AU2001284308A1 - Method of nucleic acid typing or sequencing - Google Patents

Method of nucleic acid typing or sequencing

Info

Publication number
AU2001284308A1
AU2001284308A1 AU2001284308A AU8430801A AU2001284308A1 AU 2001284308 A1 AU2001284308 A1 AU 2001284308A1 AU 2001284308 A AU2001284308 A AU 2001284308A AU 8430801 A AU8430801 A AU 8430801A AU 2001284308 A1 AU2001284308 A1 AU 2001284308A1
Authority
AU
Australia
Prior art keywords
nucleic acid
sequencing
acid molecule
typing
acid typing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284308A
Inventor
Bjorn Ekstrom
Nader Pourmand
Mostafa Ronaghi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotage AB
Leland Stanford Junior University
Original Assignee
Pyrosequencing AB
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pyrosequencing AB, Leland Stanford Junior University filed Critical Pyrosequencing AB
Publication of AU2001284308A1 publication Critical patent/AU2001284308A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Semiconductor Lasers (AREA)

Abstract

The method of the invention relates to a method of typing one or more nucleic acid molecules, said method comprising: simultaneously or sequentially performing two or more primer extension reactions, each primer binding at a different predetermined site in said nucleic acid molecule(s), and determining the pattern of nucleotide incorporation to obtain a test pattern for said nucleic acid molecule(s) which is optionally compared with one or more reference patterns to type the said nucleic acid molecule(s).
AU2001284308A 2000-09-08 2001-09-10 Method of nucleic acid typing or sequencing Abandoned AU2001284308A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0022069.9A GB0022069D0 (en) 2000-09-08 2000-09-08 Method
GB0022069.9 2000-09-08
PCT/GB2001/004042 WO2002020837A2 (en) 2000-09-08 2001-09-10 Method of nucleic acid typing or sequencing

Publications (1)

Publication Number Publication Date
AU2001284308A1 true AU2001284308A1 (en) 2002-03-22

Family

ID=9899101

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284308A Abandoned AU2001284308A1 (en) 2000-09-08 2001-09-10 Method of nucleic acid typing or sequencing

Country Status (10)

Country Link
US (1) US20050084851A1 (en)
EP (1) EP1322782B1 (en)
JP (1) JP4945779B2 (en)
AT (1) ATE415490T1 (en)
AU (1) AU2001284308A1 (en)
CA (1) CA2421857A1 (en)
DE (1) DE60136724D1 (en)
ES (1) ES2317928T3 (en)
GB (1) GB0022069D0 (en)
WO (1) WO2002020837A2 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
JP4603356B2 (en) * 2002-07-26 2010-12-22 アボット・ラボラトリーズ Method for detecting and quantifying hepatitis C virus
AU2003265185A1 (en) * 2002-09-27 2004-04-19 Biotage Ab New sequencing method for sequencing rna molecules
DE602004036672C5 (en) 2003-01-29 2012-11-29 454 Life Sciences Corporation Nucleic acid amplification based on bead emulsion
WO2004090160A1 (en) * 2003-04-11 2004-10-21 Dna Landmarks Inc. Methods for relative quantification of specific nucleic acid sequences
EP1711621A4 (en) 2003-10-28 2008-06-18 Dynal Biotech Llc Primers, methods and kits for amplifying or detecting human leukocyte antigen alleles
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
DE10356783A1 (en) * 2003-12-02 2005-07-07 Universität Zu Köln Method for multiplex sequencing
FR2866349B1 (en) * 2004-02-12 2008-05-16 Biomerieux Sa METHOD FOR DIAGNOSING / PROGNOSING THROMBOSIS
DE602005020421D1 (en) 2004-02-19 2010-05-20 Helicos Biosciences Corp METHOD FOR THE ANALYSIS OF POLYNUCLEOTIDE SEQUENCES
GB0406864D0 (en) * 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
GB0406863D0 (en) * 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
GB0406865D0 (en) * 2004-03-26 2004-04-28 Qiagen Gmbh Nucleic acid sequencing
US7785785B2 (en) 2004-11-12 2010-08-31 The Board Of Trustees Of The Leland Stanford Junior University Charge perturbation detection system for DNA and other molecules
DE602005025072D1 (en) * 2004-11-24 2011-01-13 Immunehealth Screening procedure for homologous recombination events
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
AU2011226792A1 (en) 2010-06-11 2012-01-12 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
WO2012058459A2 (en) 2010-10-27 2012-05-03 Life Technologies Corporation Predictive model for use in sequencing-by-synthesis
US10273540B2 (en) 2010-10-27 2019-04-30 Life Technologies Corporation Methods and apparatuses for estimating parameters in a predictive model for use in sequencing-by-synthesis
WO2012118555A1 (en) 2010-12-29 2012-09-07 Life Technologies Corporation Time-warped background signal for sequencing-by-synthesis operations
EP2658999B1 (en) 2010-12-30 2019-03-13 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
US10241075B2 (en) 2010-12-30 2019-03-26 Life Technologies Corporation Methods, systems, and computer readable media for nucleic acid sequencing
US20130060482A1 (en) 2010-12-30 2013-03-07 Life Technologies Corporation Methods, systems, and computer readable media for making base calls in nucleic acid sequencing
EP3366782B1 (en) 2011-04-08 2021-03-10 Life Technologies Corporation Phase-protecting reagent flow orderings for use in sequencing-by-synthesis
WO2013017702A1 (en) * 2011-08-01 2013-02-07 2B Blackbio S.L. Method for determining the genotype of multiple sequences
US10704164B2 (en) 2011-08-31 2020-07-07 Life Technologies Corporation Methods, systems, computer readable media, and kits for sample identification
US9646132B2 (en) 2012-05-11 2017-05-09 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
US10329608B2 (en) 2012-10-10 2019-06-25 Life Technologies Corporation Methods, systems, and computer readable media for repeat sequencing
US20140296080A1 (en) 2013-03-14 2014-10-02 Life Technologies Corporation Methods, Systems, and Computer Readable Media for Evaluating Variant Likelihood
US9926597B2 (en) 2013-07-26 2018-03-27 Life Technologies Corporation Control nucleic acid sequences for use in sequencing-by-synthesis and methods for designing the same
WO2015051338A1 (en) 2013-10-04 2015-04-09 Life Technologies Corporation Methods and systems for modeling phasing effects in sequencing using termination chemistry
EP2860262A1 (en) * 2013-10-09 2015-04-15 Universität Heidelberg Method for the quantitative analysis of nucleic acid fragmentation and amplifiability
WO2016060974A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, systems, and computer-readable media for accelerated base calling
EP4220645A3 (en) 2015-05-14 2023-11-08 Life Technologies Corporation Barcode sequences, and related systems and methods
US10619205B2 (en) 2016-05-06 2020-04-14 Life Technologies Corporation Combinatorial barcode sequences, and related systems and methods
EP3469102B1 (en) 2016-06-10 2023-01-25 Roche Diagnostics GmbH Compositions and methods for detection of hepatitis c virus genotype 3
CN107841554A (en) * 2017-11-24 2018-03-27 南京艾迪康医学检验所有限公司 Detect the primer, kit and method of Hageman factor (F12) gene mutation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155316C (en) * 1982-04-23 1987-03-11 Sintef PROCEDURE FOR MAKING MAGNETIC POLYMER PARTICLES.
US4863849A (en) * 1985-07-18 1989-09-05 New York Medical College Automatable process for sequencing nucleotide
WO1998029736A1 (en) * 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
GB9901475D0 (en) * 1999-01-22 1999-03-17 Pyrosequencing Ab A method of DNA sequencing
EP2177627B1 (en) * 1999-02-23 2012-05-02 Caliper Life Sciences, Inc. Manipulation of microparticles in microfluidic systems
US20030108867A1 (en) * 1999-04-20 2003-06-12 Chee Mark S Nucleic acid sequencing using microsphere arrays
US20030082549A1 (en) * 2000-08-30 2003-05-01 Xiangjun Liu Method for determining alleles

Also Published As

Publication number Publication date
DE60136724D1 (en) 2009-01-08
ATE415490T1 (en) 2008-12-15
ES2317928T3 (en) 2009-05-01
WO2002020837A2 (en) 2002-03-14
WO2002020837A3 (en) 2003-03-13
JP2004508055A (en) 2004-03-18
CA2421857A1 (en) 2002-03-14
EP1322782A2 (en) 2003-07-02
GB0022069D0 (en) 2000-10-25
US20050084851A1 (en) 2005-04-21
EP1322782B1 (en) 2008-11-26
JP4945779B2 (en) 2012-06-06

Similar Documents

Publication Publication Date Title
AU2001284308A1 (en) Method of nucleic acid typing or sequencing
WO2003027307A3 (en) Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication
DE60127469D1 (en) POTENTIOMETRIC DNA MICROARRAY, METHOD FOR THE PRODUCTION AND METHOD FOR NUCLEIC ACID ANALYSIS
ATE414096T1 (en) METHOD FOR DETECTING AND QUANTIFYING ANALYTES IN COMPLEX MIXTURES
WO2000024937A3 (en) Parallel methods for genomic analysis
WO2007073171A3 (en) Improved strategies for transcript profiling using high throughput sequencing technologies
ATE232880T1 (en) NEW NUCLEOTIDE ANALOGUES
WO1997023650A3 (en) Method for evaluation of polymorphic genetic sequences, and the use thereof in identification of hla types
WO2000077260A8 (en) Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
MY136437A (en) Methods and apparatus for nucleic acid sequencing by signal stretching and data intergration
WO2003040395A3 (en) Universal nucleotides for nucleic acid analysis
AU2496900A (en) Enhanced sequencing by hybridization using pools of probes
DK1013661T3 (en) 2'-O, 4'-methylene bicyclonucleoside
GB0304371D0 (en) DNA Sequence analysis
AU2002365811A1 (en) Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations
WO2003016565A3 (en) Dna sequence analysis
DE60322195D1 (en) PROCESS FOR DETECTING DNA METHYLATION
EP0778351A3 (en) Method of analysis or assay for polynucleotides and analyzer or instrument for polynucleotides
WO2005067648A3 (en) Multiplex spatial profiling of gene expression
ATE368752T1 (en) METHOD FOR DETECTING CYTOSINE METHYLATIONS
DE69815370D1 (en) FLUORESCEND CONJUGATES OF NUCLEOSIDES AND NUCLEOTIDES, THEIR METHOD FOR THE PRODUCTION AND THEIR USE
WO2003014388A3 (en) Method and nucleic acids for the analysis of colon cancer
ATE267879T1 (en) POLYMERASE SIGNAL EXPERIMENT
WO2003078603A3 (en) Strong gene sets for glioma classification
WO2002020833A3 (en) Method for the specific determination of dna -sequences by means of parallel amplification