AU2001293777A1 - Support device for a preparation for the separation of individual objects from the preparation by means of laser irradiation - Google Patents

Support device for a preparation for the separation of individual objects from the preparation by means of laser irradiation

Info

Publication number
AU2001293777A1
AU2001293777A1 AU2001293777A AU9377701A AU2001293777A1 AU 2001293777 A1 AU2001293777 A1 AU 2001293777A1 AU 2001293777 A AU2001293777 A AU 2001293777A AU 9377701 A AU9377701 A AU 9377701A AU 2001293777 A1 AU2001293777 A1 AU 2001293777A1
Authority
AU
Australia
Prior art keywords
preparation
biological
laser light
support device
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001293777A
Inventor
Karin Schutze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PALM Microlaser Technologies GmbH
Original Assignee
PALM Microlaser Technologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PALM Microlaser Technologies GmbH filed Critical PALM Microlaser Technologies GmbH
Publication of AU2001293777A1 publication Critical patent/AU2001293777A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N2001/045—Laser ablation; Microwave vaporisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833—Collecting samples on a sticky, tacky, adhesive surface
    • G01N2001/284—Collecting samples on a sticky, tacky, adhesive surface using local activation of adhesive, i.e. Laser Capture Microdissection

Landscapes

  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Removal Of Insulation Or Armoring From Wires Or Cables (AREA)

Abstract

In order to separate individual, in particular biological, objects from a, in particular biological, preparation the use of a support device is proposed in which a laser light absorbent membrane ( 1 ), for example of polyester or polyethylene-naphthalene, to which the biological preparation for processing is to be applied is retained and tensioned, preferably together with carrier means ( 2 ) located thereunder, for example, a glass object carrier or a thicker membrane, by means of a retaining device ( 3, 4 ) configured in particular as a frame, so that a compact unit is provided. The support device according to the invention is particularly suitable for isolating individual biological objects from a surrounding biological material by means of laser irradiation and for catapulting said biological objects into a collecting device. The combination of a laser light absorbent membrane ( 1 ) and a laser light transparent membrane ( 2 ) as support for the laser light absorbent membrane ( 1 ) is particularly advantageous.
AU2001293777A 2000-08-16 2001-08-16 Support device for a preparation for the separation of individual objects from the preparation by means of laser irradiation Abandoned AU2001293777A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10039979 2000-08-16
DE10039979A DE10039979A1 (en) 2000-08-16 2000-08-16 Carrier device for a preparation for separating individual objects from the preparation by means of laser radiation
PCT/EP2001/009468 WO2002014833A1 (en) 2000-08-16 2001-08-16 Support device for a preparation for the separation of individual objects from the preparation by means of laser irradiation

Publications (1)

Publication Number Publication Date
AU2001293777A1 true AU2001293777A1 (en) 2002-02-25

Family

ID=7652586

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001293777A Abandoned AU2001293777A1 (en) 2000-08-16 2001-08-16 Support device for a preparation for the separation of individual objects from the preparation by means of laser irradiation

Country Status (7)

