AU2002217078A1 - Urea and urethane derivatives as integrin inhibitors - Google Patents
Urea and urethane derivatives as integrin inhibitorsInfo
- Publication number
- AU2002217078A1 AU2002217078A1 AU2002217078A AU1707802A AU2002217078A1 AU 2002217078 A1 AU2002217078 A1 AU 2002217078A1 AU 2002217078 A AU2002217078 A AU 2002217078A AU 1707802 A AU1707802 A AU 1707802A AU 2002217078 A1 AU2002217078 A1 AU 2002217078A1
- Authority
- AU
- Australia
- Prior art keywords
- urea
- integrin inhibitors
- urethane derivatives
- urethane
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10063173A DE10063173A1 (en) | 2000-12-18 | 2000-12-18 | Urea and urethane derivatives |
DE10063173 | 2000-12-18 | ||
PCT/EP2001/014039 WO2002050039A1 (en) | 2000-12-18 | 2001-11-30 | Urea and urethane derivatives as integrin inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002217078A1 true AU2002217078A1 (en) | 2002-07-01 |
Family
ID=7667710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002217078A Abandoned AU2002217078A1 (en) | 2000-12-18 | 2001-11-30 | Urea and urethane derivatives as integrin inhibitors |
Country Status (23)
Country | Link |
---|---|
US (1) | US7135587B2 (en) |
EP (1) | EP1343764B1 (en) |
JP (1) | JP4216071B2 (en) |
KR (1) | KR20030063432A (en) |
CN (1) | CN1481364A (en) |
AR (1) | AR035608A1 (en) |
AT (1) | ATE274497T1 (en) |
AU (1) | AU2002217078A1 (en) |
BR (1) | BR0116202A (en) |
CA (1) | CA2431974C (en) |
CZ (1) | CZ20031775A3 (en) |
DE (2) | DE10063173A1 (en) |
DK (1) | DK1343764T3 (en) |
ES (1) | ES2227063T3 (en) |
HU (1) | HUP0302753A3 (en) |
MX (1) | MXPA03005431A (en) |
NO (1) | NO20032754D0 (en) |
PL (1) | PL361745A1 (en) |
PT (1) | PT1343764E (en) |
RU (1) | RU2003121015A (en) |
SK (1) | SK8182003A3 (en) |
WO (1) | WO2002050039A1 (en) |
ZA (1) | ZA200305550B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10204789A1 (en) | 2002-02-06 | 2003-08-14 | Merck Patent Gmbh | Inhibitors of the integrin alpha¶v¶beta6 |
NZ535425A (en) | 2002-03-13 | 2008-05-30 | Biogen Idec Inc | Anti-alphavbeta6 antibodies |
DE602004014795D1 (en) * | 2003-10-01 | 2008-08-14 | Merck Patent Gmbh | ALFAVBETA3 AND ALFAVBETA6 INTEGRIN ANTAGONISTS AS ANTIFIBROTIC AGENTS |
CN102875681A (en) | 2005-07-08 | 2013-01-16 | 拜奥根Idec马萨诸塞公司 | Anti-alpha v beta 6 antibodies and uses thereof |
EP2046374A4 (en) | 2006-07-10 | 2010-05-05 | Biogen Idec Inc | Compositions and methods for inhibiting growth of smad4-deficient cancers |
AU2007354317A1 (en) * | 2006-10-19 | 2008-12-04 | Biogen Idec Ma Inc. | Treatment and prevention of chronic asthma using antagonists of integrin alphaVbeta6 |
AT509266B1 (en) * | 2009-12-28 | 2014-07-15 | Tech Universität Wien | SUBSTITUTED PYRIDINES AND PYRIMIDINES |
CN102353728B (en) * | 2011-06-29 | 2013-03-27 | 中国食品发酵工业研究院 | Rapid detection method for production process quality control of yellow wine |
US10035859B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
US10035860B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
NZ740675A (en) | 2015-10-23 | 2024-02-23 | Vifor Int Ag | Novel ferroportin inhibitors |
JOP20180036A1 (en) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | Novel ferroportin-inhibitor salts |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306840B1 (en) | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
