AU2005306429B2 - Microneedle array applicator and retainer - Google Patents
Microneedle array applicator and retainer Download PDFInfo
- Publication number
- AU2005306429B2 AU2005306429B2 AU2005306429A AU2005306429A AU2005306429B2 AU 2005306429 B2 AU2005306429 B2 AU 2005306429B2 AU 2005306429 A AU2005306429 A AU 2005306429A AU 2005306429 A AU2005306429 A AU 2005306429A AU 2005306429 B2 AU2005306429 B2 AU 2005306429B2
- Authority
- AU
- Australia
- Prior art keywords
- microneedle
- elastic band
- band
- microneedle device
- skin surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 13
- 239000003814 drug Substances 0.000 abstract description 12
- 229940079593 drug Drugs 0.000 abstract description 8
- 230000035515 penetration Effects 0.000 abstract description 3
- 210000003491 skin Anatomy 0.000 description 73
- 238000005520 cutting process Methods 0.000 description 18
- 230000037317 transdermal delivery Effects 0.000 description 8
- 229920001971 elastomer Polymers 0.000 description 7
- 239000005060 rubber Substances 0.000 description 6
- 238000003780 insertion Methods 0.000 description 5
- 230000037431 insertion Effects 0.000 description 5
- 239000002831 pharmacologic agent Substances 0.000 description 5
- 210000000434 stratum corneum Anatomy 0.000 description 5
- 238000003491 array Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 150000002605 large molecules Chemical class 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 238000002493 microarray Methods 0.000 description 2
- 210000000944 nerve tissue Anatomy 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 229940122361 Bisphosphonate Drugs 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 229940021995 DNA vaccine Drugs 0.000 description 1
- 229920002943 EPDM rubber Polymers 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 229920000459 Nitrile rubber Polymers 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- DCSBSVSZJRSITC-UHFFFAOYSA-M alendronate sodium trihydrate Chemical compound O.O.O.[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O DCSBSVSZJRSITC-UHFFFAOYSA-M 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 150000004663 bisphosphonates Chemical class 0.000 description 1
- 229960004755 ceftriaxone Drugs 0.000 description 1
- VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 210000005224 forefinger Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- -1 heparin Chemical class 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 150000003839 salts Chemical group 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229920006132 styrene block copolymer Polymers 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/02—Holding devices, e.g. on the body
- A61M2025/0253—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/02—Holding devices, e.g. on the body
- A61M2025/0253—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives
- A61M2025/026—Holding devices, e.g. on the body where the catheter is attached by straps, bands or the like secured by adhesives where the straps are releasably secured, e.g. by hook and loop-type fastening devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Micromachines (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62914304P | 2004-11-18 | 2004-11-18 | |
| US60/629,143 | 2004-11-18 | ||
| PCT/US2005/041870 WO2006055802A1 (en) | 2004-11-18 | 2005-11-18 | Microneedle array applicator and retainer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2005306429A1 AU2005306429A1 (en) | 2006-05-26 |
| AU2005306429B2 true AU2005306429B2 (en) | 2011-04-14 |
Family
ID=35892434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005306429A Ceased AU2005306429B2 (en) | 2004-11-18 | 2005-11-18 | Microneedle array applicator and retainer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9174035B2 (enExample) |
| EP (1) | EP1838383B1 (enExample) |
| JP (1) | JP4927752B2 (enExample) |
| CN (1) | CN101060882B (enExample) |
| AT (1) | ATE504328T1 (enExample) |
| AU (1) | AU2005306429B2 (enExample) |
| CA (1) | CA2587386C (enExample) |
| DE (1) | DE602005027397D1 (enExample) |
| WO (1) | WO2006055802A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1871459B1 (en) | 2005-04-07 | 2019-06-19 | 3M Innovative Properties Company | System for tool feedback sensing |
| WO2006138719A2 (en) | 2005-06-17 | 2006-12-28 | Georgia Tech Research Corporation | Coated microstructures and method of manufacture thereof |
| US9119945B2 (en) * | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
| GB2448493B (en) | 2007-04-16 | 2009-10-14 | Dewan Fazlul Hoque Chowdhury | Microneedle transdermal delivery device |
| AU2008241470B2 (en) * | 2007-04-16 | 2013-11-07 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
| WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
| WO2010022326A2 (en) * | 2008-08-22 | 2010-02-25 | Us Worldmeds Llc | Transdermal delivery of apomorphine using microneedles |
| US20110213335A1 (en) | 2008-11-18 | 2011-09-01 | Burton Scott A | Hollow microneedle array and method |
| US20110009782A1 (en) * | 2009-07-07 | 2011-01-13 | Naya Touch, Inc. | Dermal roller with therapeutic microstructures |
| WO2011140274A2 (en) | 2010-05-04 | 2011-11-10 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
| AU2011248166B2 (en) * | 2010-05-04 | 2015-12-17 | Corium Pharma Solutions, Inc. | Applicators for microneedles |
| WO2012048285A1 (en) * | 2010-10-08 | 2012-04-12 | Lanco Biosciences, Inc. | Delivery of bisphosphonates by microinjection systems |
| WO2012075339A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of heparins by microinjection systems |
| WO2012075209A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of triptans by microinjection systems |
| WO2012075375A1 (en) * | 2010-12-02 | 2012-06-07 | Lanco Biosciences, Inc. | Delivery of parathyroid hormones by microinjection systems |
| CN102805896A (zh) * | 2011-05-30 | 2012-12-05 | 惠觅宙 | 经皮给药方法、制剂和系统 |
| CN103889474B (zh) | 2011-08-15 | 2016-09-07 | Meko激光材料加工公司 | 镁合金和包含该镁合金的可吸收的支架 |
| CA2847711C (en) * | 2011-09-07 | 2019-08-20 | 3M Innovative Properties Company | Delivery system for hollow microneedle arrays |
| JP5921557B2 (ja) * | 2011-09-16 | 2016-05-24 | 久光製薬株式会社 | アプリケータ |
| US9789299B2 (en) | 2012-11-16 | 2017-10-17 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| KR102265808B1 (ko) | 2012-12-21 | 2021-06-16 | 코리움, 인크. | 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법 |
| EP2938390A1 (en) | 2012-12-27 | 2015-11-04 | 3M Innovative Properties Company | Article with hollow microneedles and method of making |
| EP2968887B1 (en) | 2013-03-12 | 2022-05-04 | Corium, Inc. | Microprojection applicators |
| EP4194028A1 (en) | 2013-03-15 | 2023-06-14 | Corium Pharma Solutions, Inc. | Multiple impact microprojection applicators |
| CN105246458B (zh) | 2013-03-15 | 2020-09-15 | 考里安公司 | 用于治疗剂递送的微阵列及其使用方法 |
| JP2016512754A (ja) | 2013-03-15 | 2016-05-09 | コリウム インターナショナル， インコーポレイテッド | 治療剤の送達のためのマイクロアレイ、使用方法および製造方法 |
| EP2968116A1 (en) | 2013-03-15 | 2016-01-20 | Corium International, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
| EP3047871B1 (en) * | 2013-09-18 | 2018-05-02 | Cosmed Pharmaceutical Co., Ltd. | Microneedle patch application device and patch holder |
| EP3188714A1 (en) | 2014-09-04 | 2017-07-12 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
| KR101688273B1 (ko) * | 2014-10-17 | 2016-12-21 | (의료)길의료재단 | 조임 수단을 포함하는 마이크로 니들 조립체 |
| ES2945899T3 (es) * | 2015-04-17 | 2023-07-10 | Georgia Tech Res Inst | Dispositivos de administración de fármacos que tienen microagujas separables |
| WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| WO2017151806A1 (en) | 2016-03-01 | 2017-09-08 | Kitotech Medical, Inc. | Microstructure-based systems, apparatus, and methods for wound closure |
| KR20190088073A (ko) | 2016-12-16 | 2019-07-25 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 유체 전달 장치용 부착 밴드 및 그 이용 방법 |
| WO2019075275A1 (en) | 2017-10-11 | 2019-04-18 | Georgia Tech Research Corporation | SEPARABLE MICROARRAY MATRICES FOR PROLONGED MEDICATION RELEASE |
| KR102271338B1 (ko) * | 2018-03-27 | 2021-06-29 | 연세대학교 산학협력단 | 마이크로 니들 어플리케이터 |
| DE102019200561A1 (de) * | 2019-01-17 | 2020-07-23 | Lts Lohmann Therapie-Systeme Ag | Träger |
| KR102368260B1 (ko) * | 2020-01-09 | 2022-03-02 | 연세대학교 산학협력단 | 마이크로니들 어플리케이터 |
| US11986613B2 (en) | 2020-02-19 | 2024-05-21 | Kitotech Medical, Inc. | Microstructure systems and methods for pain treatment |
| US11389632B2 (en) | 2020-12-21 | 2022-07-19 | Mediccene Inc. | Intradermal drug delivery device |
| US12048543B2 (en) | 2021-11-08 | 2024-07-30 | Satio, Inc. | Dermal patch for collecting a physiological sample with removable vial |
| US12214346B2 (en) | 2021-10-13 | 2025-02-04 | Satio, Inc. | Dermal patch with a diagnostic test strip |
| US12178979B2 (en) | 2021-10-13 | 2024-12-31 | Satio, Inc. | Dermal patch for delivering a pharmaceutical |
| US12029562B2 (en) | 2021-04-14 | 2024-07-09 | Satio, Inc. | Dermal patch system |
| US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12053284B2 (en) | 2021-11-08 | 2024-08-06 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
| CN113499537A (zh) * | 2021-09-03 | 2021-10-15 | 河南佳普医药科技有限公司 | 一种微针透皮给药装置 |
| CN120899241A (zh) | 2021-09-28 | 2025-11-07 | 比奥林公司 | 用于基于微针阵列的持续分析物监测设备的微针封壳和施加器装置 |
| USD1033641S1 (en) | 2021-12-17 | 2024-07-02 | Biolinq Incorporated | Microneedle array sensor applicator device |
| US11957346B2 (en) | 2022-02-18 | 2024-04-16 | Kitotech Medical, Inc. | Force modulating deep skin staples and instruments |
| USD1057153S1 (en) | 2022-04-29 | 2025-01-07 | Biolinq Incorporated | Microneedle array sensor applicator device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6050988A (en) * | 1997-12-11 | 2000-04-18 | Alza Corporation | Device for enhancing transdermal agent flux |
| US6219574B1 (en) * | 1996-06-18 | 2001-04-17 | Alza Corporation | Device and method for enchancing transdermal sampling |
| US20030187395A1 (en) * | 2002-04-02 | 2003-10-02 | Gabel Jonathan B. | Intradermal delivery device |
Family Cites Families (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE25637E (en) | 1964-09-08 | Means for vaccinating | ||
| US3123212A (en) | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
| US3072122A (en) | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
| US3034507A (en) | 1960-05-10 | 1962-05-15 | American Cyanamid Co | Intracutaneous injection device |
| US3136314A (en) | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
| US3246647A (en) | 1962-07-23 | 1966-04-19 | American Cyanamid Co | Disposable intracutaneous injector |
| US3221740A (en) | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
| GB1080986A (en) | 1964-09-02 | 1967-08-31 | Allen And Hanburys Surgical En | Multiple puncture apparatus |
| US3322121A (en) | 1965-11-26 | 1967-05-30 | Oscar H Banker | Skin-puncturing unit with a collapsible protective cover |
| US3510933A (en) | 1967-05-26 | 1970-05-12 | American Cyanamid Co | Apparatus and method for continuously forming intracutaneous injectors |
| US3466131A (en) | 1967-09-07 | 1969-09-09 | Becton Dickinson Co | Dispensing applicator package |
| US3512520A (en) | 1967-11-01 | 1970-05-19 | Michael N Cowan | Antigenic test applicator |
| US3596660A (en) | 1969-05-12 | 1971-08-03 | Illinois Tool Works | Injection device |
| US3675766A (en) | 1970-02-04 | 1972-07-11 | Sol Roy Rosenthal | Multiple puncture injector device |
| US3688764A (en) | 1970-08-20 | 1972-09-05 | Bard Hamilton Co Inc | Intracutaneous injection system |
| US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| US3678150A (en) | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
| DE2250293A1 (de) | 1972-10-13 | 1974-04-25 | Bayern Freistaat | Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff |
| US3908356A (en) * | 1974-11-04 | 1975-09-30 | William J Williams | Watch case and band |
| OA05448A (fr) | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
| US4304241A (en) | 1978-09-05 | 1981-12-08 | Aller-Screen, Inc. | Skin testing device |
| US4237906A (en) | 1978-12-06 | 1980-12-09 | Havstad Harold R | Antigen injection assembly |
| GB2064329B (en) | 1979-11-01 | 1983-06-22 | Matburn Holdings Ltd | Multiple puncture apparatus |
| FR2474856A1 (fr) | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
| US4360016A (en) | 1980-07-01 | 1982-11-23 | Transidyne General Corp. | Blood collecting device |
| US4503856A (en) | 1981-06-29 | 1985-03-12 | Sherwood Medical Company | Lancet injector |
| US4517978A (en) | 1983-01-13 | 1985-05-21 | Levin Paul D | Blood sampling instrument |
| US4474751A (en) | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
| US4627445A (en) | 1985-04-08 | 1986-12-09 | Garid, Inc. | Glucose medical monitoring system |
| GB8710470D0 (en) | 1987-05-01 | 1987-06-03 | Mumford Ltd Owen | Blood sampling devices |
| US4850973A (en) | 1987-10-16 | 1989-07-25 | Pavel Jordon & Associates | Plastic device for injection and obtaining blood samples |
| US5192535A (en) | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| GB2221394B (en) | 1988-08-05 | 1992-03-04 | Eilert Eilertsen | An injection device |
| US4924879A (en) | 1988-10-07 | 1990-05-15 | Brien Walter J O | Blood lancet device |
| US4920977A (en) | 1988-10-25 | 1990-05-01 | Becton, Dickinson And Company | Blood collection assembly with lancet and microcollection tube |
| CA2016900A1 (en) | 1989-07-06 | 1991-01-06 | Ronald J. Filipski | Tines structure in clinical applicator |
| EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
| US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
| US5402798A (en) | 1991-07-18 | 1995-04-04 | Swierczek; Remi | Disposable skin perforator and blood testing device |
| DE4212315A1 (de) | 1992-04-13 | 1993-10-14 | Boehringer Mannheim Gmbh | Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke |
| US5340572A (en) | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
| JP2630197B2 (ja) | 1993-04-28 | 1997-07-16 | 株式会社ニッショー | 血液吸出器具 |
| CA2149943C (en) | 1994-05-23 | 1999-07-13 | Kwang Kyun Jang | Skin perforating device for transdermal medication |
| US5487726A (en) | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
| AU3758595A (en) | 1994-09-30 | 1996-04-26 | Rutgers, The State University | Direct introduction of foreign materials into cells |
| WO1996037155A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical device and method for enhancing delivery of compounds through the skin |
| WO1996037256A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
| DE19525607A1 (de) | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
| US5639000A (en) * | 1995-08-21 | 1997-06-17 | Mcdaniel; V. Robin | Watch band assembly |
| WO1998011937A1 (en) | 1996-09-17 | 1998-03-26 | Deka Products Limited Partnership | System for delivery of drugs by transport |
| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| KR100557261B1 (ko) | 1997-12-11 | 2006-03-07 | 알자 코포레이션 | 경피성 작용제 유동률을 증진시키기 위한 장치 |
| CA2575064C (en) | 1997-12-31 | 2010-02-02 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
| US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| JP3382853B2 (ja) * | 1998-04-09 | 2003-03-04 | 松下電器産業株式会社 | 体液検査装置 |
| AU767122B2 (en) | 1998-06-10 | 2003-10-30 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
| US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| GB9817662D0 (en) | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
| US6532386B2 (en) | 1998-08-31 | 2003-03-11 | Johnson & Johnson Consumer Companies, Inc. | Electrotransort device comprising blades |
| US6713291B2 (en) | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
| EP1163024B1 (en) | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Delivery of macromolecules into cells |
| TW480759B (en) | 1999-03-18 | 2002-03-21 | Seiko Epson Corp | Electronic machine, charged electronic machine and control method of electronic machine |
| US6743211B1 (en) | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6611707B1 (en) * | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
| US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
| US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
| US6623457B1 (en) | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
| US20020095134A1 (en) | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| CN101238998A (zh) | 1999-11-15 | 2008-08-13 | 维尔克工业有限公司 | 皮肤附着件 |
| HK1048773B (en) | 1999-12-10 | 2005-10-14 | Alza Corporation | Skin treatment apparatus for sustained transdermal drug delivery |
| DK1239916T3 (da) | 1999-12-10 | 2006-04-03 | Alza Corp | Indretning og fremgangsmåde til at forbedre perforering af hud med mikrofremspring |
| US6881538B1 (en) | 2000-03-05 | 2005-04-19 | 3M Innovative Properties Company | Array comprising diamond-like glass film |
| US6595947B1 (en) | 2000-05-22 | 2003-07-22 | Becton, Dickinson And Company | Topical delivery of vaccines |
| US7473244B2 (en) | 2000-06-02 | 2009-01-06 | The University Of Utah Research Foundation | Active needle devices with integrated functionality |
| US6537242B1 (en) * | 2000-06-06 | 2003-03-25 | Becton, Dickinson And Company | Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance |
| US6589202B1 (en) | 2000-06-29 | 2003-07-08 | Becton Dickinson And Company | Method and apparatus for transdermally sampling or administering a substance to a patient |
| US6440096B1 (en) | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
| US6656147B1 (en) * | 2000-07-17 | 2003-12-02 | Becton, Dickinson And Company | Method and delivery device for the transdermal administration of a substance |
| GB0017999D0 (en) | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| KR20030068137A (ko) | 2000-10-13 | 2003-08-19 | 알자 코포레이션 | 충격 어플리케이터용 미세 돌기 부재 리테이너 |
| HUP0303583A2 (en) * | 2000-10-13 | 2004-01-28 | Alza Corp | Microblade array impact applicator |
| RU2275871C2 (ru) | 2000-10-13 | 2006-05-10 | Алза Корпорейшн | Устройство и способ для прокалывания кожи микровыступами |
| US7131987B2 (en) | 2000-10-16 | 2006-11-07 | Corium International, Inc. | Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation |
| WO2002045771A2 (en) | 2000-11-09 | 2002-06-13 | Biovalve Technologies, Inc. | Microneedle adapter |
| ES2717656T3 (es) | 2000-11-30 | 2019-06-24 | Valeritas Inc | Dispositivo con microsonda amovible sustancialmente libre sobre el alojamiento |
| US9302903B2 (en) | 2000-12-14 | 2016-04-05 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
| US6591124B2 (en) | 2001-05-11 | 2003-07-08 | The Procter & Gamble Company | Portable interstitial fluid monitoring system |
| WO2002100476A2 (en) | 2001-06-08 | 2002-12-19 | Becton, Dickinson And Company | Device for manipulating a needle or abrader array |
| WO2003002069A2 (en) | 2001-06-29 | 2003-01-09 | Becton, Dickinson And Company | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
| US6881203B2 (en) | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
| ES2393282T3 (es) | 2001-09-12 | 2012-12-20 | Becton, Dickinson And Company | Dispositivo de pluma basado en microaguja para la administración de fármacos |
| CA2499838C (en) | 2001-09-21 | 2012-12-18 | Biovalve Technologies, Inc. | Gas pressure actuated microneedle arrays, and systems and methods relating to same |
| US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
| US6908453B2 (en) | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
| JP2005520617A (ja) * | 2002-03-20 | 2005-07-14 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 生検針 |
| CA2492867C (en) | 2002-07-19 | 2011-07-05 | 3M Innovative Properties Company | Microneedle devices and microneedle delivery apparatus |
| BRPI0312846B8 (pt) | 2002-07-22 | 2021-06-22 | Becton Dickinson Co | dispositivo de infusão semelhante a emplastro |
| US7166086B2 (en) | 2002-08-29 | 2007-01-23 | Becton, Dickinson And Company | Substance delivery via a rotating microabrading surface |
| AU2004251699A1 (en) | 2003-06-04 | 2005-01-06 | Georgia Tech Research Corporation | Drilling microneedle device |
| CA2530954A1 (en) | 2003-07-02 | 2005-01-13 | Alza Corporation | Microprojection array immunization patch and method |
| EP1654018A4 (en) | 2003-08-12 | 2010-11-17 | Becton Dickinson Co | PLASTER-INFUSION DEVICE |
| US8353861B2 (en) | 2003-09-18 | 2013-01-15 | Texmac, Inc. | Applicator for applying functional substances into human skin |
| WO2005042054A2 (en) | 2003-10-24 | 2005-05-12 | Alza Corporation | Pretreatment method and system for enhancing transdermal drug delivery |
| BRPI0415629A (pt) | 2003-10-31 | 2006-12-12 | Alza Corp | aplicador auto-atuador para conjunto de microprojeções |
| AU2004292953A1 (en) | 2003-11-21 | 2005-06-09 | Alza Corporation | Ultrasound assisted transdermal vaccine delivery method and system |
| JP2007512052A (ja) | 2003-11-28 | 2007-05-17 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | 迅速な経皮投与系および方法 |
| CA2552385C (en) | 2003-12-29 | 2013-07-23 | 3M Innovative Properties Company | Medical devices and kits including same |
| US20070191761A1 (en) | 2004-02-23 | 2007-08-16 | 3M Innovative Properties Company | Method of molding for microneedle arrays |
-
2005
- 2005-11-18 JP JP2007543285A patent/JP4927752B2/ja not_active Expired - Fee Related
- 2005-11-18 DE DE602005027397T patent/DE602005027397D1/de not_active Expired - Lifetime
- 2005-11-18 AU AU2005306429A patent/AU2005306429B2/en not_active Ceased
- 2005-11-18 CA CA2587386A patent/CA2587386C/en not_active Expired - Fee Related
- 2005-11-18 EP EP05851821A patent/EP1838383B1/en not_active Expired - Lifetime
- 2005-11-18 AT AT05851821T patent/ATE504328T1/de not_active IP Right Cessation
- 2005-11-18 WO PCT/US2005/041870 patent/WO2006055802A1/en not_active Ceased
- 2005-11-18 CN CN200580039526XA patent/CN101060882B/zh not_active Expired - Fee Related
- 2005-11-18 US US11/718,461 patent/US9174035B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6219574B1 (en) * | 1996-06-18 | 2001-04-17 | Alza Corporation | Device and method for enchancing transdermal sampling |
| US6050988A (en) * | 1997-12-11 | 2000-04-18 | Alza Corporation | Device for enhancing transdermal agent flux |
| US20030187395A1 (en) * | 2002-04-02 | 2003-10-02 | Gabel Jonathan B. | Intradermal delivery device |
| WO2003084597A1 (en) * | 2002-04-02 | 2003-10-16 | Becton, Dickinson And Company | Device for intradermal medicament delivery |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080009825A1 (en) | 2008-01-10 |
| EP1838383B1 (en) | 2011-04-06 |
| EP1838383A1 (en) | 2007-10-03 |
| CA2587386A1 (en) | 2006-05-26 |
| ATE504328T1 (de) | 2011-04-15 |
| DE602005027397D1 (de) | 2011-05-19 |
| CN101060882B (zh) | 2010-06-16 |
| AU2005306429A1 (en) | 2006-05-26 |
| US9174035B2 (en) | 2015-11-03 |
| JP2008520371A (ja) | 2008-06-19 |
| JP4927752B2 (ja) | 2012-05-09 |
| CN101060882A (zh) | 2007-10-24 |
| CA2587386C (en) | 2013-01-15 |
| WO2006055802A1 (en) | 2006-05-26 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |