AU2001287537A1 - Fv constructs with an influenceable affinity for substance that is to be linked - Google Patents

Fv constructs with an influenceable affinity for substance that is to be linked

Info

Publication number
AU2001287537A1
AU2001287537A1 AU2001287537A AU8753701A AU2001287537A1 AU 2001287537 A1 AU2001287537 A1 AU 2001287537A1 AU 2001287537 A AU2001287537 A AU 2001287537A AU 8753701 A AU8753701 A AU 8753701A AU 2001287537 A1 AU2001287537 A1 AU 2001287537A1
Authority
AU
Australia
Prior art keywords
constructs
linked
affinity
substance
influenceable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001287537A
Other languages
English (en)
Inventor
Stefan Dubel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Heidelberg
Original Assignee
Universitaet Heidelberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10044002A external-priority patent/DE10044002A1/de
Application filed by Universitaet Heidelberg filed Critical Universitaet Heidelberg
Publication of AU2001287537A1 publication Critical patent/AU2001287537A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
AU2001287537A 2000-08-11 2001-08-10 Fv constructs with an influenceable affinity for substance that is to be linked Abandoned AU2001287537A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10040046 2000-08-11
DE10040046 2000-08-11
DE10044002 2000-09-05
DE10044002A DE10044002A1 (de) 2000-08-11 2000-09-05 F¶v¶-Konstrukte mit beeinflußbarer Affinität zu einer zu bindenden Substanz
PCT/DE2001/003098 WO2002014371A1 (fr) 2000-08-11 2001-08-10 Structures fv presentant une affinite influençable avec une substance a lier

Publications (1)

Publication Number Publication Date
AU2001287537A1 true AU2001287537A1 (en) 2002-02-25

Family

ID=26006714

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001287537A Abandoned AU2001287537A1 (en) 2000-08-11 2001-08-10 Fv constructs with an influenceable affinity for substance that is to be linked

Country Status (6)

Country Link
US (1) US20050054000A1 (fr)
EP (1) EP1307490B1 (fr)
AT (1) ATE360035T1 (fr)
AU (1) AU2001287537A1 (fr)
DE (1) DE50112379D1 (fr)
WO (1) WO2002014371A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
EP2298815B1 (fr) 2005-07-25 2015-03-11 Emergent Product Development Seattle, LLC Reduction de lymphocytes B au moyen de molecules de liaison specifique de CD37 et specifique de CD20
KR101571027B1 (ko) * 2006-06-12 2015-11-23 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 효과기 기능을 갖는 단일쇄 다가 결합 단백질
US20090148447A1 (en) * 2007-07-06 2009-06-11 Trubion Pharmaceuticals, Inc. Binding Peptides Having a C-terminally Disposed Specific Binding Domain
WO2009126944A1 (fr) * 2008-04-11 2009-10-15 Trubion Pharmaceuticals, Inc. Produits d’immunothérapie de cd37 et combinaison avec un produit chimiothérapique bifonctionnel de celui-ci
US8647829B2 (en) * 2009-02-20 2014-02-11 General Electric Company Switchable affinity binders
SG10202002577XA (en) 2015-09-21 2020-04-29 Aptevo Res & Development Llc Cd3 binding polypeptides
ES2708657T3 (es) 2016-07-29 2019-04-10 Miltenyi Biotec Gmbh Composición y método para afectar la unión de polipéptidos de unión a antígeno a antígenos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6075010A (en) * 1992-06-09 2000-06-13 Neorx Corporation Small molecular weight ligand-hexose containing clearing agents
US4569794A (en) * 1984-12-05 1986-02-11 Eli Lilly And Company Process for purifying proteins and compounds useful in such process
US5594115A (en) * 1990-04-09 1997-01-14 Pharmacia & Upjohn Company Process of purifying recombinant proteins and compounds useful in such process
US5439829A (en) * 1991-01-30 1995-08-08 Eli Lilly And Company Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
DE69708420T2 (de) * 1996-09-09 2002-07-18 Rmf Dictagene S.A., Prilly Herstellung von gereinigten (Poly)Peptiden

Also Published As

Publication number Publication date
ATE360035T1 (de) 2007-05-15
EP1307490B1 (fr) 2007-04-18
US20050054000A1 (en) 2005-03-10
DE50112379D1 (de) 2007-05-31
WO2002014371A1 (fr) 2002-02-21
EP1307490A1 (fr) 2003-05-07

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