KR20070091198A - Taurine synthesis, production and utility as a medicine - Google Patents

Abstract

The quantitatively most important pathway for the excretion of cholesterol in mammals is the formation of bile salts (the conjugate bases of bile acids). The major bile salts are synthesized and secreted by as glycine or taurine conjugates. Taurine (2 aminoethyl sulphonic acid) is naturally produced by the liver cells and central nervous system cells, it is neuroprotective and is a cholesterol lowering agent with virtually no recorded side effects.

Description

TAURINE SYNTHESIS, PRODUCTION AND UTILITY AS A MEDICINE}

medicine

The quantitatively most important route for the release of cholesterol in mammals is the formation of bile salts (covalent bases of bile acids). The major bile salts are synthesized and secreted as glycine or taurine conjugates.

Disclosure of the Invention

Taurine is a degradation product of cysteine. Taurine (2-aminoethyl sulfonic acid) is a component of bile. It combines with cholic acid to form taurocholine acid. Choline acid is the product of cholesterol metabolism. Formation of choline acid involves a pathway that involves several hydroxylation and oxidation reactions. All water soluble vitamins participate in this reaction.

Taurine lowers cholesterol levels, and this action is enhanced by the presence of water-soluble vitamins.

Taurine is effective in lowering all lipid related disorders such as hypercholesterolemia, hypertriglyceridemia and cholestasis or kidney disease, and is also effective in any type of familial or idiopathic or acquired lipid disorder. Taurine is cardioprotective.

Taurine is also effective in the treatment of gallstones.

Taurine is safe and effective at normalizing high cholesterol, low density lipoproteins, or ultra low density lipoproteins.

Taurine is also essential for stabilizing brain cells against changes in blood osmotic pressure and for converting serotonin into endorphins. It is effective in depression, migraines, headaches, Alzheimer's disease and mental and nervous system diseases.

New ideas

Controlling: Treatment of diseases related to lipids, lipoproteins, blood levels of cholesterol and hypercholesterolemia, mental and neurological diseases and gallstones, alone or in combination, are effective:

a. Taurine

b. Cysteine and / or acetyl cysteine

c. All water soluble vitamins

Detailed description of the required patent

a. Production of 2-aminoethyl sulfonic acid by substitution reaction or recombinant DNA technology at C2 after sulfonation of ethyl alcohol or by any known method or by the use of bacterial flora that is parasitic in the intestine A taurine produced by recovering taurine from taurocholine acid, taurokenodeoxycholic acid, etc. previously formed in the liver using a promoting probiotic.

b. Acetyl cysteine prepared by all known methods.

c. Water soluble vitamins prepared by all known methods.

From here:

Iii. If given as "a" or "b" or "c", or as "a + b" or "a + c" or "b + c" or "a + b + c", all "a", "b "And" c "are effective.

Ii. When provided in oral or parenteral or topical formulations, as "a" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + If given as "c", all "a" or "b" and "c" are effective.

Iii. all and any composition and any and all concentrations of “a” or “b” or “c”, or “a + b” or “a + c” or “b + c” or “a + b + c” Is effective.

Iii. The taurine used is represented in its acid form or in acid or alkali salts or in any compound or form thereof.

Iii. Any and all concentrations and combinations of "a" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + c" means atherosclerosis and Effective for the prevention and control of heart disease.

Iii. Any and all concentrations and combinations of “a” or “b” or “c”, or “a + b” or “a + c” or “b + c” or “a + b + c” are all high cholesterol It is effective in the prevention and control of hypertension, hypertriglyceridemia and all and any lipid and lipoprotein disorders.

Iii. Any and all concentrations and combinations of "a" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + c" is any etiology It is effective in the prevention and control of cholestasis of bile.

Iii. Any and all concentrations and combinations of “a” or “b” or “c”, or “a + b” or “a + c” or “b + c” or “a + b + c” is a fatty steatosis and It is effective in the prevention and control of hepatitis disorders of any etiology.

Iii. Any and all concentrations and combinations of "a" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + c" may be used for gallstone disease Effective for prevention, treatment and control.

Iii. Any and all concentrations and combinations of “a” or “b” or “c”, or “a + b” or “a + c” or “b + c” or “a + b + c” are all mental disorders And effective in the prevention and control of all neurological diseases.

Claims (10)

If given as "a" or "b" or "c", or as "a + b" or "a + c" or "b + c" or "a + b + c", all "a", "b "And" c "are effective. Provided that a is a bacterial flora that is parasitic to the intestine by any known method or by any known method of producing 2-aminoethyl sulfonic acid by substitution reaction or recombinant DNA technology at C2 after sulfonation of ethyl alcohol. Taurine prepared by recovering taurine from taurocholinic acid, taurokenodeoxycholic acid, etc. previously formed in the liver using a probiotic that promotes the use of b is acetyl cysteine prepared by all known methods, c is a water soluble vitamin prepared by all known methods. When provided in oral or parenteral or topical formulations, as "a" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + If given as "c", all "a" or "b" and "c" are effective. Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "b + c" or "a + b + c, in which all and any compositions and any and all concentrations are effective ". Provided that a, b, and c are as defined in claim 1. Taurine used in the acid form or acid salt or alkali salt of taurine or in any compound or form or form thereof. Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "b + c" in any and all concentrations and combinations effective for the prevention and control of atherosclerosis and heart disease "a + b + c". Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or any and all concentrations and combinations effective for the prevention and control of all hypercholesterolemia, hypertriglyceridemia and all and any lipid and lipoprotein disorders "a + c" or "b + c" or "a + b + c". Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "b + c" in any and all concentrations and combinations effective for the prevention and control of the cholestasis of any etiology Or "a + b + c". Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "of any and all concentrations and combinations effective for the prevention and control of hepatic steatosis and hepatic hepatitis disorder of any etiology b + c "or" a + b + c ". Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "b + c" or "of any and all concentrations and combinations effective for the prevention, treatment and control of gallstone disease a + b + c ". Provided that a, b, and c are as defined in claim 1. "A" or "b" or "c", or "a + b" or "a + c" or "b + c, in any and all concentrations and combinations effective for the prevention and control of all mental and all neurological diseases "Or" a + b + c ". Provided that a, b, and c are as defined in claim 1.