AU2002342858A1 - Human high-affinity antibody fragments for essential proteins of the hepatitis-c virus - Google Patents

Human high-affinity antibody fragments for essential proteins of the hepatitis-c virus

Info

Publication number
AU2002342858A1
AU2002342858A1 AU2002342858A AU2002342858A AU2002342858A1 AU 2002342858 A1 AU2002342858 A1 AU 2002342858A1 AU 2002342858 A AU2002342858 A AU 2002342858A AU 2002342858 A AU2002342858 A AU 2002342858A AU 2002342858 A1 AU2002342858 A1 AU 2002342858A1
Authority
AU
Australia
Prior art keywords
hepatitis
virus
antibody fragments
affinity antibody
human high
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002342858A
Inventor
Olga Artsaenko
Dieter Hausslinger
Tobias Heintges
Kathi Tessmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2002342858A1 publication Critical patent/AU2002342858A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
AU2002342858A 2001-05-11 2002-05-13 Human high-affinity antibody fragments for essential proteins of the hepatitis-c virus Abandoned AU2002342858A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10123041A DE10123041A1 (en) 2001-05-11 2001-05-11 New single-chain human antibody fragment, useful for treating or diagnosing hepatitis C virus infection, has affinity for an essential viral protein
DE10123041.9 2001-05-11
PCT/EP2002/005227 WO2002093519A2 (en) 2001-05-11 2002-05-13 Human high-affinity antibody fragments for essential proteins of the hepatitis-c virus

Publications (1)

Publication Number Publication Date
AU2002342858A1 true AU2002342858A1 (en) 2002-11-25

Family

ID=7684487

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002342858A Abandoned AU2002342858A1 (en) 2001-05-11 2002-05-13 Human high-affinity antibody fragments for essential proteins of the hepatitis-c virus

Country Status (3)

Country Link
AU (1) AU2002342858A1 (en)
DE (1) DE10123041A1 (en)
WO (1) WO2002093519A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60237704D1 (en) 2001-10-16 2010-10-28 Government Of The Us Secretary NEUTRALIZING ANTIBODIES TO HIV WITH A WIDE CROSS-REACTION SELECTED BY ENV-CD4-CO RECEPTOR COMPLEXES
EP1504034B1 (en) 2002-05-06 2012-12-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Identification of novel broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies
WO2003092630A2 (en) 2002-05-06 2003-11-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Identification of novel broadly cross-reactive neutralizing human monoclonal antibodies using sequential antigen panning of phage display libraries
CA2553788A1 (en) * 2003-09-29 2006-07-06 The Government Of The United States Of America, As Represented By The Se Cretary, Department Of Health And Human Services Immunoglobulins whith potent and broad antiviral activity
EP2338997A1 (en) * 2005-03-25 2011-06-29 National Research Council Of Canada Method for isolation of soluble polypeptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171782B1 (en) * 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
US6190864B1 (en) * 1991-05-08 2001-02-20 Chiron Corporation HCV genomic sequences for diagnostics and therapeutics
DE19531226C1 (en) * 1995-08-24 1997-04-03 Immuno Ag Pharmaceutical compsn. for prevention or treatment of viral disease

Also Published As

Publication number Publication date
DE10123041A1 (en) 2002-11-28
WO2002093519A2 (en) 2002-11-21
WO2002093519A3 (en) 2003-10-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase