AU2002364612A1 - METHODS AND MATERIALS FOR MODULATING ENaC-BETA - Google Patents

METHODS AND MATERIALS FOR MODULATING ENaC-BETA

Info

Publication number
AU2002364612A1
AU2002364612A1 AU2002364612A AU2002364612A AU2002364612A1 AU 2002364612 A1 AU2002364612 A1 AU 2002364612A1 AU 2002364612 A AU2002364612 A AU 2002364612A AU 2002364612 A AU2002364612 A AU 2002364612A AU 2002364612 A1 AU2002364612 A1 AU 2002364612A1
Authority
AU
Australia
Prior art keywords
beta
materials
methods
enac
modulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002364612A
Other languages
English (en)
Other versions
AU2002364612A8 (en
Inventor
Ulf N.G. Arvidsson
Lucy Vulchanova Hart
Samuel J. Shuster
Laura S. Stone
Hong-Yan Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALGOS THERAPEUTICS Inc
Original Assignee
ALGOS THERAPEUTICS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALGOS THERAPEUTICS Inc filed Critical ALGOS THERAPEUTICS Inc
Publication of AU2002364612A1 publication Critical patent/AU2002364612A1/en
Publication of AU2002364612A8 publication Critical patent/AU2002364612A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002364612A 2001-12-31 2002-12-31 METHODS AND MATERIALS FOR MODULATING ENaC-BETA Abandoned AU2002364612A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34606901P 2001-12-31 2001-12-31
US60/346,069 2001-12-31
PCT/US2002/041850 WO2003057847A2 (en) 2001-12-31 2002-12-31 METHODS AND MATERIALS FOR MODULATING ENaC-BETA

Publications (2)

Publication Number Publication Date
AU2002364612A1 true AU2002364612A1 (en) 2003-07-24
AU2002364612A8 AU2002364612A8 (en) 2003-07-24

Family

ID=23357796

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002364612A Abandoned AU2002364612A1 (en) 2001-12-31 2002-12-31 METHODS AND MATERIALS FOR MODULATING ENaC-BETA

Country Status (3)

Country Link
EP (1) EP1478655A4 (de)
AU (1) AU2002364612A1 (de)
WO (1) WO2003057847A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1190249A2 (de) 1999-06-08 2002-03-27 University Of Iowa Research Foundation Verbindungen und methoden zur erhöhung von raav-transduktion
AR066984A1 (es) 2007-06-15 2009-09-23 Novartis Ag Inhibicion de la expresion de la subunidad alfa del canal epitelial de sodio (enac) por medio de arni (arn de interferencia)
CN102985544A (zh) 2010-04-23 2013-03-20 诺瓦提斯公司 治疗β-ENaC-相关疾病的有机组合物
WO2013155406A1 (en) * 2012-04-12 2013-10-17 The Chinese University Of Hong Kong Contragestion and treating inflammation by modulating sodium channel activity in the epithelium
US11702672B2 (en) 2016-02-08 2023-07-18 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
CA3016985C (en) 2016-03-07 2023-07-04 University Of Iowa Research Foundation Aav-mediated expression using a synthetic promoter and enhancer
KR20200024793A (ko) 2017-07-06 2020-03-09 애로우헤드 파마슈티컬스 인코포레이티드 알파-ENaC의 발현을 억제하기 위한 RNAi 작용제 및 사용 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0975798A1 (de) * 1997-03-11 2000-02-02 Yale University Verfahren zur diagnose und behandlung von pathalogischen zustaenden in zusammenhang mit ionentransportdefizienzen so als pseudohypoaldostereonismus typ i
US20030077773A1 (en) * 2000-12-06 2003-04-24 Brandon Rhonda C. Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Also Published As

Publication number Publication date
WO2003057847A3 (en) 2003-12-11
WO2003057847A2 (en) 2003-07-17
EP1478655A4 (de) 2006-05-10
EP1478655A2 (de) 2004-11-24
WO2003057847A8 (en) 2004-01-15
AU2002364612A8 (en) 2003-07-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase