AU2008258597A1 - New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission - Google Patents

New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission Download PDF

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Publication number
AU2008258597A1
AU2008258597A1 AU2008258597A AU2008258597A AU2008258597A1 AU 2008258597 A1 AU2008258597 A1 AU 2008258597A1 AU 2008258597 A AU2008258597 A AU 2008258597A AU 2008258597 A AU2008258597 A AU 2008258597A AU 2008258597 A1 AU2008258597 A1 AU 2008258597A1
Authority
AU
Australia
Prior art keywords
disorder
compound
stereoisomers
difluorophenyl
pyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008258597A
Other languages
English (en)
Inventor
Fredrik Pettersson
Clas Sonesson
Lars Swanson
Nicholas Waters
Susanna Waters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NSAB Filial af Neurosearch Sweden AB
Original Assignee
NSAB Filial af Neurosearch Sweden AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NSAB Filial af Neurosearch Sweden AB filed Critical NSAB Filial af Neurosearch Sweden AB
Publication of AU2008258597A1 publication Critical patent/AU2008258597A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pyrrole Compounds (AREA)
AU2008258597A 2007-06-05 2008-06-04 New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission Abandoned AU2008258597A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US94199307P 2007-06-05 2007-06-05
US60/941,993 2007-06-05
SE0701386 2007-06-05
SE0701386-5 2007-06-05
PCT/EP2008/056912 WO2008148799A1 (en) 2007-06-05 2008-06-04 New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission

Publications (1)

Publication Number Publication Date
AU2008258597A1 true AU2008258597A1 (en) 2008-12-11

Family

ID=39672106

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008258597A Abandoned AU2008258597A1 (en) 2007-06-05 2008-06-04 New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission

Country Status (11)

Country Link
US (1) US20100197760A1 (enExample)
EP (1) EP2155669B1 (enExample)
JP (1) JP2010529080A (enExample)
CN (1) CN101711234A (enExample)
AT (1) ATE508110T1 (enExample)
AU (1) AU2008258597A1 (enExample)
CA (1) CA2689692A1 (enExample)
DE (1) DE602008006720D1 (enExample)
MX (1) MX2009012716A (enExample)
NZ (1) NZ581363A (enExample)
WO (1) WO2008148799A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0812740A2 (pt) 2007-06-05 2016-07-19 Nsab Af Neurosearch Sweden Ab composto, composição farmacêutica, uso do composto, e, método para tratamento, prevenção ou alívio de um distúrbio do sistema nervoso central de um corpo de animal vivo.
ES2402713T3 (es) 2008-11-24 2013-05-08 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Derivados de 3-fenilo-3-metoxipirrolidina como moduladores de la transmisión catecolaminérgica cortical
AU2009317155A1 (en) 2008-11-24 2010-05-27 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Novel 3-phenyl-azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
CN103459563B (zh) * 2011-03-31 2015-06-17 雪佛龙美国公司 用于改进脱蜡催化剂稳定性和润滑油产率的新型方法和催化剂体系

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US364414A (en) * 1887-06-07 Gael hollweg
US2878264A (en) * 1959-03-17 Substituted amino alcohols
US3118907A (en) * 1961-08-14 1964-01-21 Mead Johnson & Co 3-substituted-3-pyrrolidinols
US3647790A (en) * 1969-04-08 1972-03-07 American Home Prod Ouinoxalinyl-oxazolidines and -oxazines
ES2157204T3 (es) 1991-04-17 2001-08-16 Upjohn Co Derivados de (s)-3-fenilpiperidina sustituidos, su preparacion y uso como antagonistas de autorreceptores de dopamina.
US5129962A (en) * 1991-10-22 1992-07-14 International Business Machines Corporation Tacky, no-clean thermally dissipated soldering flux
US20020169155A1 (en) * 1998-09-04 2002-11-14 Millennium Pharmaceuticals, Inc. Chemokine receptor anagonists and methods of use therefor
SE9904724D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
TWI308976B (en) * 2003-02-14 2009-04-21 Chunghwa Picture Tubes Ltd Process and structure of linquid crystal panel with one drop fill
GEP20084393B (en) * 2003-04-24 2008-06-10 Incyte Corp Aza spiro alkane derivatives as inhibitors of metalloproteases
CA2551037A1 (en) * 2003-09-22 2005-03-31 Banyu Pharmaceutical Co., Ltd. Novel piperidine derivative
TWI350168B (en) * 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
KR100690854B1 (ko) * 2005-11-08 2007-03-09 엘지전자 주식회사 멀티태스킹이 가능한 휴대용 단말기 및 그의 멀티태스킹처리방법
CN101341135B (zh) * 2005-12-21 2013-08-14 詹森药业有限公司 治疗mch-1介导的疾病的取代的吡嗪酮衍生物
US20080070649A1 (en) * 2006-09-06 2008-03-20 Uchida Toshi K Free Space Optical Interconnections in Cellular Telephone Handsets

Also Published As

Publication number Publication date
US20100197760A1 (en) 2010-08-05
ATE508110T1 (de) 2011-05-15
WO2008148799A1 (en) 2008-12-11
EP2155669B1 (en) 2011-05-04
CN101711234A (zh) 2010-05-19
MX2009012716A (es) 2009-12-14
EP2155669A1 (en) 2010-02-24
CA2689692A1 (en) 2008-12-11
NZ581363A (en) 2011-10-28
DE602008006720D1 (de) 2011-06-16
JP2010529080A (ja) 2010-08-26

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application