AU2001253539B2 - Methods of use of penicillamines for the treatment of conditions resulting from DNA damage - Google Patents

Methods of use of penicillamines for the treatment of conditions resulting from DNA damage Download PDF

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Publication number
AU2001253539B2
AU2001253539B2 AU2001253539A AU2001253539A AU2001253539B2 AU 2001253539 B2 AU2001253539 B2 AU 2001253539B2 AU 2001253539 A AU2001253539 A AU 2001253539A AU 2001253539 A AU2001253539 A AU 2001253539A AU 2001253539 B2 AU2001253539 B2 AU 2001253539B2
Authority
AU
Australia
Prior art keywords
age
reaction
glycation
penicillamine
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001253539A
Other languages
English (en)
Other versions
AU2001253539A1 (en
Inventor
Daniel Cervantes-Laurean
Elaine L. Jacobson
Myron K. Jacobson
Georg T. Wondrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIADYNE Corp
University of Kentucky Research Foundation
Original Assignee
NIADYNE CORP
University of Kentucky Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIADYNE CORP, University of Kentucky Research Foundation filed Critical NIADYNE CORP
Publication of AU2001253539A1 publication Critical patent/AU2001253539A1/en
Application granted granted Critical
Publication of AU2001253539B2 publication Critical patent/AU2001253539B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001253539A 2000-04-14 2001-04-16 Methods of use of penicillamines for the treatment of conditions resulting from DNA damage Ceased AU2001253539B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19721600P 2000-04-14 2000-04-14
US60/197,216 2000-04-14
PCT/US2001/012325 WO2001078718A1 (fr) 2000-04-14 2001-04-16 Utilisation de penicillamines pour le traitement d'etats resultant d'une degradation de l'adn

Publications (2)

Publication Number Publication Date
AU2001253539A1 AU2001253539A1 (en) 2002-01-17
AU2001253539B2 true AU2001253539B2 (en) 2005-08-04

Family

ID=22728499

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001253539A Ceased AU2001253539B2 (en) 2000-04-14 2001-04-16 Methods of use of penicillamines for the treatment of conditions resulting from DNA damage
AU5353901A Pending AU5353901A (en) 2000-04-14 2001-04-16 Methods of use of penicillamines for the treatment of conditions resulting from dna damage

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU5353901A Pending AU5353901A (en) 2000-04-14 2001-04-16 Methods of use of penicillamines for the treatment of conditions resulting from dna damage

Country Status (6)

Country Link
EP (1) EP1274418A4 (fr)
JP (1) JP2003530434A (fr)
CN (1) CN1431898A (fr)
AU (2) AU2001253539B2 (fr)
MX (1) MXPA02010182A (fr)
WO (1) WO2001078718A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7622117B2 (en) * 2002-04-17 2009-11-24 Dynamis Therapeutics, Inc. 3-deoxyglucosone and skin
JP4985214B2 (ja) * 2007-08-20 2012-07-25 ソニー株式会社 レーザーを用いた生体物質検出方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070483A (en) * 1975-06-30 1978-01-24 Sidney Lerman Method of administering a human ocular treating agent and product therefor
US5728373A (en) * 1992-08-26 1998-03-17 Beiersdorf Ag Cosmetic and dermatological sunscreen compositions containing thiols and/or thiol derivates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334617A (en) * 1984-03-19 1994-08-02 The Rockefeller University Amino acids useful as inhibitors of the advanced glycosylation of proteins
JPH1053516A (ja) * 1996-05-20 1998-02-24 Shiseido Co Ltd 抗老化皮膚外用剤及びコラーゲン架橋防止用皮膚外用剤
DE60129008T2 (de) * 2000-04-14 2007-10-11 Niadyne Corp., Tucson Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070483A (en) * 1975-06-30 1978-01-24 Sidney Lerman Method of administering a human ocular treating agent and product therefor
US5728373A (en) * 1992-08-26 1998-03-17 Beiersdorf Ag Cosmetic and dermatological sunscreen compositions containing thiols and/or thiol derivates

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CAPLUS Abstract Number 1988:545412 *
PUBMED ABSTRACT 10576452; Jakus V etal, Life Sci, 1999, 65(18-19), pages 1991-3 *

Also Published As

Publication number Publication date
CN1431898A (zh) 2003-07-23
EP1274418A4 (fr) 2005-02-09
JP2003530434A (ja) 2003-10-14
AU5353901A (en) 2001-10-30
MXPA02010182A (es) 2004-08-19
EP1274418A1 (fr) 2003-01-15
WO2001078718A1 (fr) 2001-10-25

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired