AU2001259508A1 - Pain signaling molecules - Google Patents

Pain signaling molecules

Info

Publication number
AU2001259508A1
AU2001259508A1 AU2001259508A AU5950801A AU2001259508A1 AU 2001259508 A1 AU2001259508 A1 AU 2001259508A1 AU 2001259508 A AU2001259508 A AU 2001259508A AU 5950801 A AU5950801 A AU 5950801A AU 2001259508 A1 AU2001259508 A1 AU 2001259508A1
Authority
AU
Australia
Prior art keywords
expressed
signaling molecules
pain signaling
novel
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001259508A
Other languages
English (en)
Inventor
David J Anderson
Xinzhong Dong
Sang-Kyou Han
Melvin Simon
Mark Zylka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology
Original Assignee
California Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/704,707 external-priority patent/US7691604B1/en
Application filed by California Institute of Technology filed Critical California Institute of Technology
Publication of AU2001259508A1 publication Critical patent/AU2001259508A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001259508A 2000-05-04 2001-05-04 Pain signaling molecules Abandoned AU2001259508A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US20202700P 2000-05-04 2000-05-04
US60202027 2000-05-04
US22234400P 2000-08-01 2000-08-01
US60222344 2000-08-01
US09/704,707 US7691604B1 (en) 2000-05-04 2000-11-03 MRG polypeptides and nucleic acids encoding the same
US09704707 2000-11-03
US28549301P 2001-04-19 2001-04-19
US60285493 2001-04-19
PCT/US2001/014519 WO2001083555A2 (en) 2000-05-04 2001-05-04 Pain signaling molecules

Publications (1)

Publication Number Publication Date
AU2001259508A1 true AU2001259508A1 (en) 2001-11-12

Family

ID=27498450

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001259508A Abandoned AU2001259508A1 (en) 2000-05-04 2001-05-04 Pain signaling molecules

Country Status (7)

Country Link
EP (1) EP1280904B1 (cg-RX-API-DMAC7.html)
JP (1) JP2003533188A (cg-RX-API-DMAC7.html)
AT (1) ATE312919T1 (cg-RX-API-DMAC7.html)
AU (1) AU2001259508A1 (cg-RX-API-DMAC7.html)
CA (1) CA2407219A1 (cg-RX-API-DMAC7.html)
DE (1) DE60115878T2 (cg-RX-API-DMAC7.html)
WO (1) WO2001083555A2 (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020064822A1 (en) * 2000-03-13 2002-05-30 Ming-Hui Wei Isolated human G-protein coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
DE60135773D1 (en) 2000-10-17 2008-10-23 Astrazeneca Ab Assays
US20040076951A1 (en) * 2000-10-25 2004-04-22 Ming-Hui Wei Isolated human G-protein coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof
EP1360294A2 (en) * 2001-02-08 2003-11-12 Bayer Aktiengesellschaft Regulation of human dorsal root receptor-like g protein-coupled receptor
DE10225443A1 (de) 2002-06-08 2003-12-18 Aventis Pharma Gmbh Verfahren zur Identifizierung von Agonisten oder Antagonisten für den G-Protein gekoppelten Rezeptor mas like 1
WO2004039972A1 (ja) * 2002-10-29 2004-05-13 Takeda Pharmaceutical Company Limited Hi7t213遺伝子導入動物および新規なhi7t213タンパク質およびそのdna
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
DE10310758A1 (de) * 2003-03-11 2004-09-23 Grünenthal GmbH Identifizierung von schmerzrelevanten Genen der SNSR (Sensory Neuron Specific Receptor)-Familie
WO2005003763A2 (en) * 2003-06-18 2005-01-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mas related g-protein coupled receptor 3 (mrgx3)
EP1689401A1 (en) 2003-10-02 2006-08-16 Elan Pharmaceuticals, Inc. Method for reducing pain
WO2005114208A1 (en) * 2004-05-13 2005-12-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mas-related gene mrgd (mrgd)
WO2006005470A2 (en) * 2004-07-15 2006-01-19 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mas related g-protein coupled receptor e (mrge)
WO2006066599A2 (en) * 2004-12-22 2006-06-29 Rheoscience A/S Mas related g protein coupled receptors as drug targets
CN112266931B (zh) * 2020-10-15 2022-04-29 海湃泰克(北京)生物医药科技有限公司 特异性表达hMRGPRX4的转基因大鼠的构建方法及其应用
CN118956756B (zh) * 2024-09-29 2025-07-25 中国人民解放军空军军医大学 一种痛感受器皮肤类器官芯片及其培养基、构建方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9704836D0 (sv) * 1997-12-22 1997-12-22 Astra Pharma Inc Novel receptor
JP2000023676A (ja) * 1998-07-14 2000-01-25 Asahi Chem Ind Co Ltd 7回膜貫通型受容体蛋白質erg5

