AU2002250401A1 - Histone deacetylase inhibitors - Google Patents
Histone deacetylase inhibitorsInfo
- Publication number
- AU2002250401A1 AU2002250401A1 AU2002250401A AU2002250401A AU2002250401A1 AU 2002250401 A1 AU2002250401 A1 AU 2002250401A1 AU 2002250401 A AU2002250401 A AU 2002250401A AU 2002250401 A AU2002250401 A AU 2002250401A AU 2002250401 A1 AU2002250401 A1 AU 2002250401A1
- Authority
- AU
- Australia
- Prior art keywords
- histone deacetylase
- deacetylase inhibitors
- inhibitors
- histone
- deacetylase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81294001A | 2001-03-27 | 2001-03-27 | |
US09/812,944 US6495719B2 (en) | 2001-03-27 | 2001-03-27 | Histone deacetylase inhibitors |
US09/812,944 | 2001-03-27 | ||
US09/812,940 | 2001-03-27 | ||
US09/812,945 US7312247B2 (en) | 2001-03-27 | 2001-03-27 | Histone deacetylase inhibitors |
US09/812,945 | 2001-03-27 | ||
US10/025,947 | 2001-12-26 | ||
US10/025,947 US8026280B2 (en) | 2001-03-27 | 2001-12-26 | Histone deacetylase inhibitors |
PCT/US2002/008836 WO2002076941A2 (en) | 2001-03-27 | 2002-03-25 | Histone deacetylase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002250401A1 true AU2002250401A1 (en) | 2002-10-08 |
Family
ID=27487458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002250401A Abandoned AU2002250401A1 (en) | 2001-03-27 | 2002-03-25 | Histone deacetylase inhibitors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1408946A4 (en) |
AU (1) | AU2002250401A1 (en) |
CA (1) | CA2442366C (en) |
WO (1) | WO2002076941A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003226408B2 (en) * | 2002-04-15 | 2007-06-14 | Sloan-Kettering Institute For Cancer Research | Combination therapy for the treatment of cancer |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1291015A1 (en) | 2001-09-10 | 2003-03-12 | Lunamed AG | Dosage forms having prolonged active ingredient release |
GB0226855D0 (en) | 2002-11-18 | 2002-12-24 | Queen Mary & Westfield College | Histone deacetylase inhibitors |
EP1567142A4 (en) * | 2002-11-20 | 2005-12-14 | Errant Gene Therapeutics Llc | Treatment of lung cells with histone deacetylase inhibitors |
JP4790594B2 (en) | 2003-02-25 | 2011-10-12 | トポターゲット ユーケー リミテッド | Hydroxamic acid compounds containing bicyclic heteroaryl groups as HDAC inhibitors |
US7842835B2 (en) | 2003-07-07 | 2010-11-30 | Georgetown University | Histone deacetylase inhibitors and methods of use thereof |
AR050552A1 (en) * | 2004-09-02 | 2006-11-01 | Osi Pharm Inc | MERCAPTOAMIDS AS INHIBITORS OF HISTONA DEACETILASE |
WO2006029818A2 (en) * | 2004-09-16 | 2006-03-23 | Dsm Ip Assets B.V. | Cosmetic compositions containing an hydroxamic acid compound optionally in combination with a retinoid |
WO2007011626A2 (en) | 2005-07-14 | 2007-01-25 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
GB0620823D0 (en) | 2006-10-19 | 2006-11-29 | Univ London | Histone deacetylase inhibitors |
JP2019189648A (en) * | 2019-07-08 | 2019-10-31 | 国立大学法人東京農工大学 | Cis-cinnamic acid analog and gravitropism regulator |
CN110523541B (en) * | 2019-09-04 | 2021-09-28 | 中南大学 | Alkyl thioether ether ethyl hydroximic acid medicament and preparation method and application thereof |
CN114805235B (en) * | 2022-05-09 | 2024-04-23 | 江苏中旗科技股份有限公司 | Synthetic preparation method of polysubstituted isoxazolidinone and intermediate thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886278A (en) * | 1973-08-22 | 1975-05-27 | Mead Johnson & Co | Ammonium carboxylate sebum inhibition process |
JPS6054339A (en) * | 1983-09-05 | 1985-03-28 | Kuraray Co Ltd | Preparation of unsaturated carboxylic acid ester |
JP3065636B2 (en) * | 1989-06-29 | 2000-07-17 | 塩野義製薬株式会社 | [Di-tert-butyl (hydroxy) phenylthio] substituted hydroxamic acid derivatives |
GB9614366D0 (en) * | 1996-07-09 | 1996-09-04 | Smithkline Beecham Spa | Novel compounds |
US6110955A (en) * | 1997-03-11 | 2000-08-29 | Beacon Laboratories, Inc. | Metabolically stabilized oxyalkylene esters and uses thereof |
US6147224A (en) * | 1998-10-01 | 2000-11-14 | Allergan Sales, Inc. | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors |
-
2002
- 2002-03-25 AU AU2002250401A patent/AU2002250401A1/en not_active Abandoned
- 2002-03-25 EP EP02719311A patent/EP1408946A4/en not_active Withdrawn
- 2002-03-25 CA CA2442366A patent/CA2442366C/en not_active Expired - Fee Related
- 2002-03-25 WO PCT/US2002/008836 patent/WO2002076941A2/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003226408B2 (en) * | 2002-04-15 | 2007-06-14 | Sloan-Kettering Institute For Cancer Research | Combination therapy for the treatment of cancer |
Also Published As
Publication number | Publication date |
---|---|
EP1408946A4 (en) | 2004-06-09 |
CA2442366C (en) | 2012-09-25 |
CA2442366A1 (en) | 2002-10-03 |
EP1408946A2 (en) | 2004-04-21 |
WO2002076941A2 (en) | 2002-10-03 |
WO2002076941A3 (en) | 2004-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |