AU2004215658B2 - Novel diazabicyclic aryl derivatives - Google Patents

Novel diazabicyclic aryl derivatives Download PDF

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Publication number
AU2004215658B2
AU2004215658B2 AU2004215658A AU2004215658A AU2004215658B2 AU 2004215658 B2 AU2004215658 B2 AU 2004215658B2 AU 2004215658 A AU2004215658 A AU 2004215658A AU 2004215658 A AU2004215658 A AU 2004215658A AU 2004215658 B2 AU2004215658 B2 AU 2004215658B2
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Australia
Prior art keywords
phenyl
diaza
bicyclo
furan
methanone
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Ceased
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AU2004215658A
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AU2004215658A1 (en
Inventor
Philip K. Ahring
Tino Dyhring Jorgensen
Elsebet Ostergaard Nielsen
Gunnar M. Olsen
Dan Peters
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
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  • Chemical Kinetics & Catalysis (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Pregnancy & Childbirth (AREA)
AU2004215658A 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives Ceased AU2004215658B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US44987103P 2003-02-27 2003-02-27
DKPA200300310 2003-02-27
US60/449,871 2003-02-27
DKPA200300310 2003-02-27
DKPA200300940 2003-06-24
DKPA200300940 2003-06-24
US48202203P 2003-06-25 2003-06-25
US60/482,022 2003-06-25
PCT/EP2004/050079 WO2004076453A1 (en) 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives

Publications (2)

Publication Number Publication Date
AU2004215658A1 AU2004215658A1 (en) 2004-09-10
AU2004215658B2 true AU2004215658B2 (en) 2010-06-24

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AU2004215658A Ceased AU2004215658B2 (en) 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives

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US (2) US7678788B2 (https=)
EP (1) EP1599476B1 (https=)
JP (1) JP2006519208A (https=)
AT (1) ATE445618T1 (https=)
AU (1) AU2004215658B2 (https=)
BR (1) BRPI0407216A (https=)
CA (1) CA2518675A1 (https=)
DE (1) DE602004023586D1 (https=)
MX (1) MXPA05006861A (https=)
NZ (1) NZ540998A (https=)
WO (1) WO2004076453A1 (https=)

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SE0202465D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
SE0202430D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
WO2004083388A2 (en) 2003-03-14 2004-09-30 Bristol-Myers Squibb Company Polynucleotide encoding a novel human g-protein coupled receptor variant of hm74, hgprbmy74
TW200529860A (en) * 2003-12-22 2005-09-16 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
EP1713810B1 (en) * 2004-02-04 2010-12-29 NeuroSearch A/S Diazabicyclic aryl derivatives as nicotinic acetylcholine receptor ligands
DE602005015682D1 (de) 2004-02-04 2009-09-10 Neurosearch As Dimere azacyclische verbindungen und deren verwendung
JP2007538011A (ja) 2004-05-07 2007-12-27 メモリー・ファーマシューティカルズ・コーポレイション １ｈ−インダゾール、ベンゾチアゾール、１，２−ベンゾイソキサゾール、１，２−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用
JP2007538046A (ja) 2004-05-19 2007-12-27 ノイロサーチ アクティーゼルスカブ 新規なアザビシクロアリール誘導体
TWI405763B (zh) 2006-11-02 2013-08-21 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
GB0723814D0 (en) * 2007-12-05 2008-01-16 Glaxo Group Ltd Compounds
DE102008015032A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte Pyrazolamide und ihre Verwendung
DE102008015033A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062863A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062878A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte Furancarboxamide und ihre Verwendung
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof
JP7551629B2 (ja) 2019-02-05 2024-09-17 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物
JP7603594B2 (ja) 2019-02-06 2024-12-20 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物

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AU2003248592A1 (en) * 2002-08-14 2004-03-03 Astrazeneca Ab Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists

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FR2791678B1 (fr) 1999-03-30 2001-05-04 Synthelabo Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
EP1177196B1 (en) * 1999-05-04 2004-03-10 Neurosearch A/S Heteroaryl diazabicycloalkanes, their preparation and use
FR2804430B1 (fr) 2000-01-28 2002-03-22 Sanofi Synthelabo Derives de 4-heteroaryl-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
US20020086871A1 (en) * 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders
DE60216830T2 (de) * 2001-02-06 2007-06-14 Pfizer Products Inc., Groton Pharmazeutische Zusammensetzungen zur Behandlung von Störungen des ZNS oder anderen Erkrankungen
FR2832713B1 (fr) 2001-11-23 2004-02-13 Sanofi Synthelabo Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2832712B1 (fr) * 2001-11-23 2004-02-13 Sanofi Synthelabo Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique
WO2004004396A1 (en) 2002-06-26 2004-01-08 Nokia Corporation Method and network element for optimisation of radio resource utilisation in a radio access network
SE0202465D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
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CA2518675A1 (en) 2004-09-10
BRPI0407216A (pt) 2006-01-24
NZ540998A (en) 2008-06-30
DE602004023586D1 (de) 2009-11-26
AU2004215658A1 (en) 2004-09-10
EP1599476B1 (en) 2009-10-14
US20100130483A1 (en) 2010-05-27
ATE445618T1 (de) 2009-10-15
WO2004076453A1 (en) 2004-09-10
EP1599476A1 (en) 2005-11-30
MXPA05006861A (es) 2005-12-12
US20060148789A1 (en) 2006-07-06
JP2006519208A (ja) 2006-08-24
US7678788B2 (en) 2010-03-16

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