AU2005324199A1 - Taurine synthesis, production and utility as a medicine - Google Patents
Taurine synthesis, production and utility as a medicine Download PDFInfo
- Publication number
- AU2005324199A1 AU2005324199A1 AU2005324199A AU2005324199A AU2005324199A1 AU 2005324199 A1 AU2005324199 A1 AU 2005324199A1 AU 2005324199 A AU2005324199 A AU 2005324199A AU 2005324199 A AU2005324199 A AU 2005324199A AU 2005324199 A1 AU2005324199 A1 AU 2005324199A1
- Authority
- AU
- Australia
- Prior art keywords
- effective
- concentrations
- prevention
- combinations
- controlling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
WO 2006/072259 PCT/EG2005/000044 1 Taurine synthesis, production and utility as a medicine Technical Field: 1. Medicine Background Art: The quantitatively most important pathway for the excretion of cholesterol in mammals is the formation of bile salts (the conjugate bases of bile acids). The major bile salts are synthesized and secreted by as glycine or taurine conjugates. Disclosure of Invention: Taurine is a degradation product of cysteine. Taurine (2-aminoethyl sulphonic acid) is a component of bile. It combines with cholic acid to form taurocholic acid. Cholic acid is the metabolic fate of cholesterol. The formation of cholic acid involves a pathway involving several hydroxylations and oxidation reactions. All water soluble vitamins participate in these reactions. Taurine lowers cholesterol, and this action is potentiated by the presence of water soluble vitamins. Taurine is effective in lowering hypercholesterolaemia, hypertriglyceridaemia and all lipid associated disorders as in cholestasis or nephrotic syndrome, etc.. also it is effective in any type of familial or idiopathic or acquired lipid disorder. Taurine is cardioprotective. Taurine is also effective in gall stone dissolution. Taurine is safe, and effective in normalizing high cholesterol, low density lipoproteins, or very low density lipoproteins. Taurine is also essential for stabilizing brain cells against changes in blood osmolality, and in conversion of serotonin to endorphins. It is effective in depression, migraine, headache, Alzheimer disease, and in psychiatric and neurological diseases.
WO 2006/072259 PCT/EG2005/000044 2 The Novel Idea: To control: blood levels of lipids, lipoproteins, cholesterol, and hypercholestrolaemia associated diseases, psychiatric and neurological diseases and in gall stone dissolution, the following singly or combined are effective: a. Taurine b. Cysteine and/or acetyl cysteine, c. All water soluble vitamins. Detailed Description of the Requested Patent: a. Taurine manufactured by all known ways as sulphonation of ethyl alcohol followed by substitution reaction at C2 or recombinant DNA technology to produce 2 aminoethyl sulphonic acid or any possible way, or by the use probiotics to promote the use of intestinal bacterial flora to reclaim taurine from the previously liver formed taurocholic acid and taurochenodexoycholic acid etc.... b. Acetyl cysteine is manufactured by all known ways. c. Water soluble vitamins are manufactured by all known ways. Where: i. All " a" "b" and "c" are effective if given as "a", or "b" or "c" or as "a+b", or "a+c"; or "b+c" or, "a+ b+ c". ii. All " a" "b" and "c" are effective if given as 'a", or "b" or "c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" when provided in oral or parenteral, or topical preparations. iii. All and any composition and any and all concentrations of ''a'', or "b" or "'c"5 or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" are effective. iv. Taurine used comes in its acid form or acid salt or alkali salt or in any of its compounds, or forms.
WO 2006/072259 PCT/EG2005/000044 3 v. The "a", or "b" or 4c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling asthersclerosis and cardiac diseases. vi. The "a", or "b" or "c"' or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling all hypercholestrolaemias, hypertriglycerdaemias, and all and any lipid and lipoprotein disorders. vii. The "a", or "b" or "c" or as "a+b", or "'a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling cholestasis disorders of any aetiology. viii. The "a", or "b" or "c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling steatosis of liver and steatohepatitis disorders of any aetiology. ix. The "a", or "b" or "c" or as "a+b", or ''a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention, dissolution and controlling gall stone diseases. x. The "a", or "b" or "c"5 or as "a+b", or "a+c", or "b+c or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling all psychiatric and all neurologic diseases.
Claims (10)
1. All "a", "b" and "c" are effective if given as "a", or "b" or "c" or as "a+b", or ''a+c", or "b+c" or, "a+ b+ c".
2. All "a", "b" and "c" are effective if given as "a", or "b" or "'c"l or as "a+b" , or "a+c", or "b+c" or, "a+ b+ c" when provided in oral or parenteral, topical preparations.
3. All and any composition and any and all concentrations of "a", or "b" or "'c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" are effective.
4. Taurine used comes in its acid form or acid salt or alkali salt or in any of its compounds, forms or shapes.
5. The "a", or "b" or "'c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling astherselerosis and cardiac diseases. WO 2006/072259 PCT/EG2005/000044 5
6. The "a", or "b" or "c" or as "a+b", or ''a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling all hypercholestrolaemias, hypertriglycerdaemias, and all and any lipid and lipoprotein disorders.
7. The "a", or "b" or "c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are .effective in prevention and controlling cholestasis disorders of any aetiology.
8. The "a", or "b" or 6c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling steatosis of liver and steatohepatitis disorders of any aetiology.
