AU2006290475A1 - Pseudomonas exotoxin a CD4+ T-cell epitopes - Google Patents
Pseudomonas exotoxin a CD4+ T-cell epitopes Download PDFInfo
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- AU2006290475A1 AU2006290475A1 AU2006290475A AU2006290475A AU2006290475A1 AU 2006290475 A1 AU2006290475 A1 AU 2006290475A1 AU 2006290475 A AU2006290475 A AU 2006290475A AU 2006290475 A AU2006290475 A AU 2006290475A AU 2006290475 A1 AU2006290475 A1 AU 2006290475A1
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| AU2019301675B2 (en) | 2018-07-12 | 2025-09-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Affinity matured CD22-specific monoclonal antibody and uses thereof |
| US12012463B2 (en) | 2018-08-08 | 2024-06-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | High affinity monoclonal antibodies targeting glypican-2 and uses thereof |
| WO2020146182A1 (en) | 2019-01-08 | 2020-07-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cross-species single domain antibodies targeting mesothelin for treating solid tumors |
| WO2020154150A1 (en) | 2019-01-22 | 2020-07-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | High affinity monoclonal antibodies targeting glypican-1 and methods of use |
| CN119899265A (zh) | 2019-10-22 | 2025-04-29 | 美国政府(由卫生和人类服务部的部长所代表) | 用于治疗多种实体瘤的靶向b7h3（cd276）的高亲和力纳米抗体 |
| WO2022093745A1 (en) | 2020-10-26 | 2022-05-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Single domain antibodies targeting sars coronavirus spike protein and uses thereof |
| WO2022232612A1 (en) | 2021-04-29 | 2022-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Lassa virus-specific nanobodies and methods of their use |
| CA3216228A1 (en) | 2021-06-09 | 2022-12-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cross species single domain antibodies targeting pd-l1 for treating solid tumors |
| WO2023076881A1 (en) | 2021-10-26 | 2023-05-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Single domain antibodies targeting the s2 subunit of sars-cov-2 spike protein |
| WO2024050399A1 (en) | 2022-09-01 | 2024-03-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes |
| WO2024104584A1 (en) | 2022-11-17 | 2024-05-23 | University Of Cape Town | Deimmunized pseudomonas exotoxin a |
| WO2024238346A1 (en) | 2023-05-12 | 2024-11-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Single domain antibodies that specifically bind the s2 subunit of sars-cov-2 spike protein and compositions and uses thereof |
| WO2025019228A1 (en) | 2023-07-20 | 2025-01-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment of solid tumors |
| WO2025171238A1 (en) | 2024-02-07 | 2025-08-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Monoclonal antibodies that bind the juxta-membrane region of mesothelin and uses thereof |
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| US5458878A (en) * | 1990-01-02 | 1995-10-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | P. exotoxin fusio proteins have COOHG220101al alterations which increase cytotoxicity |
| US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
| CA2461351C (en) * | 2001-09-26 | 2014-08-05 | Ira H. Pastan | Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells |
| WO2005052006A2 (en) * | 2003-11-25 | 2005-06-09 | The Government Of The United States, As Represented By The Secretary Of Health And Human Services | Mutated anti-cd22 antibodies and immunoconjugates |
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2006
- 2006-09-12 JP JP2008530608A patent/JP2009511000A/ja active Pending
- 2006-09-12 CA CA002622525A patent/CA2622525A1/en not_active Abandoned
- 2006-09-12 AU AU2006290475A patent/AU2006290475A1/en not_active Abandoned
- 2006-09-12 US US12/066,709 patent/US20080193976A1/en not_active Abandoned
- 2006-09-12 EP EP06779398A patent/EP1922330A1/en not_active Withdrawn
- 2006-09-12 WO PCT/GB2006/003384 patent/WO2007031741A1/en not_active Ceased
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2010
- 2010-08-02 US US12/848,387 patent/US20100291150A1/en not_active Abandoned
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| US20100291150A1 (en) | 2010-11-18 |
| US20080193976A1 (en) | 2008-08-14 |
| WO2007031741A1 (en) | 2007-03-22 |
| JP2009511000A (ja) | 2009-03-19 |
| CA2622525A1 (en) | 2007-03-22 |
| EP1922330A1 (en) | 2008-05-21 |
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