AU2006342024A1 - Tetracyclic kinase inhibitors - Google Patents

Tetracyclic kinase inhibitors Download PDF

Info

Publication number
AU2006342024A1
AU2006342024A1 AU2006342024A AU2006342024A AU2006342024A1 AU 2006342024 A1 AU2006342024 A1 AU 2006342024A1 AU 2006342024 A AU2006342024 A AU 2006342024A AU 2006342024 A AU2006342024 A AU 2006342024A AU 2006342024 A1 AU2006342024 A1 AU 2006342024A1
Authority
AU
Australia
Prior art keywords
alkyl
compound
amino
carbocycle
heterocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006342024A
Other languages
English (en)
Inventor
Ignacio Aliagas-Martin
Thomas E. Rawson
Brian Safina
Bing-Yan Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of AU2006342024A1 publication Critical patent/AU2006342024A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D497/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2006342024A 2005-12-16 2006-12-14 Tetracyclic kinase inhibitors Abandoned AU2006342024A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75123405P 2005-12-16 2005-12-16
US60/751,234 2005-12-16
PCT/US2006/062112 WO2007120333A2 (en) 2005-12-16 2006-12-14 Tetracyclic kinase inhibitors

Publications (1)

Publication Number Publication Date
AU2006342024A1 true AU2006342024A1 (en) 2007-10-25

Family

ID=38610005

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006342024A Abandoned AU2006342024A1 (en) 2005-12-16 2006-12-14 Tetracyclic kinase inhibitors

Country Status (6)

Country Link
US (1) US20090131407A1 (https=)
EP (1) EP1968581A4 (https=)
JP (1) JP2009519974A (https=)
AU (1) AU2006342024A1 (https=)
CA (1) CA2631871A1 (https=)
WO (1) WO2007120333A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090203671A1 (en) * 2007-11-27 2009-08-13 Abbott Laboratories Method of treating cancer
US8716308B2 (en) 2008-01-11 2014-05-06 Albany Molecular Research, Inc. (1-azinone)-substituted pyridoindoles
MX2010008700A (es) 2008-02-22 2010-08-30 Hoffmann La Roche Moduladores de beta-amiloide.
WO2010039187A2 (en) * 2008-09-23 2010-04-08 University Of Maryland, Baltimore County Fused diimidazodiazepine compounds and methods of use and manufacture thereof
ES2429517T3 (es) 2008-10-09 2013-11-15 F. Hoffmann-La Roche Ag Moduladores para la beta amiloide
CN102209537A (zh) 2008-11-10 2011-10-05 弗·哈夫曼-拉罗切有限公司 杂环γ分泌酶调节剂
US8629158B2 (en) 2009-07-01 2014-01-14 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US8637501B2 (en) 2009-07-01 2014-01-28 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
US8486967B2 (en) 2010-02-17 2013-07-16 Hoffmann-La Roche Inc. Heteroaryl substituted piperidines
WO2012088038A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
CN106674081A (zh) * 2016-12-18 2017-05-17 南京理工大学 一种3‑甲硫基吲哚衍生物合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3772325A (en) * 1972-03-24 1973-11-13 American Cyanamid Co Novel hexahydro cyclohept(b)indoles
EP1127051A2 (en) * 1998-11-06 2001-08-29 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
BRPI0407544A (pt) * 2003-02-17 2006-02-14 Pharmacia Italia Spa derivados de pirazol tetracìclicos como inibidores da cinase, processo para a sua preparação e composições farmacêuticas que os compreendem
US20050032869A1 (en) * 2003-07-08 2005-02-10 Pharmacia Italia S.P.A. Pyrazolyl-indole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
US20070254877A1 (en) * 2004-06-02 2007-11-01 Takada Pharmaceutical Company Limited Indole Derivative and Use for Treatment of Cancer

Also Published As

Publication number Publication date
EP1968581A2 (en) 2008-09-17
CA2631871A1 (en) 2007-10-25
US20090131407A1 (en) 2009-05-21
WO2007120333A2 (en) 2007-10-25
JP2009519974A (ja) 2009-05-21
WO2007120333A3 (en) 2008-01-10
EP1968581A4 (en) 2009-05-27

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: ADD CI-INVENTOR NAME TO READ ALIAGAS-MARTIN, IGNACIO

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application