Country Link
US (1) US7318999B2 (en)
EP (1) EP1309846B1 (en)
JP (1) JP3626952B2 (en)
AT (1) ATE321263T1 (en)
AU (1) AU2001293777A1 (en)
DE (2) DE10039979A1 (en)
WO (1) WO2002014833A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3773831B2 (en) * 2000-10-31 2006-05-10 富士写真フイルム株式会社 Biological sample cutting method and apparatus used therefor
DE10102034A1 (en) * 2001-01-18 2002-08-08 Leica Microsystems Slide, microdissection device with slide and method for microdissection
DE10135091A1 (en) * 2001-07-15 2003-01-30 Universitaetsklinikum Charite Method, device and slide for microdissection
EP1512317B1 (en) * 2002-05-24 2010-07-14 Koninklijke Philips Electronics N.V. Method suitable for transferring a component supported by a carrier to a desired position on a substrate, and a device designed for this
CA2488391A1 (en) * 2002-07-26 2004-02-19 P.A.L.M. Microlaser Technologies Ag Method for the preparation of a biological material for examination with a microscope as well as corresponding arrangement with a biological material prepared in such a manner
DE10234755A1 (en) * 2002-07-30 2004-02-26 Leica Microsystems Wetzlar Gmbh New carrier for a biological sample, to be cut by laser micro-dissection, comprises film which is absorbent to laser light forming the base of a Petri dish
DE10329674B4 (en) * 2003-06-30 2014-08-14 Karsten König Laser method and apparatus for marking and recovering materials, cell constituents, cells and tissue constituents
DE10346458A1 (en) * 2003-10-02 2005-05-12 Leica Microsystems Method for laser microdissection
DE10358566B4 (en) * 2003-12-15 2012-03-01 P.A.L.M. Microlaser Technologies Ag A holding device for holding a biological object receiving means and a corresponding laser microdissection method
DE10358565B4 (en) * 2003-12-15 2007-06-28 P.A.L.M. Microlaser Technologies Ag A receiving element for receiving an object released from a biological mass by means of laser radiation and method for obtaining and processing a biological object
DE102005061561A1 (en) 2005-12-22 2007-06-28 P.A.L.M. Microlaser Technologies Ag Microdessection method for separation of e.g. individual cells, of e.g. biological preparation, involves cutting preparation through laser irradiation to divide cut layer into low cut and non cut sections, where non cut section is removed
US7807108B2 (en) * 2006-09-18 2010-10-05 Leica Microsystems Cms Gmbh Apparatus for receiving biological specimens
DE102008026727B3 (en) 2008-06-04 2009-07-30 Technische Universität Carolo-Wilhelmina Zu Braunschweig Transport system for micro dissection and laser-induced transport of biological material, has driver layer formed of laser light-absorber layer arranged on substrate, and gas discharging layer
DE202008014487U1 (en) * 2008-10-31 2009-01-22 Mmi Ag Petri dish for cell culture and microscopy
JP2015517825A (en) * 2012-05-29 2015-06-25 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ Systems, methods and components for separating cells from fluid samples

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046457A (en) * 1973-12-26 1977-09-06 Polaroid Corporation Polymeric film base carrying fluoropolymer anti-reflection coating
US5589333A (en) * 1992-02-03 1996-12-31 Thomas Jefferson University In situ polymerase chain reaction
US5294695A (en) * 1993-03-15 1994-03-15 Skc Limited Process for preparing polyethylene naphthalate
US5518925A (en) * 1995-06-06 1996-05-21 Becton Dickinson Co Culture slide assembly
WO1997029354A1 (en) * 1996-02-05 1997-08-14 Bayer Aktiengesellschaft Process and device for sorting and for extraction of biological objects arranged on planar means, such as biological cells or cell organelles, histological sections, chromosome particles etc. using laser beams
JP3635777B2 (en) * 1996-03-20 2005-04-06 株式会社堀場製作所 Sample cell
US5859699A (en) * 1997-02-07 1999-01-12 Arcturus Engineering, Inc. Laser capture microdissection analysis vessel
US6495195B2 (en) * 1997-02-14 2002-12-17 Arcturus Engineering, Inc. Broadband absorbing film for laser capture microdissection
ATE246349T1 (en) * 1997-10-18 2003-08-15 Malte Dr Boehm DEVICE FOR HANDLING SAMPLES FOR MEMBRANE-ASSISTED MICRODISCISSION
DE19818425A1 (en) * 1997-10-18 1999-07-15 Malte Dr Med Boehm Microdissection sample handling device for histology or cytology
DE29823783U1 (en) * 1997-10-18 2000-06-08 Boehm Malte Device for handling samples for membrane-based microdissection
JPH11148887A (en) * 1997-11-17 1999-06-02 Japan Science & Technology Corp Cutting method for organism sample as well as method and apparatus for collection of cut piece
EP0993964A3 (en) * 1998-10-16 2000-11-22 Markem Corporation Coatings for marking by laser
WO2000034757A1 (en) * 1998-12-10 2000-06-15 The Government Of The Unites States Of America Represented By The Secretary, Department Of Health And Human Services Designs for non-contact laser capture microdissection
DE10003588C2 (en) * 2000-01-25 2002-10-02 Sl Microtest Wissenschaftliche Method of isolating part of a layer of biological material

Also Published As

Publication number Publication date
EP1309846A1 (en) 2003-05-14
US20030180941A1 (en) 2003-09-25
EP1309846B1 (en) 2006-03-22
JP3626952B2 (en) 2005-03-09
WO2002014833A1 (en) 2002-02-21
DE10039979A1 (en) 2002-03-07
ATE321263T1 (en) 2006-04-15
DE50109312D1 (en) 2006-05-11
JP2004506892A (en) 2004-03-04
US7318999B2 (en) 2008-01-15

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