AU2001278673A1 - Rapidly disintegrating sustained release cefuroxime axetil composition - Google Patents
Rapidly disintegrating sustained release cefuroxime axetil compositionInfo
- Publication number
- AU2001278673A1 AU2001278673A1 AU2001278673A AU7867301A AU2001278673A1 AU 2001278673 A1 AU2001278673 A1 AU 2001278673A1 AU 2001278673 A AU2001278673 A AU 2001278673A AU 7867301 A AU7867301 A AU 7867301A AU 2001278673 A1 AU2001278673 A1 AU 2001278673A1
- Authority
- AU
- Australia
- Prior art keywords
- cefuroxime axetil
- composition
- sustained release
- rapidly disintegrating
- mixtures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A fast disintegrating controlled release oral composition comprising a core material containing cefuroxime axetil present as controlled release form, the cefuroxime axetil being provided with an outer coating of a copolymer selected from aqueous dispersions of enteric methacrylic acid and methacrylic acid esters anionic copolymers having carboxyl group as the functional group or mixtures thereof and an inner coating of a sustained-release copolymer selected from aqueous dispersions of acrylate and methacrylate pH independent copolymers having quaternary ammonium group as a functional group or mixtures thereof, and optionally probenecid. Additionally, the coating composition may contain plasticizers. The composition is suitable for once daily administration.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70204200A | 2000-10-30 | 2000-10-30 | |
US09702042 | 2000-10-30 | ||
PCT/IN2001/000141 WO2002036126A1 (en) | 2000-10-30 | 2001-08-03 | Rapidly disintegrating sustained release cefuroxime axetil composition |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001278673A1 true AU2001278673A1 (en) | 2002-05-15 |
Family
ID=24819640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001278673A Abandoned AU2001278673A1 (en) | 2000-10-30 | 2001-08-03 | Rapidly disintegrating sustained release cefuroxime axetil composition |
Country Status (7)
Country | Link |
---|---|
US (1) | US6932981B2 (en) |
EP (1) | EP1330250B1 (en) |
AT (1) | ATE266407T1 (en) |
AU (1) | AU2001278673A1 (en) |
DE (1) | DE60103299T2 (en) |
ES (1) | ES2220789T3 (en) |
WO (1) | WO2002036126A1 (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US7527807B2 (en) * | 2000-06-21 | 2009-05-05 | Cubist Pharmaceuticals, Inc. | Compositions and methods for increasing the oral absorption of antimicrobials |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
DK1392314T3 (en) * | 2001-05-09 | 2007-03-12 | Bayer Healthcare Ag | Hitherto unknown use of 2- [2-ethoxy-5- (4-methyl-piperazine-1-sulfonyl) -phenyl] -5-methyl-7-propyl-3H-imidazo [5,1-f] [1,2 , 4] triazin-4-one |
DE60204158T2 (en) | 2001-10-05 | 2006-02-02 | SurModics, Inc., Eden Prairie | COATINGS WITH IMMOBILIZED PARTICLES AND USES THEREOF |
DE10232113A1 (en) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Medicinal products containing vardenafil hydrochloride trihydrate |
SE0203778D0 (en) * | 2002-12-09 | 2002-12-09 | Astrazeneca Ab | A new oral immediate release dosage form |
GB0400971D0 (en) * | 2004-01-16 | 2004-02-18 | Sandoz Ag | Pharmaceutical compositions |
TR200606412T2 (en) * | 2004-03-19 | 2007-01-22 | Eczaciba�I �Zg�N K�Myasal �R�Nler San. Ve T�C. A �. | Preparation of lipid-coated cefuroxime axetil |
DE102004023069A1 (en) * | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | New dosage forms of the PDE 5 inhibitor vardenafil |
US7294347B2 (en) * | 2004-06-21 | 2007-11-13 | Council Of Scientific And Industrial Research | Coating compositions for bitterness inhibition |