Also Published As

Publication number Publication date
DE60115878T2 (de) 2006-08-24
DE60115878D1 (de) 2006-01-19
EP1280904A2 (en) 2003-02-05
WO2001083555A3 (en) 2002-05-02
CA2407219A1 (en) 2001-11-08
ATE312919T1 (de) 2005-12-15
JP2003533188A (ja) 2003-11-11
EP1280904B1 (en) 2005-12-14
WO2001083555A2 (en) 2001-11-08

Similar Documents

Publication Publication Date Title
AU2001259508A1 (en) Pain signaling molecules
IL156380A0 (en) Tir taste receptors and genes encoding same
IL136728A0 (en) Novel g protein-coupled receptor
BG110174A (en) Substituted arylpyrazines
HUP0402496A2 (hu) Módosított polipeptidek
DE60304695D1 (de) 7-ARYLSULFONAMID-2,3,4,5-TETRAHYDRO-1H-BENZOiDöAZEPINE MIT 5-HT6 REZEPTOR AFFINITÄT ZUR BEHANDLUNG VON ZENTRALNERVENSYSTEMERKRANKUNGEN
WO2003092363A3 (en) Transgenic high tryptophan plants
ATE423313T1 (de) Methode zum identifizieren von modulatoren der zelloberflächenmembranrezeptoren,nützlich zur behandlung von krankheiten
WO2002090497A3 (en) Transgenic high tryptophan plants
DE69729730D1 (de) Transgene mäuse, die den leukämie inhibierungsfaktor exprimieren können
WO2003023010A3 (en) Sensory neuron receptors
WO2003104397A3 (en) ANTISENSE MODULATION OF PROTEIN KINASE GR 6 EXPRESSION
DE602005027322D1 (de) Verwendung von antikörpern gegen tweak zur behandlung von schlaganfall
TW200503717A (en) Substituted 1,4-pyrazine derivatives
AU2003237493A1 (en) Methods for treating diseases or conditions with peptide constructs
DE60004473D1 (de) Verwendung von gaba-b rezeptor liganden zur herstellungen von medikamenten zur behandlung von neurodegenerativen erkrankungen
WO2003066852A3 (en) Plant growth modulation by drl1 and other proteins of the elongator complex
AU2002257333A1 (en) Novel treatment of neurodegenerative diseases by altering levels of trkb isoforms and/or trkc isoforms
EP1532446A4 (en) LIGANDS OF G-PROTEIN-COUPLED RECEPTORS AND METHODS
AU2003263988A1 (en) Methods and compositions to treat conditions associated with neovascularization
DE60033562D1 (de) Künstliche promotoren zür protein expression in pflanzen
WO2003045325A3 (en) Dopaminergic stimulatory factor
SE9902763D0 (sv) Novel receptor
ATE396996T1 (de) Selektive d1/d5 rezeptorantagonisten zur behandlung von fettleibigkeit und von zns störungen
MY135649A (en) Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders