITE, RYAN; PAYACK, JOSEPH F.; LARROW, JAY; TEFFERA, YOHANNES; HARMANGE, JEAN-CHRISTOPHE; DILMEGHANI SERAN, MINA; SUBRAMANIAN, RAJU; ZANON, ROGER AND MARTIN, MATTHEW W.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired