AU2002340778B2 - Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides - Google Patents

Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides Download PDF

Info

Publication number
AU2002340778B2
AU2002340778B2 AU2002340778A AU2002340778A AU2002340778B2 AU 2002340778 B2 AU2002340778 B2 AU 2002340778B2 AU 2002340778 A AU2002340778 A AU 2002340778A AU 2002340778 A AU2002340778 A AU 2002340778A AU 2002340778 B2 AU2002340778 B2 AU 2002340778B2
Authority
AU
Australia
Prior art keywords
factor vii
pal
related polypeptide
pai
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002340778A
Other languages
English (en)
Other versions
AU2002340778A1 (en
Inventor
Rasmus Rojkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Novo Nordisk Health Care AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Health Care AG filed Critical Novo Nordisk Health Care AG
Publication of AU2002340778A1 publication Critical patent/AU2002340778A1/en
Application granted granted Critical
Publication of AU2002340778B2 publication Critical patent/AU2002340778B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2002340778A 2001-11-09 2002-11-05 Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides Ceased AU2002340778B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101671 2001-11-09
DKPA200101671 2001-11-09
PCT/DK2002/000735 WO2003039580A1 (en) 2001-11-09 2002-11-05 Pharmaceutical composition comprising factor vii polypeptides and pai-1 polypeptides

Publications (2)

Publication Number Publication Date
AU2002340778A1 AU2002340778A1 (en) 2003-07-24
AU2002340778B2 true AU2002340778B2 (en) 2007-08-02

Family

ID=8160829

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002340778A Ceased AU2002340778B2 (en) 2001-11-09 2002-11-05 Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides

Country Status (15)

Country Link
EP (1) EP1446146A1 (ja)
JP (1) JP2005510514A (ja)
KR (1) KR20050043733A (ja)
CN (1) CN1596122A (ja)
AU (1) AU2002340778B2 (ja)
BR (1) BR0213952A (ja)
CA (1) CA2464614A1 (ja)
CZ (1) CZ2004535A3 (ja)
HU (1) HUP0401959A3 (ja)
IL (1) IL161523A0 (ja)
NO (1) NO20042379L (ja)
PL (1) PL370118A1 (ja)
RU (1) RU2304980C2 (ja)
WO (1) WO2003039580A1 (ja)
ZA (1) ZA200403270B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009045412A2 (en) * 2007-10-01 2009-04-09 American Diagnostica, Inc. Methods of treatment using modified plasminogen activator inhibitor type-1 molecules
WO2020103930A1 (zh) * 2018-11-22 2020-05-28 上海科技大学 噻唑并环类化合物、其制备方法、中间体和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7907398A (en) * 1997-06-23 1999-01-04 Novo Nordisk A/S Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function
AT409335B (de) * 1998-11-10 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend einen rezeptor-antagonisten zur behandlung von blutgerinnungsstörungen
DE60143292D1 (de) * 2000-05-03 2010-12-02 Novo Nordisk Healthcare Ag Varianten des menschlichen Koagulationsfaktors VII

Also Published As

Publication number Publication date
KR20050043733A (ko) 2005-05-11
JP2005510514A (ja) 2005-04-21
RU2004117535A (ru) 2005-04-10
HUP0401959A2 (hu) 2004-12-28
IL161523A0 (en) 2004-09-27
WO2003039580A1 (en) 2003-05-15
CZ2004535A3 (cs) 2005-01-12
HUP0401959A3 (en) 2009-03-30
CN1596122A (zh) 2005-03-16
CA2464614A1 (en) 2003-05-15
BR0213952A (pt) 2004-08-31
ZA200403270B (en) 2004-11-08
RU2304980C2 (ru) 2007-08-27
NO20042379L (no) 2004-06-08
PL370118A1 (en) 2005-05-16
EP1446146A1 (en) 2004-08-18

Similar Documents

Publication Publication Date Title
US7125846B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
US20050267014A1 (en) Pharmaceutical composition comprising factor VII polypeptides and tranexamic acid
US20080058266A1 (en) Pharmaceutical Compositions Comprising Factor VII Polypeptides and Factor XI Polypeptides
US7078479B2 (en) Pharmaceutical composition comprising factor VII polypeptides and alpha2-antiplasmin polypeptides
US20060293241A1 (en) Pharmaceutical composition comprising a factor VII polypeptide and epsilon-aminocaproic acid
US20080069810A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and TAFI Polypeptides
US20070219135A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and PAI-1 Polypeptide
US20030119743A1 (en) Pharmaceutical composition comprising factor VII polypeptides and tissue plasminogen inhibitors
AU2002354846B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20030119741A1 (en) Pharmaceutical composition comprising factor VII polypeptides and aprotinin polypeptides
AU2002354846A1 (en) Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20080075709A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides And Thrombomodulin Polypeptides
US20060025336A1 (en) Pharmaceutical compositions comprising combinations of factor VII polypeptides and aprotinin polypeptides
AU2002340779B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
EP1446155A1 (en) Pharmaceutical composition comprising factor vii polypeptides and aprotinin polypeptides
AU2002340779A1 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
AU2002340778B2 (en) Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides
EP1446147A1 (en) Pharmaceutical composition comprising factor vii polypeptides and tranexamic acid
WO2003039579A1 (en) Pharmaceutical composition comprising factor vii polypeptides and tafi polypeptides
AU2002340778A1 (en) Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides
WO2003039588A1 (en) Pharmaceutical composition comprising factor vii polypeptides and tissue plasminogen inhibitors
EP1446154A1 (en) Pharmaceutical composition comprising factor vii polypeptides and alpha2 -antiplasmin polypeptides
EP1446151A1 (en) Pharmaceutical composition comprising factor vii polypeptides and thrombomodulin polypeptides

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired