AU2007286454A1 - Crystal form of epothilone B and use in pharmaceutical compositions - Google Patents

Crystal form of epothilone B and use in pharmaceutical compositions Download PDF

Info

Publication number
AU2007286454A1
AU2007286454A1 AU2007286454A AU2007286454A AU2007286454A1 AU 2007286454 A1 AU2007286454 A1 AU 2007286454A1 AU 2007286454 A AU2007286454 A AU 2007286454A AU 2007286454 A AU2007286454 A AU 2007286454A AU 2007286454 A1 AU2007286454 A1 AU 2007286454A1
Authority
AU
Australia
Prior art keywords
epothilone
crystal form
medium
treatment
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007286454A
Other languages
English (en)
Inventor
Ernst Kusters
Michael Mutz
Frank Stowasser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37685905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2007286454(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2007286454A1 publication Critical patent/AU2007286454A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2007286454A 2006-08-16 2007-08-14 Crystal form of epothilone B and use in pharmaceutical compositions Abandoned AU2007286454A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06119043 2006-08-16
EP06119043.5 2006-08-16
PCT/EP2007/007173 WO2008019820A2 (en) 2006-08-16 2007-08-14 Crystal form of epothilone b and use in pharmaceutical compositions

Publications (1)

Publication Number Publication Date
AU2007286454A1 true AU2007286454A1 (en) 2008-02-21

Family

ID=37685905

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007286454A Abandoned AU2007286454A1 (en) 2006-08-16 2007-08-14 Crystal form of epothilone B and use in pharmaceutical compositions

Country Status (22)

Country Link
US (1) US8178566B2 (enExample)
EP (1) EP2064216A2 (enExample)
JP (1) JP2010500387A (enExample)
KR (1) KR20090038902A (enExample)
CN (1) CN101506217B (enExample)
AR (1) AR062375A1 (enExample)
AU (1) AU2007286454A1 (enExample)
BR (1) BRPI0715963A2 (enExample)
CA (1) CA2658475A1 (enExample)
CL (1) CL2007002362A1 (enExample)
IL (1) IL196558A0 (enExample)
MA (1) MA30656B1 (enExample)
MX (1) MX2009001635A (enExample)
MY (1) MY148355A (enExample)
NO (1) NO20091081L (enExample)
NZ (1) NZ574194A (enExample)
PE (1) PE20081317A1 (enExample)
RU (1) RU2009109352A (enExample)
TN (1) TN2009000044A1 (enExample)
TW (1) TW200815455A (enExample)
WO (1) WO2008019820A2 (enExample)
ZA (1) ZA200900227B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011146638A1 (en) 2010-05-18 2011-11-24 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
CN103910742B (zh) * 2013-01-07 2016-07-13 浙江海正药业股份有限公司 一种制备埃博霉素b无定形粉末的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1052974B1 (en) 1998-02-05 2009-05-20 Novartis AG Pharmaceutical formulation containing epothilone
US6194181B1 (en) * 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
UA75365C2 (en) * 2000-08-16 2006-04-17 Bristol Myers Squibb Co Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon
GB0029895D0 (en) 2000-12-07 2001-01-24 Novartis Ag Organic compounds
BRPI0314133A8 (pt) * 2002-09-23 2017-09-19 Bristol Myers Squibb Co Processo para isolamento de epotilona b, métodos para cultivo de microorganismo que produza epotilona a ou b e para purifiação de apotilona

Also Published As

Publication number Publication date
CL2007002362A1 (es) 2008-08-08
MY148355A (en) 2013-03-29
CN101506217B (zh) 2012-09-05
WO2008019820A3 (en) 2008-04-17
IL196558A0 (en) 2009-11-18
TN2009000044A1 (en) 2010-08-19
US8178566B2 (en) 2012-05-15
WO2008019820A2 (en) 2008-02-21
NO20091081L (no) 2009-03-16
AR062375A1 (es) 2008-11-05
BRPI0715963A2 (pt) 2013-08-06
KR20090038902A (ko) 2009-04-21
JP2010500387A (ja) 2010-01-07
CN101506217A (zh) 2009-08-12
NZ574194A (en) 2011-12-22
PE20081317A1 (es) 2008-10-28
TW200815455A (en) 2008-04-01
MA30656B1 (fr) 2009-08-03
CA2658475A1 (en) 2008-02-21
RU2009109352A (ru) 2010-09-27
US20100160393A1 (en) 2010-06-24
EP2064216A2 (en) 2009-06-03
ZA200900227B (en) 2009-12-30
MX2009001635A (es) 2009-02-23

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted