AU2003282247A1 - Anti-activated ras antibodies - Google Patents

Anti-activated ras antibodies Download PDF

Info

Publication number
AU2003282247A1
AU2003282247A1 AU2003282247A AU2003282247A AU2003282247A1 AU 2003282247 A1 AU2003282247 A1 AU 2003282247A1 AU 2003282247 A AU2003282247 A AU 2003282247A AU 2003282247 A AU2003282247 A AU 2003282247A AU 2003282247 A1 AU2003282247 A1 AU 2003282247A1
Authority
AU
Australia
Prior art keywords
seq
antibody
ras
scfv
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003282247A
Other languages
English (en)
Inventor
Terence Howard Rabbitts
Tomoyuki Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0226727.6A external-priority patent/GB0226727D0/en
Priority claimed from GB0226728A external-priority patent/GB0226728D0/en
Priority claimed from GB0226731A external-priority patent/GB0226731D0/en
Priority claimed from GBGB0226729.2A external-priority patent/GB0226729D0/en
Priority claimed from GB0226723A external-priority patent/GB0226723D0/en
Priority claimed from GB0316680A external-priority patent/GB0316680D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of AU2003282247A1 publication Critical patent/AU2003282247A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003282247A 2002-11-15 2003-11-14 Anti-activated ras antibodies Abandoned AU2003282247A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GBGB0226727.6A GB0226727D0 (en) 2002-11-15 2002-11-15 Intrabodies
GB0226728A GB0226728D0 (en) 2002-11-15 2002-11-15 Anti-activated RAS antibodies
GB0226731A GB0226731D0 (en) 2002-11-15 2002-11-15 Method for generating immunoglobulin genes
GB0226728.4 2002-11-15
GBGB0226729.2A GB0226729D0 (en) 2002-11-15 2002-11-15 Intracellular antibodies
GB0226729.2 2002-11-15
GB0226723.5 2002-11-15
GB0226731.8 2002-11-15
GB0226727.6 2002-11-15
GB0226723A GB0226723D0 (en) 2002-11-15 2002-11-15 Antibodies for in vitro use
GB0316680A GB0316680D0 (en) 2003-07-16 2003-07-16 Anti-activated RAS antibodies
GB0316680.8 2003-07-16
PCT/GB2003/004953 WO2004046188A2 (en) 2002-11-15 2003-11-14 Anti-activated ras antibodies

Publications (1)

Publication Number Publication Date
AU2003282247A1 true AU2003282247A1 (en) 2004-06-15

Family

ID=32330172

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003282247A Abandoned AU2003282247A1 (en) 2002-11-15 2003-11-14 Anti-activated ras antibodies

Country Status (6)

Country Link
US (1) US20050288492A1 (https=)
EP (1) EP1565495A2 (https=)
JP (1) JP2006521088A (https=)
AU (1) AU2003282247A1 (https=)
CA (1) CA2506128A1 (https=)
WO (1) WO2004046188A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5171611B2 (ja) 2005-03-25 2013-03-27 ナショナル リサーチ カウンシル オブ カナダ 可溶性ポリペプチドの単離方法
EP1867661A1 (en) * 2006-06-12 2007-12-19 Diatos Compositions and methods for delivering anti-activated ras antibodies into cells
EP2254366B1 (en) 2008-03-12 2019-02-27 Panasonic Intellectual Property Corporation of America Radio communication device, radio communication system, and radio communication method
WO2010119249A1 (en) * 2009-04-14 2010-10-21 Trojan Technologies Ltd. Therapeutic antennapedia-antibody molecules and methods of use thereof
GB201103631D0 (en) * 2011-03-03 2011-04-13 Univ Leeds Identification of candidate therapeutics
RS61778B1 (sr) 2013-05-06 2021-06-30 Scholar Rock Inc Kompozicije i postupci za modulaciju faktora rasta
WO2016013871A1 (ko) * 2014-07-22 2016-01-28 아주대학교산학협력단 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용
KR101602870B1 (ko) 2014-07-22 2016-03-21 아주대학교산학협력단 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용
KR101602876B1 (ko) * 2014-07-22 2016-03-11 아주대학교산학협력단 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용
US9879087B2 (en) 2014-11-12 2018-01-30 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
FI3218005T3 (fi) 2014-11-12 2023-03-31 Seagen Inc Glykaanin kanssa vuorovaikutteisia yhdisteitä ja käyttömenetelmiä
CA3002097A1 (en) 2015-11-12 2017-05-18 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
MX2018014554A (es) 2016-05-27 2019-09-09 Orum Therapeutics Inc Anticuerpo penetrante de citosol y uso del mismo.
WO2018094143A1 (en) 2016-11-17 2018-05-24 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
WO2018160909A1 (en) 2017-03-03 2018-09-07 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
EP3652196A4 (en) 2017-07-10 2021-08-18 Brown, Kathlynn, C. MOLECULAR GUIDANCE SYSTEMPEPTIDES AND USES THEREOF
JP2020527556A (ja) 2017-07-10 2020-09-10 エスアールアイ インターナショナルＳＲＩ Ｉｎｔｅｒｎａｔｉｏｎａｌ がん治療用ペプチドサポリン複合体
US10787487B2 (en) 2018-06-21 2020-09-29 Orum Therapeutics Inc. Cell/tissue-specific cell-penetrating antibodies
GB202006974D0 (en) * 2020-05-12 2020-06-24 Univ Oxford Innovation Ltd Chimaeric proteins and therapeutic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003077945A1 (en) * 2002-03-14 2003-09-25 Medical Research Council Intracellular antibodies

Also Published As

Publication number Publication date
WO2004046188A2 (en) 2004-06-03
US20050288492A1 (en) 2005-12-29
WO2004046188A3 (en) 2004-09-16
EP1565495A2 (en) 2005-08-24
CA2506128A1 (en) 2004-06-03
JP2006521088A (ja) 2006-09-21

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period