AU2001266019A1 - 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives - Google Patents

2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives

Info

Publication number
AU2001266019A1
AU2001266019A1 AU2001266019A AU6601901A AU2001266019A1 AU 2001266019 A1 AU2001266019 A1 AU 2001266019A1 AU 2001266019 A AU2001266019 A AU 2001266019A AU 6601901 A AU6601901 A AU 6601901A AU 2001266019 A1 AU2001266019 A1 AU 2001266019A1
Authority
AU
Australia
Prior art keywords
amino
leucyl
tert
hydroxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001266019A
Other languages
English (en)
Inventor
Pascal Furet
Carlos Garcia-Echeverria
Patricia Imbach
Marc Lang
Johann Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2001266019A1 publication Critical patent/AU2001266019A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001266019A 2000-05-25 2001-05-23 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives Abandoned AU2001266019A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0012795.1A GB0012795D0 (en) 2000-05-25 2000-05-25 Organic compounds
GB0012795 2000-05-25
PCT/EP2001/005952 WO2001089282A2 (en) 2000-05-25 2001-05-23 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives

Publications (1)

Publication Number Publication Date
AU2001266019A1 true AU2001266019A1 (en) 2001-12-03

Family

ID=9892401

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001266019A Abandoned AU2001266019A1 (en) 2000-05-25 2001-05-23 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives

Country Status (11)

Country Link
US (2) US20030166572A1 (https=)
EP (1) EP1290012B1 (https=)
JP (1) JP2003533541A (https=)
AT (1) ATE325809T1 (https=)
AU (1) AU2001266019A1 (https=)
CA (1) CA2405871A1 (https=)
DE (1) DE60119514T2 (https=)
ES (1) ES2261422T3 (https=)
GB (1) GB0012795D0 (https=)
PT (1) PT1290012E (https=)
WO (1) WO2001089282A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351738B2 (en) * 2002-11-27 2008-04-01 Elan Pharmaceuticals, Inc. Substituted ureas and carbamates
GB0504950D0 (en) * 2005-03-10 2005-04-20 Novartis Ag Organic compositions
CA2604133C (en) 2005-04-07 2015-12-01 Centre National De La Recherche Scientifique Compounds useful as modulators of the proteasome activity
BRPI0907805A2 (pt) * 2008-02-28 2015-07-14 Novartis Ag Combinações para tratar dor associada à hiv
WO2010096574A1 (en) 2009-02-20 2010-08-26 Lisanti Michael P A method of diagnosis or prognosis of a neoplasm comprising determining the level of expression of a protein in stromal cells adjacent to the neoplasm
GB2523211B (en) 2012-01-27 2020-03-18 Univ Jefferson MCT protein inhibitor-related prognostic and therapeutic methods
WO2014172627A1 (en) 2013-04-19 2014-10-23 Thomas Jefferson University Caveolin-1 related methods for treating glioblastoma with temozolomide
CN112867706B (zh) * 2018-05-29 2024-11-15 奥默罗斯公司 Masp-2抑制剂和使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5538997A (en) * 1993-03-12 1996-07-23 Sandoz Ltd. 2,4-diamino-3-hydroxycarboxylic acid derivatives
EP0982317A1 (en) * 1998-08-26 2000-03-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Bivalent inhibitors of the proteasome
BR0010134A (pt) * 1999-04-27 2002-01-15 Novartis Ag Uso de derivados de ácido 2,4-diamino-3-hidroxicarboxìlico como inibidores de proteassoma

Also Published As

Publication number Publication date
US20060205673A1 (en) 2006-09-14
ES2261422T3 (es) 2006-11-16
DE60119514D1 (de) 2006-06-14
CA2405871A1 (en) 2001-11-29
WO2001089282A3 (en) 2002-05-10
GB0012795D0 (en) 2000-07-19
US20030166572A1 (en) 2003-09-04
EP1290012A2 (en) 2003-03-12
PT1290012E (pt) 2006-09-29
JP2003533541A (ja) 2003-11-11
ATE325809T1 (de) 2006-06-15
EP1290012B1 (en) 2006-05-10
DE60119514T2 (de) 2006-10-05
WO2001089282A2 (en) 2001-11-29

Similar Documents

Publication Publication Date Title
AU2002218167A1 (en) N-phenyl-2-pyrimidine-amine derivatives
WO2003053368A3 (en) Chalcone derivatives and their use to treat diseases
MXPA04000577A (es) Derivados de dolastatina 10.
MY139302A (en) Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
MY139303A (en) Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
MY137039A (en) Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof
PT1416935E (pt) Derivados de 4-amino-6-fenil-pirrolo[2,3-d]pirimidina
GB0114286D0 (en) Nucleoside Derivatives
TW200510325A (en) 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof
MXPA02007942A (es) Derivados de pirrolopirimidinona, procesos de preparacion y uso.
ATE245152T1 (de) Dioxocyclopentylhydroxamsäure
MY135218A (en) 2,6-quinolinyl and 2,6-naphthyl derivatives and their use in the treatment of vla-4 dependent diseases
TW200510392A (en) Chemical compounds
TNSN04203A1 (en) Benzoxazinone-derived compounds, their preparation and use as medicaments
MXPA04004601A (es) Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos.
WO2005037798A3 (en) Amide or thiomide derivatives and their use in the treatment of pain
CY1108871T1 (el) Υποκατεστημενα παραγωγα αμινο-φουραν-2-υλ-οξεικου οξεος και αμινο-θειεν-2-οξεικου οξεος και η χρησιμοποιηση τους για τη θεραπεια ημικρανιας ή πονου
WO2004100865A3 (en) New benzimidazole derivatives
YU87202A (sh) Derivati arilmetilamina koji se koriste kao inhibitori triptaze
MY135850A (en) Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
TW200505452A (en) Chemical compounds
SE9804212D0 (sv) Compounds
MXPA05010020A (es) Derivados de oxamida.
WO2004087700A8 (fr) Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur
AU2001266019A1 (en) 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives