AU2006275424B2 - Method of preserving the function of insulin-producing cells - Google Patents

Method of preserving the function of insulin-producing cells Download PDF

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Publication number
AU2006275424B2
AU2006275424B2 AU2006275424A AU2006275424A AU2006275424B2 AU 2006275424 B2 AU2006275424 B2 AU 2006275424B2 AU 2006275424 A AU2006275424 A AU 2006275424A AU 2006275424 A AU2006275424 A AU 2006275424A AU 2006275424 B2 AU2006275424 B2 AU 2006275424B2
Authority
AU
Australia
Prior art keywords
insulin
patient
medicament
dose
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006275424A
Other languages
English (en)
Other versions
AU2006275424A1 (en
Inventor
Anders Hasager Boss
Wayman Wendell Cheatham
David C. Diamond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mannkind Corp
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of AU2006275424A1 publication Critical patent/AU2006275424A1/en
Application granted granted Critical
Publication of AU2006275424B2 publication Critical patent/AU2006275424B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2006275424A 2005-08-01 2006-08-01 Method of preserving the function of insulin-producing cells Ceased AU2006275424B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70429505P 2005-08-01 2005-08-01
US60/704,295 2005-08-01
PCT/US2006/030014 WO2007016600A2 (en) 2005-08-01 2006-08-01 Method of preserving the function of insulin-producing cells

Publications (2)

Publication Number Publication Date
AU2006275424A1 AU2006275424A1 (en) 2007-02-08
AU2006275424B2 true AU2006275424B2 (en) 2013-01-10

Family

ID=37561086

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006275424A Ceased AU2006275424B2 (en) 2005-08-01 2006-08-01 Method of preserving the function of insulin-producing cells

Country Status (10)

Country Link
EP (1) EP1915171B1 (https=)
JP (2) JP2009503093A (https=)
CN (1) CN101232899A (https=)
AU (1) AU2006275424B2 (https=)
BR (1) BRPI0614489A2 (https=)
CA (1) CA2617226A1 (https=)
DK (1) DK1915171T3 (https=)
ES (1) ES2439455T3 (https=)
MX (1) MX2008001643A (https=)
WO (1) WO2007016600A2 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2379100T3 (en) * 2009-01-08 2014-12-01 Mannkind Corp Treatment of hyperglycemia with GLP-1
CN102438602B (zh) * 2009-03-04 2016-04-13 曼金德公司 改进的干燥粉末药物输送系统
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3933845A3 (en) 2014-10-27 2022-06-22 Aseko, Inc. Subcutaneous outpatient management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
JP7109155B2 (ja) 2015-06-04 2022-07-29 キッコーマン株式会社 フラビン結合型グルコースデヒドロゲナーゼを用いたグルコースの測定方法
EP3337402B1 (en) 2015-08-20 2026-01-07 Glytec, LLC Diabetes management therapy advisor
CN110187123B (zh) * 2019-05-06 2022-07-22 天津医科大学总医院 一种糖尿病早期诊断生物标志物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000654A2 (en) * 1999-06-29 2001-01-04 Pharmaceutical Discovery Corporation Purification and stabilization of peptide and proteins in pharmaceutical agents
WO2005067964A1 (en) * 2004-01-12 2005-07-28 Mannkind Corporation A method of reducing serum proinsulin levels in type 2 diabetics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1259045A (zh) * 1997-04-02 2000-07-05 普渡研究基金会 蛋白质的口服释放方法
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
WO2004080401A2 (en) * 2003-03-06 2004-09-23 Emisphere Technologies, Inc. Oral insulin therapies and protocol

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000654A2 (en) * 1999-06-29 2001-01-04 Pharmaceutical Discovery Corporation Purification and stabilization of peptide and proteins in pharmaceutical agents
WO2005067964A1 (en) * 2004-01-12 2005-07-28 Mannkind Corporation A method of reducing serum proinsulin levels in type 2 diabetics

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Chase et al, Pediatric Diabetes, 2004, vol. 5, pages 16-19 *
Diez et al, Expert Opin. Pharmacother., 2003, vol. 4, pages 191-200 *
PFUETZNER A. et al: Program And Abstracts Of The Annual Meeting Of The European Association For The Study Of Diabetes, XX, XX, 9 September 2001, pages 1-2. *

Also Published As

Publication number Publication date
JP2009503093A (ja) 2009-01-29
BRPI0614489A2 (pt) 2011-03-29
WO2007016600A3 (en) 2007-05-31
CA2617226A1 (en) 2007-02-08
CN101232899A (zh) 2008-07-30
EP1915171B1 (en) 2013-11-20
DK1915171T3 (da) 2013-12-09
JP2015091854A (ja) 2015-05-14
EP1915171A2 (en) 2008-04-30
MX2008001643A (es) 2008-04-07
ES2439455T3 (es) 2014-01-23
AU2006275424A1 (en) 2007-02-08
WO2007016600A2 (en) 2007-02-08

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired