AU2001292238A1 - Shingolipid ceramide deacylase gene - Google Patents

Shingolipid ceramide deacylase gene

Info

Publication number
AU2001292238A1
AU2001292238A1 AU2001292238A AU9223801A AU2001292238A1 AU 2001292238 A1 AU2001292238 A1 AU 2001292238A1 AU 2001292238 A AU2001292238 A AU 2001292238A AU 9223801 A AU9223801 A AU 9223801A AU 2001292238 A1 AU2001292238 A1 AU 2001292238A1
Authority
AU
Australia
Prior art keywords
nucleic acid
polypeptide
recombinant dna
diseases
shingolipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001292238A
Inventor
Masako Furusato
Makoto Ito
Noriyuki Sueyoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Shuzo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Shuzo Co Ltd filed Critical Takara Shuzo Co Ltd
Publication of AU2001292238A1 publication Critical patent/AU2001292238A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A polypeptide possessing a sphingolipid ceramide deacylase activity; a nucleic acid encoding the polypeptide; a recombinant DNA comprising the nucleic acid; a carrier for introducing into a cell, carrying the nucleic acid or the recombinant DNA; a transformant harboring the nucleic acid or the recombinant DNA; an oligonucleotide probe or primer for the nucleic acid; a method for detecting the nucleic acid using the probe or the primer and a kit usable therefor; an antibody or a fragment thereof against the polypeptide; and a method for detecting the polypeptide using the antibody or a fragment thereof and a kit usable therefor. According to the present invention, there can be applied to engineering of sphingolipids, and to treatments for diseases such as diseases of nervous system (for instance, neurodegenerative diseases and the like), leukemia and wounds.
AU2001292238A 2000-09-26 2001-09-26 Shingolipid ceramide deacylase gene Abandoned AU2001292238A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-293181 2000-09-26
JP2000293181 2000-09-26
PCT/JP2001/008344 WO2002026963A1 (en) 2000-09-26 2001-09-26 Shingolipid ceramide deacylase gene

Publications (1)

Publication Number Publication Date
AU2001292238A1 true AU2001292238A1 (en) 2002-04-08

Family

ID=18776015

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001292238A Abandoned AU2001292238A1 (en) 2000-09-26 2001-09-26 Shingolipid ceramide deacylase gene

Country Status (10)

Country Link
US (1) US7101699B2 (en)
EP (1) EP1329503B1 (en)
JP (1) JP3995591B2 (en)
KR (1) KR100636587B1 (en)
CN (1) CN100497619C (en)
AT (1) ATE423198T1 (en)
AU (1) AU2001292238A1 (en)
DE (1) DE60137702D1 (en)
TW (1) TWI247804B (en)
WO (1) WO2002026963A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007102396A1 (en) * 2006-03-02 2007-09-13 Kyushu University Method for production of labeled sphingolipid

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3909710A1 (en) 1989-03-23 1990-09-27 Boehringer Mannheim Gmbh METHOD FOR EXPRESSING A RECOMBINANT GENE
JP3035602B2 (en) 1992-09-04 2000-04-24 工業技術院長 Process for producing lysosphingolipids and novel Rhodococcus microorganisms used in the process
JPH07107988A (en) 1993-10-13 1995-04-25 Higashimaru Shoyu Kk Production of lysoglycolipid
JP3625244B2 (en) 1996-07-26 2005-03-02 タカラバイオ株式会社 Method for producing lysosphingolipid
DE69503016T2 (en) 1994-07-21 1998-10-15 Takara Shuzo Co Glycolipid ceramide deacylase
JP3669595B2 (en) * 1994-07-21 2005-07-06 タカラバイオ株式会社 Sphingolipid ceramide deacylase
US6428999B1 (en) * 1994-07-21 2002-08-06 Takara Shuzo Co., Ltd. Sphingolipid ceramide N-deacylase, methods for producing sphingolipids and sphingolipid derivatives, and spingolipid ceramide N-deacylase gene
JPH11276177A (en) 1998-03-26 1999-10-12 Takara Shuzo Co Ltd Sphingolipid ceramide n-deacylase gene
EP0940409B1 (en) 1996-07-19 2004-05-12 Takara Shuzo Co. Ltd. Process for the preparation of sphingolipids and sphingolipid derivatives

Also Published As

Publication number Publication date
EP1329503B1 (en) 2009-02-18
JP3995591B2 (en) 2007-10-24
TWI247804B (en) 2006-01-21
US20040106183A1 (en) 2004-06-03
KR100636587B1 (en) 2006-10-19
JPWO2002026963A1 (en) 2004-02-05
CN1527878A (en) 2004-09-08
US7101699B2 (en) 2006-09-05
CN100497619C (en) 2009-06-10
EP1329503A1 (en) 2003-07-23
KR20030040494A (en) 2003-05-22
WO2002026963A1 (en) 2002-04-04
DE60137702D1 (en) 2009-04-02
EP1329503A4 (en) 2004-12-15
ATE423198T1 (en) 2009-03-15

Similar Documents

Publication Publication Date Title
DE69434663D1 (en) NUCLEOTIDE SEQUENCES FOR CONTROLLING THE EXPRESSION OF DNA SEQUENCES IN A CELLULAR HOST
WO2004101760A3 (en) Novel lipolytic enzyme elip
CA2163781A1 (en) Method and Apparatus for Conducting an Array of Chemical Reactions on a Support Surface
DE69840387D1 (en) NIK PROTEIN, NUCLEIC ACID AND METHOD
WO1997035989A3 (en) Cyclic nucleotide phosphodiesterase
NZ296748A (en) Peripheral nervous system specific sodium channel proteins, DNA coding therefor, compositions and methods
WO2003006644A3 (en) Lipase/acyltransferase
DE69808743D1 (en) Netrinrezeptoren
AU1113999A (en) Target sequences for synthetic molecules and methods of using same
ATE325878T1 (en) METHOD FOR PRODUCING OPTICALLY ACTIVE CONNECTIONS
EP0821064A3 (en) Recombinant fructosyl amino acid oxidase
WO1998042827A3 (en) Gene encoding oxalate decarboxylase from aspergillus phoenicis
WO1999010504A3 (en) Caspase-14, an apoptotic protease, nucleic acids encoding and methods of use
ATE360698T1 (en) PROTEIN PARTICIPATING IN ACTIVATION OF NITRILE HYDRATASE, GENE, PLASMID AND METHOD FOR PRODUCING AN AMIDE
AU2001292238A1 (en) Shingolipid ceramide deacylase gene
MX9709338A (en) A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR.
AUPP627498A0 (en) Novel peptides - i
ES2189560A1 (en) Dna polymerase lambda and uses thereof
ATE345382T1 (en) 2,6-BETA-D-FRUCT ANHYDROLASE ENZYME AND METHOD FOR USE THEREOF
MX9701596A (en) A human map kinase homolog.
CA2311646A1 (en) Tsa305 gene
AU5018496A (en) New dna molecules
WO2001049714A3 (en) Nope polypeptides, encoding nucleic acids and methods of use
WO2001081546A3 (en) CeSERT GENES, PROTEINS, AND MODULATORY COMPOUNDS
GB9912179D0 (en) compositions