AU2003259208A1 - Conjugated lysine copolymers for drug delivery and imaging - Google Patents

Conjugated lysine copolymers for drug delivery and imaging

Info

Publication number
AU2003259208A1
AU2003259208A1 AU2003259208A AU2003259208A AU2003259208A1 AU 2003259208 A1 AU2003259208 A1 AU 2003259208A1 AU 2003259208 A AU2003259208 A AU 2003259208A AU 2003259208 A AU2003259208 A AU 2003259208A AU 2003259208 A1 AU2003259208 A1 AU 2003259208A1
Authority
AU
Australia
Prior art keywords
imaging
drug delivery
conjugated lysine
lysine copolymers
copolymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003259208A
Other languages
English (en)
Inventor
Egidijus Edward Uzgiris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Electric Co filed Critical General Electric Co
Publication of AU2003259208A1 publication Critical patent/AU2003259208A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/146—Peptides, e.g. proteins the peptide being a polyamino acid, e.g. poly-lysine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
AU2003259208A 2002-07-31 2003-07-23 Conjugated lysine copolymers for drug delivery and imaging Abandoned AU2003259208A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/209,993 2002-07-31
US10/209,993 US20040022733A1 (en) 2002-07-31 2002-07-31 Conjugated lysine copolymers
PCT/US2003/022913 WO2004011034A1 (en) 2002-07-31 2003-07-23 Conjugated lysine copolymers for drug delivery and imaging

Publications (1)

Publication Number Publication Date
AU2003259208A1 true AU2003259208A1 (en) 2004-02-16

Family

ID=31187190

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003259208A Abandoned AU2003259208A1 (en) 2002-07-31 2003-07-23 Conjugated lysine copolymers for drug delivery and imaging

Country Status (5)

Country Link
US (1) US20040022733A1 (OSRAM)
EP (1) EP1526873A1 (OSRAM)
JP (1) JP2006501204A (OSRAM)
AU (1) AU2003259208A1 (OSRAM)
WO (1) WO2004011034A1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063304A2 (en) * 2003-12-24 2005-07-14 Board Of Regents, The University Of Texas_System Poly (l-glutamic acid) paramagnetic material complex and use as a biodegradable mri contrast agent
US20050271585A1 (en) * 2004-06-07 2005-12-08 General Electric Company Extended conjugated polymers
RU2007140391A (ru) * 2005-04-01 2009-05-10 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем (Us) Поли(пептид) как хелатор: способы получения и применения
CN103394101B (zh) * 2013-06-27 2014-10-29 浙江大学 一种基于赖氨酸的高分子mri造影剂及其制备方法
US10610608B2 (en) 2013-08-01 2020-04-07 Rochester Institute Of Technology Modular imaging agents containing amino acids and peptides
US10927132B2 (en) 2015-02-27 2021-02-23 Rochester Institute Of Technology Transmetalation methods for the synthesis of PET and SPECT imaging agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957939A (en) * 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4431968A (en) * 1982-04-05 1984-02-14 General Electric Company Method of three-dimensional NMR imaging using selective excitation
US4665365A (en) * 1985-01-07 1987-05-12 General Electric Company Method for reversing residual transverse magnetization due to phase-encoding magnetic field gradients
US5554748A (en) * 1989-04-07 1996-09-10 Nycomed Salutar, Inc. Adducts of macrocyclic chelants
US5762909A (en) * 1995-08-31 1998-06-09 General Electric Company Tumor targeting with polymeric molecules having extended conformation
US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
US6121775A (en) * 1998-06-16 2000-09-19 Beth Israel Deaconess Medical Center, Inc. MRI imaging method and apparatus
US6235264B1 (en) * 1999-12-01 2001-05-22 General Electric Company Medical imaging method for characterizing tumor angiogenesis using polymeric contrast agents
US6685915B2 (en) * 1999-12-01 2004-02-03 General Electric Company Extended-linear polymeric contrast agents, and synthesizing methods, for medical imaging

Also Published As

Publication number Publication date
EP1526873A1 (en) 2005-05-04
WO2004011034A1 (en) 2004-02-05
JP2006501204A (ja) 2006-01-12
US20040022733A1 (en) 2004-02-05

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase