AU2002239578A1 - Enhanced efficacy and safety of genotoxic therapy by p38 mapk modulation - Google Patents
Enhanced efficacy and safety of genotoxic therapy by p38 mapk modulationInfo
- Publication number
- AU2002239578A1 AU2002239578A1 AU2002239578A AU3957802A AU2002239578A1 AU 2002239578 A1 AU2002239578 A1 AU 2002239578A1 AU 2002239578 A AU2002239578 A AU 2002239578A AU 3957802 A AU3957802 A AU 3957802A AU 2002239578 A1 AU2002239578 A1 AU 2002239578A1
- Authority
- AU
- Australia
- Prior art keywords
- mapk
- modulation
- safety
- enhanced efficacy
- genotoxic therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/14—Post-translational modifications [PTMs] in chemical analysis of biological material phosphorylation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24691200P | 2000-11-07 | 2000-11-07 | |
US60/246,912 | 2000-11-07 | ||
PCT/US2001/047669 WO2002038143A2 (en) | 2000-11-07 | 2001-11-06 | Enhanced efficacy and safety of genotoxic therapy by p38 mapk modulation |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002239578A1 true AU2002239578A1 (en) | 2002-05-21 |
Family
ID=22932754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002239578A Abandoned AU2002239578A1 (en) | 2000-11-07 | 2001-11-06 | Enhanced efficacy and safety of genotoxic therapy by p38 mapk modulation |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002239578A1 (en) |
WO (1) | WO2002038143A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1709965A3 (en) | 2001-07-11 | 2006-12-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Methods of treating cytokine mediate diseases |
WO2005077983A2 (en) * | 2004-02-05 | 2005-08-25 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Modulating p38 kinase activity |
FR2874619B1 (en) * | 2004-08-25 | 2006-11-17 | Centre Nat Rech Scient Cnrse | NOVEL PHOSPHORYLATED PHOSPHATASE SEQUENCES OF CDC25B PHOSPHATASE, ANTIBODIES DIRECTED THEREFROM AND USES THEREOF |
CN109528720B (en) * | 2019-01-08 | 2021-03-30 | 浙江大学 | Application of SB203580 in preparation of antitumor drugs and antitumor drugs |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5863729A (en) * | 1996-07-09 | 1999-01-26 | Washington University | DNA sequences encoding human TcAK1 kinase |
AU6394500A (en) * | 1999-07-30 | 2001-02-19 | Basf Bioresearch Corporation | Native cdc25 substrates, compositions and uses related thereto |
WO2001057206A2 (en) * | 2000-02-03 | 2001-08-09 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for the inhibition of checkpoint kinase-1 (chk 1) enzyme |
-
2001
- 2001-11-06 AU AU2002239578A patent/AU2002239578A1/en not_active Abandoned
- 2001-11-06 WO PCT/US2001/047669 patent/WO2002038143A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002038143A2 (en) | 2002-05-16 |
WO2002038143A3 (en) | 2003-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001297911A1 (en) | Magnetic therapy devices and methods | |
EP1304137A3 (en) | Anti-tachycardia pacing methods and devices | |
AU2002218012A1 (en) | Electromagnetically induced anesthesia and sensory stimulation | |
AU2001260513A1 (en) | Microcapsule well treatment | |
AU2001275340A1 (en) | Integrated active flux microfluidic devices and methods | |
WO2003028558A8 (en) | Methods and devices for heart valve treatments | |
AU2001253479A1 (en) | Targeted therapeutic agent release devices and methods of making and using the same | |
AU2003256555A1 (en) | Controlled delivery of active ingredients and sensory markers | |
AU2002356530A1 (en) | Medical devices comprising nanomaterials and therapeutic methods utilizing the same | |
HK1068546A1 (en) | Combination therapy comprising zd6474 and taxane | |
AUPR839001A0 (en) | Dosage form, device and methods of treatment | |
AU2002346504A1 (en) | Therapeutic protein and treatments | |
AU2002332841A1 (en) | Amusement rides and methods | |
AU2001233296A1 (en) | Establishing and maintaining therapeutic hypothermia | |
AU2002254342A1 (en) | Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same | |
AU2001265253A1 (en) | Treatment of hiv using hyperthermia | |
AU2002252976A1 (en) | Hydrazones and their therapeutic use | |
AU2002258600A1 (en) | Uses of targeted oxidative therapeutic formulation in arteriosclerosis | |
EP1379236A4 (en) | Treatment of tics, tremors and related disorders | |
AU2002231206A1 (en) | Treatment of depression | |
AU2001222215A1 (en) | Lumbago treating girdle | |
AU2002359618A1 (en) | Medicinal compositions and therapeutic methods | |
AUPR736801A0 (en) | Advanced games and puzzles | |
AU2002239578A1 (en) | Enhanced efficacy and safety of genotoxic therapy by p38 mapk modulation | |
AU2002227247A1 (en) | Biofilm therapy process and elements |