9. The "a", or "b" or 4c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling gall stone diseases.
10. The "a", or "b" or "c" or as "a+b", or "a+c", or "b+c" or, "a+ b+ c" in any and all concentrations and combinations are effective in prevention and controlling all psychiatric and all neurologic diseases.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EG2005010013 | 2005-01-05 | ||
EG2005010013 | 2005-01-05 | ||
PCT/EG2005/000044 WO2006072259A2 (en) | 2005-01-05 | 2005-12-31 | Taurine synthesis, production and utility as a medicine |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2005324199A1 true AU2005324199A1 (en) | 2006-07-13 |
Family
ID=36647837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2005324199A Abandoned AU2005324199A1 (en) | 2005-01-05 | 2005-12-31 | Taurine synthesis, production and utility as a medicine |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1844006A2 (en) |
JP (1) | JP2008526789A (en) |
KR (1) | KR20070091198A (en) |
CN (1) | CN101146767A (en) |
AP (1) | AP2007004084A0 (en) |
AU (1) | AU2005324199A1 (en) |
BR (1) | BRPI0519606A2 (en) |
CA (1) | CA2593563A1 (en) |
EA (1) | EA200701434A1 (en) |
IL (1) | IL184221A0 (en) |
MA (1) | MA29238B1 (en) |
MX (1) | MX2007008196A (en) |
NO (1) | NO20074937A (en) |
TN (1) | TNSN07226A1 (en) |
WO (1) | WO2006072259A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100091219A (en) | 2007-11-30 | 2010-08-18 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products |
CN103382170B (en) * | 2012-10-25 | 2015-04-08 | 潜江永安药业股份有限公司 | Preparation method for taurine |
CN106728405A (en) * | 2016-11-15 | 2017-05-31 | 陈思文 | A kind of taurine and water soluble tea polyphenol compound and preparation method and application |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58140017A (en) * | 1981-12-22 | 1983-08-19 | Junichi Azuma | Remedy for cardiac insufficiency |
JPH08208464A (en) * | 1994-12-02 | 1996-08-13 | Taisho Pharmaceut Co Ltd | Agent for treatment and prevention of hyperlipemia |
US6184227B1 (en) * | 1995-07-21 | 2001-02-06 | Savvipharm Inc. | Salts of aminoimidazole carboxamide useful in the prevention and treatment of liver diseases |
SE9601395D0 (en) * | 1996-04-12 | 1996-04-12 | Dieter Haeussinger | New therapeutic treatment 1 |
GB9722361D0 (en) * | 1997-10-24 | 1997-12-17 | Pharma Nord Uk Ltd | Pharmaceutical formulation for treating liver disorders |
NZ527924A (en) * | 1999-01-29 | 2005-01-28 | Mars Uk Ltd | Antioxidant compositions and methods for companion animals |
WO2001026642A2 (en) * | 1999-10-08 | 2001-04-19 | Joyce Corinne Bechthold | Methods and compositions for treating neurobehavioral disorders |
CN1340502A (en) * | 2000-06-30 | 2002-03-20 | 张永春 | Process for preparing taurine zinc |
CN1268733C (en) * | 2004-07-20 | 2006-08-09 | 刘辉 | Taurine functional beer and its producing process |
-
2005
- 2005-12-31 MX MX2007008196A patent/MX2007008196A/en not_active Application Discontinuation
- 2005-12-31 CN CNA2005800460663A patent/CN101146767A/en active Pending
- 2005-12-31 WO PCT/EG2005/000044 patent/WO2006072259A2/en active Application Filing
- 2005-12-31 EP EP05818935A patent/EP1844006A2/en not_active Withdrawn
- 2005-12-31 AP AP2007004084A patent/AP2007004084A0/en unknown
- 2005-12-31 KR KR1020077016443A patent/KR20070091198A/en not_active Application Discontinuation
- 2005-12-31 BR BRPI0519606-0A patent/BRPI0519606A2/en not_active IP Right Cessation
- 2005-12-31 AU AU2005324199A patent/AU2005324199A1/en not_active Abandoned
- 2005-12-31 CA CA002593563A patent/CA2593563A1/en not_active Abandoned
- 2005-12-31 EA EA200701434A patent/EA200701434A1/en unknown
- 2005-12-31 JP JP2007549796A patent/JP2008526789A/en active Pending
-
2007
- 2007-06-14 TN TNP2007000226A patent/TNSN07226A1/en unknown
- 2007-06-26 IL IL184221A patent/IL184221A0/en unknown
- 2007-07-26 MA MA30110A patent/MA29238B1/en unknown
- 2007-09-28 NO NO20074937A patent/NO20074937A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MX2007008196A (en) | 2008-02-22 |
TNSN07226A1 (en) | 2008-11-21 |
IL184221A0 (en) | 2008-12-29 |
AP2007004084A0 (en) | 2007-08-31 |
CN101146767A (en) | 2008-03-19 |
WO2006072259A2 (en) | 2006-07-13 |
MA29238B1 (en) | 2008-02-01 |
WO2006072259A3 (en) | 2007-10-04 |
EP1844006A2 (en) | 2007-10-17 |
CA2593563A1 (en) | 2006-07-13 |
KR20070091198A (en) | 2007-09-07 |
JP2008526789A (en) | 2008-07-24 |
EA200701434A1 (en) | 2008-10-30 |
NO20074937A (en) | 2007-09-28 |
BRPI0519606A2 (en) | 2009-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |