AU2006279218B2 - Reducing post-operative adhesion formation with intraperitoneal glutamine - Google Patents

Reducing post-operative adhesion formation with intraperitoneal glutamine Download PDF

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Publication number
AU2006279218B2
AU2006279218B2 AU2006279218A AU2006279218A AU2006279218B2 AU 2006279218 B2 AU2006279218 B2 AU 2006279218B2 AU 2006279218 A AU2006279218 A AU 2006279218A AU 2006279218 A AU2006279218 A AU 2006279218A AU 2006279218 B2 AU2006279218 B2 AU 2006279218B2
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AU
Australia
Prior art keywords
glutamine
composition
source
adhesion formation
alanyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2006279218A
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English (en)
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AU2006279218A1 (en
Inventor
Adebola O.E. Obayan
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ADETHERAPEUTICS Inc
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ADETHERAPEUTICS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ADETHERAPEUTICS Inc filed Critical ADETHERAPEUTICS Inc
Publication of AU2006279218A1 publication Critical patent/AU2006279218A1/en
Priority to AU2013204912A priority Critical patent/AU2013204912B2/en
Priority to AU2013204918A priority patent/AU2013204918A1/en
Application granted granted Critical
Publication of AU2006279218B2 publication Critical patent/AU2006279218B2/en
Assigned to ADETHERAPEUTICS, INC. reassignment ADETHERAPEUTICS, INC. Request for Assignment Assignors: UNIVERSITY OF SASKATCHEWAN
Priority to AU2016266102A priority patent/AU2016266102B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A61L2300/214—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/424—Anti-adhesion agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
AU2006279218A 2005-08-11 2006-08-11 Reducing post-operative adhesion formation with intraperitoneal glutamine Expired AU2006279218B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2013204912A AU2013204912B2 (en) 2005-08-11 2013-04-12 Reducing post-operative adhesion formation with intraperitoneal glutamine
AU2013204918A AU2013204918A1 (en) 2005-08-11 2013-04-12 Reducing post-operative adhesion formation with intrapertoneal glutamine
AU2016266102A AU2016266102B2 (en) 2005-08-11 2016-12-02 Reducing post-operative adhesion formation with intraperitoneal glutamine

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70717305P 2005-08-11 2005-08-11
US60/707,173 2005-08-11
PCT/CA2006/001319 WO2007016791A1 (en) 2005-08-11 2006-08-11 Reducing post-operative adhesion formation with intraperitoneal glutamine

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2013204912A Division AU2013204912B2 (en) 2005-08-11 2013-04-12 Reducing post-operative adhesion formation with intraperitoneal glutamine
AU2013204918A Division AU2013204918A1 (en) 2005-08-11 2013-04-12 Reducing post-operative adhesion formation with intrapertoneal glutamine

Publications (2)

Publication Number Publication Date
AU2006279218A1 AU2006279218A1 (en) 2007-02-15
AU2006279218B2 true AU2006279218B2 (en) 2013-05-02

Family

ID=37727066

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Application Number Title Priority Date Filing Date
AU2006279218A Expired AU2006279218B2 (en) 2005-08-11 2006-08-11 Reducing post-operative adhesion formation with intraperitoneal glutamine

Country Status (14)

Country Link
US (5) US20100260819A1 (enExample)
EP (1) EP1940439B1 (enExample)
JP (1) JP5194207B2 (enExample)
AT (1) ATE485829T1 (enExample)
AU (1) AU2006279218B2 (enExample)
CA (1) CA2618600C (enExample)
CY (1) CY1112051T1 (enExample)
DE (1) DE602006017864D1 (enExample)
DK (1) DK1940439T3 (enExample)
ES (1) ES2355159T3 (enExample)
PL (1) PL1940439T3 (enExample)
PT (1) PT1940439E (enExample)
SI (1) SI1940439T1 (enExample)
WO (1) WO2007016791A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5194207B2 (ja) 2005-08-11 2013-05-08 エーディーイー、セラピューティックス、インコーポレーテッド 腹腔内グルタミンによる術後癒着形成の減少
CA2578647A1 (en) * 2007-02-15 2008-08-15 University Of Saskatchewan Reducing post-operative adhesion formation with intraperitoneal glutamine
US20100099628A1 (en) 2007-03-02 2010-04-22 Zyto-Protec Gmbh Carbohydrate-based peritoneal dialysis fluid comprising glutamine residue
EP2113262B1 (en) * 2008-04-29 2013-11-06 Proxy Biomedical Limited A Tissue Repair Implant
KR20130089174A (ko) * 2010-06-28 2013-08-09 에이드 테라퓨틱스 인코포레이티드 켈로이드 치료법
EP2839851A4 (en) 2012-08-16 2015-11-25 Nipro Corp STICK MATERIAL
PT3448421T (pt) * 2016-04-29 2022-01-14 Univ Leland Stanford Junior Métodos e composições para a prevenção e tratamento de aderências cirúrgicas
CN109789249B (zh) 2016-06-15 2022-01-25 土耳其科学技术研究理事会 多功能疝气贴片
US10500318B1 (en) * 2018-07-03 2019-12-10 Temple Therapeutics BV Dosing regimens for treating hypoxia-associated tissue damage
WO2022234489A1 (en) 2021-05-07 2022-11-10 Temple Therapeutics BV Methods of treating fibrosis and hypoxia-associated damage to peripheral nerves
WO2025163204A1 (en) 2024-02-01 2025-08-07 Temple Therapeutics BV Glutamine source for use in methods and compositions for reducing or preventing synovial joint adhesions or fibrosis

Citations (1)

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Publication number Priority date Publication date Assignee Title
CA2501540A1 (en) * 2002-10-08 2004-04-22 Abbott Laboratories Methods and compositions for providing glutamine

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Also Published As

Publication number Publication date
US20190111189A1 (en) 2019-04-18
PL1940439T3 (pl) 2011-04-29
JP5194207B2 (ja) 2013-05-08
US9011883B2 (en) 2015-04-21
AU2006279218A1 (en) 2007-02-15
SI1940439T1 (sl) 2011-02-28
WO2007016791A1 (en) 2007-02-15
DE602006017864D1 (de) 2010-12-09
PT1940439E (pt) 2010-12-17
US10799622B2 (en) 2020-10-13
JP2009504576A (ja) 2009-02-05
US20150250928A1 (en) 2015-09-10
HK1120223A1 (en) 2009-03-27
EP1940439B1 (en) 2010-10-27
DK1940439T3 (da) 2011-02-14
ES2355159T3 (es) 2011-03-23
WO2007016791A8 (en) 2008-09-18
ATE485829T1 (de) 2010-11-15
US20170203013A1 (en) 2017-07-20
US20130171209A1 (en) 2013-07-04
CA2618600A1 (en) 2007-02-15
CA2618600C (en) 2017-05-02
EP1940439A4 (en) 2009-07-08
EP1940439A1 (en) 2008-07-09
US20100260819A1 (en) 2010-10-14
CY1112051T1 (el) 2015-11-04

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE PRIORITY DETAILS TO READ 60/707,173 11 AUG 2005 US

PC1 Assignment before grant (sect. 113)

Owner name: ADETHERAPEUTICS, INC.

Free format text: FORMER APPLICANT(S): UNIVERSITY OF SASKATCHEWAN

FGA Letters patent sealed or granted (standard patent)