AU2006324872B2 - Pharmaceutical composition comprising at least one anticancer drug and at least one polymer - Google Patents
Pharmaceutical composition comprising at least one anticancer drug and at least one polymer Download PDFInfo
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- AU2006324872B2 AU2006324872B2 AU2006324872A AU2006324872A AU2006324872B2 AU 2006324872 B2 AU2006324872 B2 AU 2006324872B2 AU 2006324872 A AU2006324872 A AU 2006324872A AU 2006324872 A AU2006324872 A AU 2006324872A AU 2006324872 B2 AU2006324872 B2 AU 2006324872B2
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- Australia
- Prior art keywords
- composition
- drug
- composition according
- paclitaxel
- particles
- Prior art date
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- HNMATTJJEPZZMM-BPKVFSPJSA-N s-[(2r,3s,4s,6s)-6-[[(2r,3s,4s,5r,6r)-5-[(2s,4s,5s)-5-[acetyl(ethyl)amino]-4-methoxyoxan-2-yl]oxy-6-[[(2s,5z,9r,13e)-13-[2-[[4-[(2e)-2-[1-[4-(4-amino-4-oxobutoxy)phenyl]ethylidene]hydrazinyl]-2-methyl-4-oxobutan-2-yl]disulfanyl]ethylidene]-9-hydroxy-12-(m Chemical compound C1[C@H](OC)[C@@H](N(CC)C(C)=O)CO[C@H]1O[C@H]1[C@H](O[C@@H]2C\3=C(NC(=O)OC)C(=O)C[C@@](C/3=C/CSSC(C)(C)CC(=O)N\N=C(/C)C=3C=CC(OCCCC(N)=O)=CC=3)(O)C#C\C=C/C#C2)O[C@H](C)[C@@H](NO[C@@H]2O[C@H](C)[C@@H](SC(=O)C=3C(=C(OC)C(O[C@H]4[C@@H]([C@H](OC)[C@@H](O)[C@H](C)O4)O)=C(I)C=3C)OC)[C@@H](O)C2)[C@@H]1O HNMATTJJEPZZMM-BPKVFSPJSA-N 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 108010038379 sargramostim Proteins 0.000 description 1
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- 238000013341 scale-up Methods 0.000 description 1
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- 210000002863 seminiferous tubule Anatomy 0.000 description 1
- 229960003440 semustine Drugs 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000002047 solid lipid nanoparticle Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
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- 230000001360 synchronised effect Effects 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
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- 230000009897 systematic effect Effects 0.000 description 1
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- 150000004579 taxol derivatives Chemical class 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
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- 230000004797 therapeutic response Effects 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
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- 230000000699 topical effect Effects 0.000 description 1
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- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1327MU2005 | 2005-10-21 | ||
| IN1327/MUM/2005 | 2005-10-21 | ||
| IN1081/MUM/2006 | 2006-07-10 | ||
| IN1081MU2006 | 2006-07-10 | ||
| PCT/IN2006/000427 WO2007069272A2 (en) | 2005-10-21 | 2006-10-19 | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
Publications (2)
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| AU2006324872A1 AU2006324872A1 (en) | 2007-06-21 |
| AU2006324872B2 true AU2006324872B2 (en) | 2012-03-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006324872A Expired - Fee Related AU2006324872B2 (en) | 2005-10-21 | 2006-10-19 | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
Country Status (13)
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| US (1) | US20100166872A1 (enExample) |
| EP (1) | EP1962906A4 (enExample) |
| JP (1) | JP2009512682A (enExample) |
| AR (1) | AR058130A1 (enExample) |
| AU (1) | AU2006324872B2 (enExample) |
| BR (1) | BRPI0617663A2 (enExample) |
| CA (1) | CA2626016A1 (enExample) |
| CR (1) | CR9989A (enExample) |
| EA (1) | EA015781B1 (enExample) |
| IL (1) | IL190882A0 (enExample) |
| MA (1) | MA29946B1 (enExample) |
| RS (1) | RS20080167A (enExample) |
| WO (1) | WO2007069272A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2231144B1 (en) * | 2007-12-24 | 2014-07-02 | Sun Pharma Advanced Research Company Limited | Nanodispersion |
| US8865222B2 (en) | 2008-02-11 | 2014-10-21 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for enrichment of food and beverages and methods of preparation thereof |
| US8871276B2 (en) | 2008-02-11 | 2014-10-28 | Technion Research And Development Foundation Ltd. | Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents |
| EP2252266A1 (en) | 2008-02-11 | 2010-11-24 | Yissum Research Development Company of the Hebrew University of Jerusalem | Beta-casein assemblies for mucosal delivery of therapeutic bioactive agents |
| EP2252269A1 (en) * | 2008-02-11 | 2010-11-24 | Technion Research and Development Foundation, Ltd. | Casein particles encapsulating therapeutically active agents and uses thereof |
| GB0818747D0 (en) | 2008-10-13 | 2008-11-19 | Univ Nottingham | Biocompatible responsive materials |
| EP2266546A1 (en) | 2009-06-08 | 2010-12-29 | Advancell Advanced in Vitro Cell Technologies,S.A. | Process for the preparation of colloidal systems for the delivery of active compounds |
| EP2442805A4 (en) | 2009-06-19 | 2012-11-21 | Sun Pharma Advanced Res Co Ltd | NANODISPERSION OF A MEDICINE AND METHOD FOR PREPARING THE SAME |
| WO2011017835A1 (en) * | 2009-08-11 | 2011-02-17 | Nanjing University | Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding |
| CA2774669C (en) * | 2009-09-21 | 2017-12-19 | Jw Pharmaceutical Corporation | Oxaliplatin nanoparticles and method for preparing same |
| AU2011248449B2 (en) | 2010-05-03 | 2016-09-15 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| WO2011151722A2 (en) * | 2010-06-01 | 2011-12-08 | Geistlich Pharma Ag | Methods and compositions for oral pharmaceutical therapy |
| WO2012058462A2 (en) * | 2010-10-29 | 2012-05-03 | Isis Pharmaceuticals, Inc. | Combination therapy for the treatment of cancer |
| EP2645991B1 (en) | 2010-12-02 | 2020-02-12 | GreenMark Biomedical Inc. | Aptamer bioconjugate drug delivery device |
| ES2629187T3 (es) | 2011-04-20 | 2017-08-07 | The University Of Sydney | Material en forma de partículas y toxina celular para su uso en el tratamiento de un tumor sólido |
| US9364433B2 (en) | 2011-04-28 | 2016-06-14 | Borje S. Andersson | Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same |
| WO2013124867A1 (en) * | 2012-02-21 | 2013-08-29 | Amrita Vishwa Vidyapeetham University | Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules |
| MX367055B (es) | 2012-06-26 | 2019-08-02 | Del Mar Pharmaceuticals | El uso de una composición que comprende dianhidrogalactitol, diacetildianhidrogalactitol, y dibromodulcitol, y análogos o derivados de cada uno para el tratamiento de malignidades resistentes a inhibidores de tirosina cinasa. |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| US10143700B2 (en) | 2013-02-19 | 2018-12-04 | Amrita Vishwa Vidyapeetham | Nanoparticle formulations for delivering multiple therapeutic agents |
| CN105492011A (zh) | 2013-04-08 | 2016-04-13 | 丹尼斯·M·布朗 | 不理想给药化学化合物的治疗增效 |
| PL3046584T3 (pl) | 2013-09-16 | 2017-11-30 | Astrazeneca Ab | Terapeutyczne polimeryczne nanocząstki i sposoby ich wytwarzania i stosowania |
| KR20150047336A (ko) | 2013-10-24 | 2015-05-04 | 삼성전자주식회사 | 나노입자, 이를 제조하는 방법, 및 이의 용도 |
| HUP1300646A2 (en) | 2013-11-12 | 2015-05-28 | Druggability Technologies Ip Holdco Jersey Ltd | Complexes of fulvestrant and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
| CN103739672B (zh) * | 2013-12-31 | 2015-06-10 | 威特曼生物科技（南京）有限公司 | 一种聚乙二醇修饰的抑制vegfr2酪氨酸激酶多肽及其应用 |
| RU2591819C2 (ru) * | 2014-03-03 | 2016-07-20 | Закрытое акционерное общество "СКАЙ ЛТД" | Способ получения фолликулярного белкового препарата и препарат, полученный данным способом |
| HRP20251032T1 (hr) | 2015-02-01 | 2025-10-24 | Quetzal Therapeutics, Llc | Liofilizirani pripravci s visokim površinskim područjem koji sadrže arsen za oralnu primjenu kod pacijenata |
| EP3265059A4 (en) | 2015-03-03 | 2018-08-29 | Cureport Inc. | Combination liposomal pharmaceutical formulations |
| JP2018507227A (ja) | 2015-03-03 | 2018-03-15 | キュアポート インコーポレイテッド | 二薬搭載リポソーム医薬製剤 |
| CN106137969B (zh) | 2015-04-03 | 2020-05-15 | 四川科伦药物研究院有限公司 | 多西他赛白蛋白纳米粒药物组合物及其制备方法及应用 |
| IL285928B2 (en) | 2016-05-06 | 2025-06-01 | Eagle Pharmaceuticals Inc | Fulvestrant formulations and methods of their use |
| WO2018200393A1 (en) * | 2017-04-24 | 2018-11-01 | Zy Therapeutics Inc. | Pharmaceutical composition for in vivo delivery, method of preparation of a substantially waterinsoluble pharmacologically active agent |
| WO2019028457A2 (en) * | 2017-08-04 | 2019-02-07 | University Of Houston System | FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE |
| EP3773751A4 (en) | 2018-03-28 | 2021-12-01 | GreenMark Biomedical Inc. | PHOSPHATE CROSS-LINKED STARCH NANOPARTICLE AND DENTAL TREATMENTS |
| AU2019312592B2 (en) | 2018-07-31 | 2025-06-26 | Microbion Corporation | Bismuth-thiol compositions and methods for treating wounds |
| CA3107760A1 (en) | 2018-07-31 | 2020-02-06 | Microbion Corporation | Bismuth-thiol compositions and methods of use |
| FR3087650B1 (fr) * | 2018-10-31 | 2021-01-29 | Bio Even | Flavine adenine dinucleotide (fad) pour son utilisation pour la prevention et/ou le traitement de cancer |
| CN114767879A (zh) * | 2022-06-02 | 2022-07-22 | 平顶山学院 | 一种多西紫杉醇恶性肿瘤靶向微球及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2634397B2 (fr) * | 1986-12-31 | 1991-04-19 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules |
| US5766635A (en) * | 1991-06-28 | 1998-06-16 | Rhone-Poulenc Rorer S.A. | Process for preparing nanoparticles |
| WO1994026254A1 (en) * | 1993-05-17 | 1994-11-24 | The Liposome Company, Inc. | Incorporation of taxol into liposomes and gels |
| NZ502500A (en) * | 1997-06-27 | 2002-03-28 | Vivorx Pharmaceuticals Inc | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| AU784416B2 (en) * | 1999-05-21 | 2006-03-30 | Abraxis Bioscience, Llc | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| WO2001049268A1 (en) * | 2000-01-05 | 2001-07-12 | Imarx Therapeutics, Inc. | Pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
| ITMI20001107A1 (it) * | 2000-05-18 | 2001-11-18 | Acs Dobfar Spa | Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel |
| JP2006508126A (ja) * | 2002-11-06 | 2006-03-09 | アザヤ セラピューティクス インコーポレイティッド | 薬学的製剤のタンパク質安定化されたリポソーム製剤 |
| KR20110079741A (ko) * | 2002-12-09 | 2011-07-07 | 아브락시스 바이오사이언스, 엘엘씨 | 약리학적 물질의 조성물 및 그 전달방법 |
-
2006
- 2006-10-19 WO PCT/IN2006/000427 patent/WO2007069272A2/en not_active Ceased
- 2006-10-19 CA CA002626016A patent/CA2626016A1/en not_active Abandoned
- 2006-10-19 JP JP2008536207A patent/JP2009512682A/ja active Pending
- 2006-10-19 AU AU2006324872A patent/AU2006324872B2/en not_active Expired - Fee Related
- 2006-10-19 US US12/083,594 patent/US20100166872A1/en not_active Abandoned
- 2006-10-19 EA EA200801132A patent/EA015781B1/ru not_active IP Right Cessation
- 2006-10-19 RS RSP-2008/0167A patent/RS20080167A/sr unknown
- 2006-10-19 EP EP06847315A patent/EP1962906A4/en not_active Withdrawn
- 2006-10-19 BR BRPI0617663-1A patent/BRPI0617663A2/pt not_active IP Right Cessation
- 2006-10-20 AR ARP060104602A patent/AR058130A1/es unknown
-
2008
- 2008-04-15 IL IL190882A patent/IL190882A0/en unknown
- 2008-05-15 MA MA30925A patent/MA29946B1/fr unknown
- 2008-05-20 CR CR9989A patent/CR9989A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR9989A (es) | 2008-07-18 |
| US20100166872A1 (en) | 2010-07-01 |
| WO2007069272A3 (en) | 2007-08-23 |
| EP1962906A4 (en) | 2009-11-18 |
| EP1962906A2 (en) | 2008-09-03 |
| MA29946B1 (fr) | 2008-11-03 |
| EA015781B1 (ru) | 2011-12-30 |
| AU2006324872A1 (en) | 2007-06-21 |
| CA2626016A1 (en) | 2007-06-21 |
| WO2007069272A2 (en) | 2007-06-21 |
| RS20080167A (sr) | 2009-07-15 |
| AR058130A1 (es) | 2008-01-23 |
| JP2009512682A (ja) | 2009-03-26 |
| BRPI0617663A2 (pt) | 2011-08-02 |
| IL190882A0 (en) | 2008-11-03 |
| EA200801132A1 (ru) | 2009-02-27 |
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| Date | Code | Title | Description |
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| MK25 | Application lapsed reg. 22.2i(2) - failure to pay acceptance fee |