KR20010042704A (en) * | 1998-04-16 | 2001-05-25 | 데이비드 비. 맥윌리암스 | N,N-Disubstituted amides that inhibit the binding of integrins to their receptors |
GB9909409D0 (en) | 1999-04-24 | 1999-06-23 | Zeneca Ltd | Chemical compounds |
DE19939980A1 (en) * | 1999-08-24 | 2001-03-01 | Merck Patent Gmbh | Inhibitors of the integrin alphavbeta¶3¶ |
-
2000
- 2000-12-18 DE DE10063173A patent/DE10063173A1/en not_active Withdrawn
-
2001
- 2001-11-30 JP JP2002551536A patent/JP4216071B2/en not_active Expired - Fee Related
- 2001-11-30 CA CA2431974A patent/CA2431974C/en not_active Expired - Fee Related
- 2001-11-30 SK SK818-2003A patent/SK8182003A3/en unknown
- 2001-11-30 HU HU0302753A patent/HUP0302753A3/en unknown
- 2001-11-30 CZ CZ20031775A patent/CZ20031775A3/en unknown
- 2001-11-30 MX MXPA03005431A patent/MXPA03005431A/en unknown
- 2001-11-30 WO PCT/EP2001/014039 patent/WO2002050039A1/en not_active Application Discontinuation
- 2001-11-30 US US10/450,855 patent/US7135587B2/en not_active Expired - Fee Related
- 2001-11-30 DE DE60105192T patent/DE60105192T2/en not_active Expired - Lifetime
- 2001-11-30 CN CNA01820791XA patent/CN1481364A/en active Pending
- 2001-11-30 DK DK01271360T patent/DK1343764T3/en active
- 2001-11-30 KR KR10-2003-7008122A patent/KR20030063432A/en not_active Application Discontinuation
- 2001-11-30 RU RU2003121015/04A patent/RU2003121015A/en not_active Application Discontinuation
- 2001-11-30 PL PL01361745A patent/PL361745A1/en unknown
- 2001-11-30 BR BR0116202-0A patent/BR0116202A/en not_active Application Discontinuation
- 2001-11-30 AU AU2002217078A patent/AU2002217078A1/en not_active Abandoned
- 2001-11-30 EP EP01271360A patent/EP1343764B1/en not_active Expired - Lifetime
- 2001-11-30 PT PT01271360T patent/PT1343764E/en unknown
- 2001-11-30 ES ES01271360T patent/ES2227063T3/en not_active Expired - Lifetime
- 2001-11-30 AT AT01271360T patent/ATE274497T1/en not_active IP Right Cessation
- 2001-12-14 AR ARP010105796A patent/AR035608A1/en unknown
-
2003
- 2003-06-17 NO NO20032754A patent/NO20032754D0/en unknown
- 2003-07-17 ZA ZA200305550A patent/ZA200305550B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE274497T1 (en) | 2004-09-15 |
CA2431974C (en) | 2010-08-17 |
WO2002050039A1 (en) | 2002-06-27 |
US20040063644A1 (en) | 2004-04-01 |
SK8182003A3 (en) | 2003-10-07 |
NO20032754L (en) | 2003-06-17 |
MXPA03005431A (en) | 2003-09-10 |
HUP0302753A2 (en) | 2003-12-29 |
CN1481364A (en) | 2004-03-10 |
AR035608A1 (en) | 2004-06-16 |
DE60105192T2 (en) | 2005-09-08 |
DE60105192D1 (en) | 2004-09-30 |
DK1343764T3 (en) | 2004-12-06 |
DE10063173A1 (en) | 2002-06-20 |
JP2004516282A (en) | 2004-06-03 |
CA2431974A1 (en) | 2002-06-27 |
CZ20031775A3 (en) | 2003-09-17 |
HUP0302753A3 (en) | 2005-03-29 |
PT1343764E (en) | 2005-01-31 |
ZA200305550B (en) | 2004-10-18 |
JP4216071B2 (en) | 2009-01-28 |
ES2227063T3 (en) | 2005-04-01 |
RU2003121015A (en) | 2005-02-10 |
EP1343764B1 (en) | 2004-08-25 |
NO20032754D0 (en) | 2003-06-17 |
US7135587B2 (en) | 2006-11-14 |
KR20030063432A (en) | 2003-07-28 |
EP1343764A1 (en) | 2003-09-17 |
PL361745A1 (en) | 2004-10-04 |
BR0116202A (en) | 2003-12-23 |
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