AU2007261561B2 - Regulation of protein activity by reversible acetylation - Google Patents

Regulation of protein activity by reversible acetylation Download PDF

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Publication number
AU2007261561B2
AU2007261561B2 AU2007261561A AU2007261561A AU2007261561B2 AU 2007261561 B2 AU2007261561 B2 AU 2007261561B2 AU 2007261561 A AU2007261561 A AU 2007261561A AU 2007261561 A AU2007261561 A AU 2007261561A AU 2007261561 B2 AU2007261561 B2 AU 2007261561B2
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AU
Australia
Prior art keywords
acecs2
polypeptide
sirt3
activity
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007261561A
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English (en)
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AU2007261561A1 (en
Inventor
Bjoern Schwer
Eric Verdin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J David Gladstone Institutes
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J David Gladstone Institutes
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Publication date
Application filed by J David Gladstone Institutes filed Critical J David Gladstone Institutes
Publication of AU2007261561A1 publication Critical patent/AU2007261561A1/en
Application granted granted Critical
Publication of AU2007261561B2 publication Critical patent/AU2007261561B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2007261561A 2006-06-12 2007-06-12 Regulation of protein activity by reversible acetylation Ceased AU2007261561B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US81327506P 2006-06-12 2006-06-12
US60/813,275 2006-06-12
US11/761,198 2007-06-11
US11/761,198 US8518635B2 (en) 2006-06-12 2007-06-11 Regulation of protein activity by reversible acetylation
PCT/US2007/013804 WO2007149270A2 (en) 2006-06-12 2007-06-12 Regulation of protein activity by reversible acetylation

Publications (2)

Publication Number Publication Date
AU2007261561A1 AU2007261561A1 (en) 2007-12-27
AU2007261561B2 true AU2007261561B2 (en) 2013-02-28

Family

ID=38833973

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007261561A Ceased AU2007261561B2 (en) 2006-06-12 2007-06-12 Regulation of protein activity by reversible acetylation

Country Status (8)

Country Link
US (1) US8518635B2 (https=)
EP (1) EP2029731B1 (https=)
JP (1) JP2009542195A (https=)
AT (1) ATE543902T1 (https=)
AU (1) AU2007261561B2 (https=)
CA (1) CA2654458A1 (https=)
ES (1) ES2380248T3 (https=)
WO (1) WO2007149270A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004022580A2 (en) 2002-09-09 2004-03-18 Dana-Farber Cancer Institute, Inc. Bh3 peptides and method of use thereof
EP2008106A2 (en) 2006-03-31 2008-12-31 Dana-Farber Cancer Institute Methods of determining cellular chemosensitivity
HK1213046A1 (zh) 2012-09-19 2016-06-24 Dana-Farber Cancer Institute, Inc. 動態bh3分析
CA2922503C (en) 2013-09-19 2021-10-26 Dana-Farber Cancer Institute, Inc. Methods of bh3 profiling
AU2016253957C1 (en) 2015-04-27 2021-04-01 Dana-Farber Cancer Institute, Inc. High throughput BH3 profiling: a rapid and scalable technology to BH3 profile on low numbers of cells
JP7589159B2 (ja) 2019-02-26 2024-11-25 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド ライブセルイメージング（ｌｉｖｅ ｃｅｌｌ ｉｍａｇｉｎｇ）動的ＢＨ３プロファイリング
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US82668A (en) * 1868-09-29 Thomas b
US120008A (en) * 1871-10-17 Improvement in apparatus for feeding pulverized fuel to metallurgical and other furnaces
JP2001149081A (ja) 1999-11-29 2001-06-05 Cyclex Co Ltd 脱アセチル化酵素の活性測定方法、並びにこれら酵素の阻害剤もしくは促進剤のスクリーニング方法
US20020120008A1 (en) 2000-06-29 2002-08-29 Seymour Benzer Life extension of drosophila by a drug treatment
US7241743B2 (en) 2001-06-15 2007-07-10 The Trustees Of Columbia University In The City Of New York Sir2α-based therapeutic and prophylactic methods
US7488587B2 (en) 2001-06-19 2009-02-10 The J. David Gladstone Institutes Histone deacetylase and methods of use thereof
CA2453195A1 (en) 2001-07-06 2003-01-16 Leonard Guarente Sir2 activity
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
CA2417033A1 (en) 2003-01-23 2004-07-23 Paul Kerr External support structure for use in the transporting of manufactured houses
US7272713B1 (en) 2003-10-22 2007-09-18 Symantec Corporation Controlling file operations
US7485416B2 (en) 2003-12-23 2009-02-03 The Regents Of The University Of California Screening methods for the identification of agents that inhibit SIRT1 Tat deacetylase activity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHWER, B., et al., Proceedings of the National Academy of Science, USA., 2006, vol. 103, pages 10224-10229 *

Also Published As

Publication number Publication date
US8518635B2 (en) 2013-08-27
WO2007149270A9 (en) 2008-03-06
US20090061015A1 (en) 2009-03-05
EP2029731A4 (en) 2009-10-21
WO2007149270A2 (en) 2007-12-27
WO2007149270A3 (en) 2008-10-30
JP2009542195A (ja) 2009-12-03
CA2654458A1 (en) 2007-12-27
EP2029731B1 (en) 2012-02-01
AU2007261561A1 (en) 2007-12-27
EP2029731A2 (en) 2009-03-04
ATE543902T1 (de) 2012-02-15
ES2380248T3 (es) 2012-05-09

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired