AU2003229884A1 - Imidazo-pyridine derivatives as ligands for gaba receptors - Google Patents

Imidazo-pyridine derivatives as ligands for gaba receptors

Info

Publication number
AU2003229884A1
AU2003229884A1 AU2003229884A AU2003229884A AU2003229884A1 AU 2003229884 A1 AU2003229884 A1 AU 2003229884A1 AU 2003229884 A AU2003229884 A AU 2003229884A AU 2003229884 A AU2003229884 A AU 2003229884A AU 2003229884 A1 AU2003229884 A1 AU 2003229884A1
Authority
AU
Australia
Prior art keywords
imidazo
ligands
pyridine derivatives
gaba receptors
gaba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003229884A
Inventor
Frank Burkamp
Leslie Joseph Street
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU2003229884A1 publication Critical patent/AU2003229884A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003229884A 2002-04-11 2003-04-03 Imidazo-pyridine derivatives as ligands for gaba receptors Abandoned AU2003229884A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0208394.7A GB0208394D0 (en) 2002-04-11 2002-04-11 Therapeutic agents
GB0208394.7 2002-04-11
PCT/GB2003/001465 WO2003086406A1 (en) 2002-04-11 2003-04-03 Imidazo-pyridine derivatives as ligands for gaba receptors

Publications (1)

Publication Number Publication Date
AU2003229884A1 true AU2003229884A1 (en) 2003-10-27

Family

ID=9934692

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003229884A Abandoned AU2003229884A1 (en) 2002-04-11 2003-04-03 Imidazo-pyridine derivatives as ligands for gaba receptors

Country Status (3)

Country Link
AU (1) AU2003229884A1 (en)
GB (1) GB0208394D0 (en)
WO (1) WO2003086406A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
WO2007073283A1 (en) 2005-12-20 2007-06-28 Astrazeneca Ab Substituted cinnoline derivatives as gabaa-receptor modulators and method for their synthesis
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
DK3849976T3 (en) 2018-09-13 2023-01-23 Saniona As GABAA receptor ligand

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3150486A1 (en) * 1981-12-19 1983-08-25 Merck Patent Gmbh, 6100 Darmstadt IMIDAZO (4,5-C) PYRIDINE, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DK40192D0 (en) * 1992-03-26 1992-03-26 Neurosearch As IMIDAZOLE COMPOUNDS, THEIR PREPARATION AND USE
AU675484B2 (en) * 1993-03-24 1997-02-06 Neurosearch A/S Benzimidazole compounds, their use and preparation
ATE210132T1 (en) * 1995-04-21 2001-12-15 Neurosearch As BENZMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABAA RECEPTOR COMPLEX
CA2410037C (en) * 2000-05-24 2009-11-03 Merck Sharp & Dohme Limited 3-phenyl-imidazo-pyrimidine derivatives as ligands for gaba receptors
JP2002193710A (en) * 2000-12-25 2002-07-10 Kumiai Chem Ind Co Ltd Pyrimidine or triazine derivative and fungicide for agriculture and horticulture
BR0207975A (en) * 2001-03-15 2004-06-15 Basf Ag Compound, process for preparing 5 phenylpyridines, intermediate product, suitable agent for combating phytopathogenic harmful fungi, and process for combating phytopathogenic harmful fungi

Also Published As

Publication number Publication date
WO2003086406A1 (en) 2003-10-23
GB0208394D0 (en) 2002-05-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase