AU2001259961A1 - Method and technology for high-throughput lead profiling - Google Patents
Method and technology for high-throughput lead profilingInfo
- Publication number
- AU2001259961A1 AU2001259961A1 AU2001259961A AU5996101A AU2001259961A1 AU 2001259961 A1 AU2001259961 A1 AU 2001259961A1 AU 2001259961 A AU2001259961 A AU 2001259961A AU 5996101 A AU5996101 A AU 5996101A AU 2001259961 A1 AU2001259961 A1 AU 2001259961A1
- Authority
- AU
- Australia
- Prior art keywords
- technology
- throughput lead
- throughput
- lead profiling
- profiling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
- G01K7/02—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using thermoelectric elements, e.g. thermocouples
- G01K7/028—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using thermoelectric elements, e.g. thermocouples using microstructures, e.g. made of silicon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
- G01N25/48—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation
- G01N25/4846—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample
- G01N25/4866—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample by using a differential method
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Cell Biology (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Blast Furnaces (AREA)
Abstract
The present invention is related to a method for high-throughput lead and the use of microcalorimetric devices therein.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20247500P | 2000-05-08 | 2000-05-08 | |
US60202475 | 2000-05-08 | ||
PCT/BE2001/000080 WO2001085978A2 (en) | 2000-05-08 | 2001-05-08 | Method for high-throughput lead profiling |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001259961A1 true AU2001259961A1 (en) | 2001-11-20 |
Family
ID=22750018
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU59962/01A Abandoned AU5996201A (en) | 2000-05-08 | 2001-05-08 | Microphysiometer |
AU2001259961A Abandoned AU2001259961A1 (en) | 2000-05-08 | 2001-05-08 | Method and technology for high-throughput lead profiling |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU59962/01A Abandoned AU5996201A (en) | 2000-05-08 | 2001-05-08 | Microphysiometer |
Country Status (7)
Country | Link |
---|---|
US (2) | US20040038228A1 (en) |
EP (2) | EP1281067B1 (en) |
JP (2) | JP2003532877A (en) |
AT (2) | ATE352036T1 (en) |
AU (2) | AU5996201A (en) |
DE (2) | DE60126077D1 (en) |
WO (2) | WO2001085901A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10028692C2 (en) * | 2000-06-09 | 2002-06-06 | Micronas Gmbh | Procedure for the investigation of membrane-enclosed biocompartments |
US20040110301A1 (en) * | 2000-11-17 | 2004-06-10 | Neilson Andy C | Apparatus and methods for measuring reaction byproducts |
GB0117376D0 (en) * | 2001-07-17 | 2001-09-05 | Amersham Pharm Biotech Uk Ltd | Thermocouple device |
GR1004040B (en) * | 2001-07-31 | 2002-10-31 | Method for the fabrication of suspended porous silicon microstructures and application in gas sensors | |
US7754492B2 (en) | 2002-04-01 | 2010-07-13 | Palo Alto Research Center Incorporated | Thermal sensing device |
US7141210B2 (en) * | 2002-04-01 | 2006-11-28 | Palo Alto Research Center Incorporated | Apparatus and method for a nanocalorimeter for detecting chemical reactions |
US7473030B2 (en) | 2002-04-01 | 2009-01-06 | Palo Alto Research Center Incorporated | Thermal sensing |
US7473031B2 (en) * | 2002-04-01 | 2009-01-06 | Palo Alto Research Center, Incorporated | Resistive thermal sensing |
US7833800B2 (en) | 2002-04-01 | 2010-11-16 | Palo Alto Research Center Incorporated | Thermal sensing with bridge circuitry |
US7147763B2 (en) * | 2002-04-01 | 2006-12-12 | Palo Alto Research Center Incorporated | Apparatus and method for using electrostatic force to cause fluid movement |
WO2004097373A2 (en) * | 2003-04-28 | 2004-11-11 | Univ Arizona | Thermoelectric biosensor for analytes in a gas |
WO2005003765A1 (en) * | 2003-06-30 | 2005-01-13 | Astrazeneca Ab | Isothermal titration calorimetry assays |
US7276351B2 (en) | 2003-09-10 | 2007-10-02 | Seahorse Bioscience | Method and device for measuring multiple physiological properties of cells |
US8658349B2 (en) | 2006-07-13 | 2014-02-25 | Seahorse Bioscience | Cell analysis apparatus and method |
US7419835B2 (en) * | 2003-11-21 | 2008-09-02 | Palo Alto Research Center Incorporated | Screening for ligand binding at specific target sites |
US7416897B2 (en) * | 2003-11-21 | 2008-08-26 | Palo Alto Research Center Incorporated | Method for high-throughput screening assay sample preparation and analysis |
JP4188287B2 (en) * | 2004-07-15 | 2008-11-26 | 三井金属鉱業株式会社 | Thermal sensor and measuring apparatus using the same |
US20060040338A1 (en) * | 2004-08-18 | 2006-02-23 | Odyssey Thera, Inc. | Pharmacological profiling of drugs with cell-based assays |
US7914735B2 (en) * | 2005-01-18 | 2011-03-29 | Palo Alto Research Center Incorporated | Use of physical barriers to minimize evaporative heat losses |
TWI252920B (en) * | 2005-03-25 | 2006-04-11 | Ind Tech Res Inst | Method of fabricating an integral device of a biochip integrated with micro thermo-electric elements and the apparatus thereof |
EP1872114A2 (en) * | 2005-04-21 | 2008-01-02 | Vivactis NV | Calorimetric measuring device |
EP1785721A1 (en) * | 2005-11-11 | 2007-05-16 | Stratos Bio Ltd. | Microbial, viral and mammalian susceptibility to agents that affect cell growth and metabolism, and mode of action of compounds |
SE530138C2 (en) | 2006-05-30 | 2008-03-11 | Symcel Ab | Device and method for measuring heat flow from at least one sample and vessel unit for placement in said device |
US7632008B2 (en) * | 2007-06-08 | 2009-12-15 | Palo Alto Research Center Incorporated | Ranking fragment types with calorimetry |
DE102008042139A1 (en) * | 2008-09-16 | 2010-03-18 | Robert Bosch Gmbh | Exhaust gas protective layers for high temperature ChemFET exhaust gas sensors |
US8202702B2 (en) | 2008-10-14 | 2012-06-19 | Seahorse Bioscience | Method and device for measuring extracellular acidification and oxygen consumption rate with higher precision |
EP2920292B1 (en) | 2012-11-13 | 2017-01-11 | Agilent Technologies, Inc. | Apparatus and methods for three-dimensional tissue measurements based on controlled media flow |
US9285330B2 (en) | 2013-04-04 | 2016-03-15 | Marquette University | Calorimetric microfluidic sensor |
CN106999926A (en) | 2014-06-02 | 2017-08-01 | 安捷伦科技有限公司 | Single-row microplate system and carrier for analyzing biological specimen |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5104804A (en) * | 1990-06-04 | 1992-04-14 | Molecular Devices Corporation | Cell assay device used in a microphysiometer |
EP0542422A1 (en) * | 1991-11-12 | 1993-05-19 | General Atomics | Multi-well microtiter plate |
US5255976A (en) * | 1992-07-10 | 1993-10-26 | Vertex Pharmaceuticals Incorporated | Temperature gradient calorimeter |
ES2176308T3 (en) * | 1993-10-28 | 2002-12-01 | Houston Advanced Res Ct | POROUS MICROSTRUCTURE DEVICE THAT ALLOWS A FLOW. |
US5965452A (en) * | 1996-07-09 | 1999-10-12 | Nanogen, Inc. | Multiplexed active biologic array |
US5654150A (en) * | 1995-06-07 | 1997-08-05 | President And Fellows Of Harvard College | Method of expression cloning |
US6063637A (en) * | 1995-12-13 | 2000-05-16 | California Institute Of Technology | Sensors for sugars and other metal binding analytes |
EP0883801B1 (en) * | 1996-11-01 | 2004-09-15 | TA Instruments, Inc. | Differential scanning calorimeter |
US5739010A (en) * | 1997-04-16 | 1998-04-14 | Incyte Pharmaceuticals, Inc. | Human transcription factor |
EP0921391A1 (en) * | 1997-12-05 | 1999-06-09 | Interuniversitair Micro-Elektronica Centrum Vzw | A device and a method thermal sensing |
AU3413499A (en) * | 1998-03-27 | 1999-10-18 | Aventis Pharma Deutschland Gmbh | Miniaturized microtiter plate for high throughput screening |
BR9909420A (en) * | 1998-03-31 | 2001-09-25 | Du Pont Pharm Co | Compound, kit, diagnostic or therapeutic metallopharmaceutical composition, ultrasound contrast agent composition, therapeutic radiopharmaceutical composition and diagnostic radiopharmaceutical composition |
ATE270329T1 (en) * | 1998-04-15 | 2004-07-15 | Hiroyoshi Hidaka | METHOD FOR DETERMINING THE GENE OF A TARGET PROTEIN USING A MEDICATION |
US6402369B1 (en) * | 1998-11-03 | 2002-06-11 | Sarnoff Corporation | Arrayable thermal assays |
US6703008B2 (en) * | 1999-03-05 | 2004-03-09 | The Procter & Gamble Company | Aerosol hair spray compositions comprising combinations of silicone-grafted copolymers |
WO2002021125A2 (en) * | 2000-09-05 | 2002-03-14 | The Althexis Company, Inc. | Drug discover employing calorimetric target triage |
-
2001
- 2001-05-08 US US10/276,043 patent/US20040038228A1/en not_active Abandoned
- 2001-05-08 JP JP2001582566A patent/JP2003532877A/en not_active Withdrawn
- 2001-05-08 DE DE60126077T patent/DE60126077D1/en not_active Expired - Lifetime
- 2001-05-08 US US10/276,042 patent/US20040038227A1/en not_active Abandoned
- 2001-05-08 AU AU59962/01A patent/AU5996201A/en not_active Abandoned
- 2001-05-08 JP JP2001582491A patent/JP2003532876A/en not_active Withdrawn
- 2001-05-08 EP EP01933482A patent/EP1281067B1/en not_active Expired - Lifetime
- 2001-05-08 WO PCT/BE2001/000081 patent/WO2001085901A2/en active IP Right Grant
- 2001-05-08 DE DE60133380T patent/DE60133380T2/en not_active Expired - Fee Related
- 2001-05-08 WO PCT/BE2001/000080 patent/WO2001085978A2/en active IP Right Grant
- 2001-05-08 AT AT01933482T patent/ATE352036T1/en not_active IP Right Cessation
- 2001-05-08 AU AU2001259961A patent/AU2001259961A1/en not_active Abandoned
- 2001-05-08 AT AT01933483T patent/ATE390629T1/en not_active IP Right Cessation
- 2001-05-08 EP EP01933483A patent/EP1281068B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1281068B1 (en) | 2008-03-26 |
ATE390629T1 (en) | 2008-04-15 |
EP1281068A2 (en) | 2003-02-05 |
AU5996201A (en) | 2001-11-20 |
WO2001085978A2 (en) | 2001-11-15 |
EP1281067B1 (en) | 2007-01-17 |
WO2001085901A2 (en) | 2001-11-15 |
DE60133380D1 (en) | 2008-05-08 |
DE60133380T2 (en) | 2009-04-02 |
EP1281067A2 (en) | 2003-02-05 |
DE60126077D1 (en) | 2007-03-08 |
WO2001085978A3 (en) | 2002-06-27 |
WO2001085901A3 (en) | 2002-06-06 |
JP2003532876A (en) | 2003-11-05 |
US20040038228A1 (en) | 2004-02-26 |
US20040038227A1 (en) | 2004-02-26 |
ATE352036T1 (en) | 2007-02-15 |
JP2003532877A (en) | 2003-11-05 |
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