AU2008247352A1 - Elimination of interference in immunoassays caused by anti-carbohydrate antibodies - Google Patents

Elimination of interference in immunoassays caused by anti-carbohydrate antibodies Download PDF

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Publication number
AU2008247352A1
AU2008247352A1 AU2008247352A AU2008247352A AU2008247352A1 AU 2008247352 A1 AU2008247352 A1 AU 2008247352A1 AU 2008247352 A AU2008247352 A AU 2008247352A AU 2008247352 A AU2008247352 A AU 2008247352A AU 2008247352 A1 AU2008247352 A1 AU 2008247352A1
Authority
AU
Australia
Prior art keywords
assay
antibody
carbohydrate moiety
carbohydrate
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008247352A
Other languages
English (en)
Inventor
Michel Awwad
David Leroy Wensel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2008247352A1 publication Critical patent/AU2008247352A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008247352A 2007-05-07 2008-05-06 Elimination of interference in immunoassays caused by anti-carbohydrate antibodies Abandoned AU2008247352A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US92814407P 2007-05-07 2007-05-07
US60/928,144 2007-05-07
US92843807P 2007-05-08 2007-05-08
US60/928,438 2007-05-08
PCT/US2008/062739 WO2008137885A1 (en) 2007-05-07 2008-05-06 Elimination of interference in immunoassays caused by anti-carbohydrate antibodies

Publications (1)

Publication Number Publication Date
AU2008247352A1 true AU2008247352A1 (en) 2008-11-13

Family

ID=39666131

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008247352A Abandoned AU2008247352A1 (en) 2007-05-07 2008-05-06 Elimination of interference in immunoassays caused by anti-carbohydrate antibodies

Country Status (11)

Country Link
EP (1) EP2142925A1 (es)
JP (1) JP2010527005A (es)
KR (1) KR20100029083A (es)
CN (1) CN101680880A (es)
AU (1) AU2008247352A1 (es)
BR (1) BRPI0811290A2 (es)
CA (1) CA2686206A1 (es)
IL (1) IL201907A0 (es)
MX (2) MX2009012048A (es)
RU (1) RU2009141159A (es)
WO (1) WO2008137885A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102884433A (zh) 2010-04-29 2013-01-16 塞拉蒂亚戈公司 用于检测抗体的方法
EP3105592B1 (en) * 2014-02-11 2018-10-17 Genzyme Corporation Assays for detecting the presence or amount of an anti-drug antibody
EP3176580A1 (en) * 2015-12-01 2017-06-07 Roche Diagnostics GmbH Method for reduction of interferences in immunoassays
GB201522839D0 (en) * 2015-12-23 2016-02-03 Randox Lab Ltd And Randox Teoranta Method
MX2018016413A (es) * 2016-06-23 2019-05-09 Ablynx Nv Ensayos farmacocineticos mejorados para dominios variables unicos de inmunoglobulina.
CN108535490A (zh) * 2017-03-06 2018-09-14 苏州和锐生物科技有限公司 生物制剂血药浓度检测方法及试剂
AU2019301614A1 (en) 2018-07-10 2020-10-22 Regeneron Pharmaceuticals, Inc. Methods for mitigating drug target interference in an anti-drug antibody (ADA) immunoassay
CN113514632B (zh) * 2021-04-20 2024-06-25 中国科学技术大学 基于纳米抗体的微悬臂梁免疫传感方法
WO2023204378A1 (ko) * 2022-04-19 2023-10-26 의료법인 성광의료재단 혈액 내 항-약물항체 농도 측정을 통한 생물학적 약물에 대한 치료 반응성 예측 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705353A (en) * 1995-06-07 1998-01-06 Beckman Instruments, Inc. Method of reducing interferences in assays
US5856106A (en) * 1995-11-01 1999-01-05 Biotransplant, Inc. Determination of antibody production against administered therapeutic glycoproteins, especially monoclonal antibodies

Also Published As

Publication number Publication date
MX2009012048A (es) 2010-02-24
JP2010527005A (ja) 2010-08-05
KR20100029083A (ko) 2010-03-15
CN101680880A (zh) 2010-03-24
WO2008137885A1 (en) 2008-11-13
EP2142925A1 (en) 2010-01-13
BRPI0811290A2 (pt) 2014-10-21
MX2009012044A (es) 2009-11-18
IL201907A0 (en) 2010-06-16
RU2009141159A (ru) 2011-06-20
CA2686206A1 (en) 2008-11-13

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period