US7378109B2 (en) * | 2004-12-23 | 2008-05-27 | Council Of Scientific And Industrial Research | Pharmaceutical composition for improving palatability of drugs and process for preparation thereof |
US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
US8481565B2 (en) | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
DE102005001989A1 (en) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenous formulations of PDE inhibitors |
DE102005009241A1 (en) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Dosage forms with controlled bioavailability |
DE102005009240A1 (en) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Dosage forms with improved pharmacokinetic properties |
EA200702221A1 (en) * | 2005-04-12 | 2008-04-28 | Элан Фарма Интернэшнл Лимитед | CONTROLLED SHIPPING COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS CONTAINING CEFALOSPORIN |
DE102005019458A1 (en) * | 2005-04-25 | 2006-10-26 | Grünenthal GmbH | Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan |
US8968781B2 (en) * | 2005-04-29 | 2015-03-03 | Cubist Pharmaceuticals, Inc. | Therapeutic compositions |
BRPI0616633A2 (en) * | 2005-09-29 | 2011-06-28 | Bayer Healthcare Ag | pde inhibitors and combinations thereof for the treatment of urological disorders |
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
WO2007063552A1 (en) * | 2005-12-02 | 2007-06-07 | Lupin Limited | Stable taste masked formulations of cephalosporins |
KR20100029762A (en) * | 2007-06-13 | 2010-03-17 | 바이엘 쉐링 파마 악티엔게젤샤프트 | Pde inhibitors for the treatment of hearing impairment |
IL187159A0 (en) * | 2007-07-03 | 2009-02-11 | Gur Megiddo | Use of metadoxine in relief of alcohol intoxication |
US20120065221A1 (en) | 2009-02-26 | 2012-03-15 | Theraquest Biosciences, Inc. | Extended Release Oral Pharmaceutical Compositions of 3-Hydroxy-N-Methylmorphinan and Method of Use |
US20110097401A1 (en) | 2009-06-12 | 2011-04-28 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
CN104825483B (en) * | 2015-05-26 | 2017-10-13 | 青岛海之星生物科技有限公司 | A kind of probenecid sustained release tablets and preparation method |
CN104856975A (en) * | 2015-05-26 | 2015-08-26 | 青岛海之星生物科技有限公司 | Probenecid slow release capsule and preparation method thereof |
CN104940207A (en) * | 2015-05-26 | 2015-09-30 | 青岛海之星生物科技有限公司 | Cefalexin and probenecid compound sustained-release capsule and preparation method thereof |
US11554112B2 (en) | 2018-06-07 | 2023-01-17 | Herum Therapeutics International Limited | Combinations of β-lactam compounds and probenecid and uses thereof |
AR117510A1 (en) * | 2019-02-13 | 2021-08-11 | Iterum Therapeutics International Ltd | COMBINATIONS OF b-LACTAMA AND PROBENECID AND USES OF THE SAME |
CN111704562A (en) * | 2020-08-07 | 2020-09-25 | 安徽康正康仁药业有限公司 | Freeze-drying process for disc-loaded sterile bulk pharmaceutical chemicals of probenecid |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59257A (en) * | 1979-02-13 | 1983-09-30 | Rech Applications Therap | 6-(n-(cyclic amino-substituted methylene)amino)penicillanates and salts thereof,their production and pharmaceutical compositions containing them |
ZA881301B (en) * | 1987-02-27 | 1989-10-25 | Lilly Co Eli | Sustained release matrix formulations |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
ATE217789T1 (en) * | 1992-06-04 | 2002-06-15 | Smithkline Beecham Corp | PLEASANT TASTING PHARMACEUTICAL COMPOSITIONS |
FR2772615B1 (en) * | 1997-12-23 | 2002-06-14 | Lipha | MULTILAYER TABLET FOR INSTANT RELEASE THEN PROLONGED ACTIVE SUBSTANCES |
JP2002505290A (en) * | 1998-03-03 | 2002-02-19 | ダエウン ファーマシューティカル カンパニー リミテッド | Pharmaceutical composition comprising cefuroxime acetyl that is stable against water absorption |
DE19835823A1 (en) * | 1998-08-10 | 1999-10-07 | Lindopharm Gmbh | Antibiotic composition useful for preparing stable aqueous suspensions |
SK18142001A3 (en) * | 1999-06-11 | 2002-06-04 | Ranbaxy Laboratories Limited | Taste masked matrix composition and method for the production thereof |
-
2001
- 2001-08-03 AU AU2001278673A patent/AU2001278673A1/en not_active Abandoned
- 2001-08-03 DE DE60103299T patent/DE60103299T2/en not_active Expired - Fee Related
- 2001-08-03 ES ES01956758T patent/ES2220789T3/en not_active Expired - Lifetime
- 2001-08-03 AT AT01956758T patent/ATE266407T1/en not_active IP Right Cessation
- 2001-08-03 WO PCT/IN2001/000141 patent/WO2002036126A1/en active IP Right Grant
- 2001-08-03 EP EP01956758A patent/EP1330250B1/en not_active Expired - Lifetime
- 2001-08-13 US US09/928,466 patent/US6932981B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2002036126A1 (en) | 2002-05-10 |
US6932981B2 (en) | 2005-08-23 |
ATE266407T1 (en) | 2004-05-15 |
EP1330250B1 (en) | 2004-05-12 |
DE60103299D1 (en) | 2004-06-17 |
DE60103299T2 (en) | 2005-05-12 |
US20020119195A1 (en) | 2002-08-29 |
ES2220789T3 (en) | 2004-12-16 |
EP1330250A1 (en) | 2003-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001278673A1 (en) | Rapidly disintegrating sustained release cefuroxime axetil composition | |
AU2001266635A1 (en) | Copolymers of ethylene and selected acrylate esters | |
AU3928501A (en) | Multilayer pharmaceutical product for release in the colon | |
AU2508001A (en) | Aqueous dispersions of acrylate modified alkyd resins and use thereof | |
WO2001080826A3 (en) | Taste masking coating composition | |
AU6868994A (en) | Controlled release formulations coated with aqueous dispersions of acrylic polymers | |
AU2002254036A1 (en) | Taste masked pharmaceutical compositions | |
CA2473991A1 (en) | Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor | |
DK1276469T3 (en) | Taste-masking coating composition | |
CA2332922A1 (en) | Enteric coated pharmaceutical composition and method of manufacturing | |
CA2315261A1 (en) | Oral pharmaceutical extended release dosage form | |
EP0704208A3 (en) | Coating and binder compositions for pharmaceutical forms and pharmaceutical forms prepared therewith | |
IL144898A0 (en) | Treatment for dentin sensitivity with aqueous dispersions of hydrophobe-co-hydrophile copolymers | |
UA88056C2 (en) | Once-a-day oxycodone formulations | |
DE69737546D1 (en) | Aqueous pressure-sensitive adhesive compositions of copolymers of vinyl esters of higher carboxylic acids | |
ATE153355T1 (en) | HOLLOW LATEX POLYMER PARTICLES | |
WO2002044290A3 (en) | Aqueous heteropolymer dispersion for manufacturing coatings and process of its production | |
NO983864L (en) | Morphine and diamorphine salts of anionic, non-narcotic analgesics of the substituted carboxyl type | |
EA200300110A1 (en) | COMPOSITION OF ELETRIPTANE AS PARTICLES | |
MXPA04003540A (en) | Use of a copolymer to produce a galenic form containing a peptide or a protein as active agent. | |
ATE195759T1 (en) | PRESSURE SENSITIVE ADHESIVE LATEX COMPOSITIONS | |
AU2003283492A1 (en) | Spheroids, preparation method thereof and pharmaceutical compositions | |
AU6142600A (en) | Controlled release from copolymers of acrylic or methacrylic acid/l-dopa, acrylic or methacrylic acid/l-alpha-methyl dopa, acrylic or methacrylic acid/carbidopaand their combinations | |
HUP0001646A2 (en) | Spray-dried dispersions, processes for their production and use | |
AU2001247267A1 (en) | Process for crosslinking of ehtylene/acrylic ester copolymers |