AU2001284648A1 - Diagnostic procedures using 129XE spectroscopy characteristic chemical shift to detect pathology in vivo - Google Patents

Diagnostic procedures using 129XE spectroscopy characteristic chemical shift to detect pathology in vivo

Info

Publication number
AU2001284648A1
AU2001284648A1 AU2001284648A AU8464801A AU2001284648A1 AU 2001284648 A1 AU2001284648 A1 AU 2001284648A1 AU 2001284648 A AU2001284648 A AU 2001284648A AU 8464801 A AU8464801 A AU 8464801A AU 2001284648 A1 AU2001284648 A1 AU 2001284648A1
Authority
AU
Australia
Prior art keywords
detecting
interest
hyperpolarized
pathological condition
spectrum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284648A
Other languages
English (en)
Inventor
Bastiaan Driehuys
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medi Physics Inc
Original Assignee
Medi Physics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medi Physics Inc filed Critical Medi Physics Inc
Publication of AU2001284648A1 publication Critical patent/AU2001284648A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/02755—Radioactive tracers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/4625—Processing of acquired signals, e.g. elimination of phase errors, baseline fitting, chemometric analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Signal Processing (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2001284648A 2000-07-13 2001-07-12 Diagnostic procedures using 129XE spectroscopy characteristic chemical shift to detect pathology in vivo Abandoned AU2001284648A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21797100P 2000-07-13 2000-07-13
US60217971 2000-07-13
PCT/US2001/021998 WO2002005709A2 (en) 2000-07-13 2001-07-12 Diagnostic procedures using 129xe spectroscopy characteristic chemical shift to detect pathology in vivo

Publications (1)

Publication Number Publication Date
AU2001284648A1 true AU2001284648A1 (en) 2002-01-30

Family

ID=22813229

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284648A Abandoned AU2001284648A1 (en) 2000-07-13 2001-07-12 Diagnostic procedures using 129XE spectroscopy characteristic chemical shift to detect pathology in vivo

Country Status (6)

Country Link
US (2) US6696040B2 (de)
EP (1) EP1324690A1 (de)
JP (1) JP2004515263A (de)
AU (1) AU2001284648A1 (de)
CA (1) CA2414610A1 (de)
WO (1) WO2002005709A2 (de)

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US6630126B2 (en) * 2000-03-13 2003-10-07 Medi-Physics, Inc. Diagnostic procedures using direct injection of gaseous hyperpolarized 129Xe and associated systems and products
US7179450B2 (en) * 2001-09-20 2007-02-20 Medi-Physics, Inc. Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
CA2421352A1 (en) * 2002-03-08 2003-09-08 Giovanni Battista Mancini (A.K.A. Mancini, G.B. John) Vessel evaluation methods, apparatus, computer-readable media and signals
GB0308586D0 (en) * 2003-04-14 2003-05-21 Amersham Health R & D Ab Method and arrangements in NMR spectroscopy
US20050267689A1 (en) * 2003-07-07 2005-12-01 Maxim Tsypin Method to automatically identify peak and monoisotopic peaks in mass spectral data for biomolecular applications
AU2006207953B2 (en) 2005-01-28 2012-08-23 The Regents Of The University Of California Systems and methods using nuclear magnetic resonance (NMR) spectroscopy to evaluate pain and degenerative properties of tissue
DE102005026604A1 (de) * 2005-06-09 2006-12-14 Membrana Gmbh Verfahren zum Lösen von Gasen mit kurzlebigen physikalischen Eigenschaften in einer Flüssigkeit
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
EP1933714B1 (de) 2005-09-21 2020-03-18 The Regents of The University of California Systeme und zusammensetzungen für die lokale darstellung und behandlung von schmerzen
US7736905B2 (en) 2006-03-31 2010-06-15 Biodesix, Inc. Method and system for determining whether a drug will be effective on a patient with a disease
WO2008042370A1 (en) * 2006-10-03 2008-04-10 Duke University Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri
US20110036453A1 (en) * 2007-08-28 2011-02-17 Ge Healthcare Limited Nozzle for dnp polarizer
WO2010122546A1 (en) * 2009-04-20 2010-10-28 Technion Research & Development Foundation Ltd. Method and device of estimating a dose of ionizing radiation
JP5677770B2 (ja) * 2009-06-25 2015-02-25 オリンパス株式会社 医療診断支援装置、バーチャル顕微鏡システムおよび標本支持部材
US8825131B2 (en) 2009-10-14 2014-09-02 Nocimed, Llc MR spectroscopy system and method for diagnosing painful and non-painful intervertebral discs
US8761860B2 (en) 2009-10-14 2014-06-24 Nocimed, Llc MR spectroscopy system and method for diagnosing painful and non-painful intervertebral discs
US20110208433A1 (en) * 2010-02-24 2011-08-25 Biodesix, Inc. Cancer patient selection for administration of therapeutic agents using mass spectral analysis of blood-based samples
US9625397B2 (en) * 2010-06-18 2017-04-18 Nanyang Technological University Atomic-scaled electronic spectrum information purification
JP2012098159A (ja) * 2010-11-02 2012-05-24 Jeol Resonance Inc Ｎｍｒ装置の静磁場制御方法
US9280718B2 (en) 2010-11-24 2016-03-08 Nocimed, Llc Systems and methods for automated voxelation of regions of interest for magnetic resonance spectroscopy
US8965094B2 (en) 2012-04-14 2015-02-24 Nocimed, Llc Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method
US8660634B2 (en) * 2012-04-23 2014-02-25 The Brigham and Woman's Hospital System and method for improved lung fourier decomposition magnetic resonance imaging
EP4289347A3 (de) 2016-06-19 2024-03-06 Aclarion, Inc. Magnetresonanz-spektroskopiesystem und verfahren zur diagnose von schmerz oder infektionen im zusammenhang mit propionsäure
US10677874B2 (en) * 2018-02-20 2020-06-09 Wisconsin Alumni Research Foundation System and method for control of hyperpolarized gas-phase contamination in spectroscopic magnetic resonance imaging
US11944424B2 (en) 2018-05-18 2024-04-02 Duke University Dynamic 129Xe gas exchange spectroscopy

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Also Published As

Publication number Publication date
US7357917B2 (en) 2008-04-15
WO2002005709A8 (en) 2003-10-23
WO2002005709A9 (en) 2003-04-10
US20040247526A1 (en) 2004-12-09
WO2002005709A2 (en) 2002-01-24
CA2414610A1 (en) 2002-01-24
US6696040B2 (en) 2004-02-24
EP1324690A1 (de) 2003-07-09
JP2004515263A (ja) 2004-05-27
US20020037251A1 (en) 2002-03-28

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