AU2001252120A1 - Chiral ionic liquids - Google Patents

Chiral ionic liquids

Info

Publication number
AU2001252120A1
AU2001252120A1 AU2001252120A AU5212001A AU2001252120A1 AU 2001252120 A1 AU2001252120 A1 AU 2001252120A1 AU 2001252120 A AU2001252120 A AU 2001252120A AU 5212001 A AU5212001 A AU 5212001A AU 2001252120 A1 AU2001252120 A1 AU 2001252120A1
Authority
AU
Australia
Prior art keywords
sup
line
formulae
ionic liquids
chiral ionic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001252120A
Inventor
Carsten Bolm
Andreas Bosmann
Wilhelm Keim
Peter Wasserscheid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solvent Innovation GmbH
Original Assignee
Solvent Innovation GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvent Innovation GmbH filed Critical Solvent Innovation GmbH
Publication of AU2001252120A1 publication Critical patent/AU2001252120A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C215/90—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with quaternised amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to chiral ionic liquids of the general formula <?in-line-formulae description="In-line Formulae" end="lead"?>[A]<SUB>n</SUB><SUP>+</SUP>[Y]<SUP>n-</SUP>,<?in-line-formulae description="In-line Formulae" end="tail"?> whereby n=1 or 2, the anion [Y]<SUP>n-</SUP> is the anion of an organic or inorganic proton acid and the cation [A]<SUP>+</SUP> an optically active organic ammonium cation with up to 50 carbon atoms, at least one chirality center and at least one functional group that can produce a coordination by forming hydrogen bridges or by providing free electron pairs. At least one chirality center is provided with a distance of up to 5 atomic bonds from the functional group. The invention also relates to a method for producing said chiral ionic liquids and to the use thereof in methods for the asymmetric synthesis, the asymmetric catalysis and for separating racemates.
AU2001252120A 2000-01-28 2001-01-29 Chiral ionic liquids Abandoned AU2001252120A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10003708 2000-01-28
DE10003708A DE10003708A1 (en) 2000-01-28 2000-01-28 Novel chiral ionic liquids and methods for their preparation in enantiomerically pure or enantiomerically enriched form
PCT/EP2001/000924 WO2001055060A2 (en) 2000-01-28 2001-01-29 Chiral ionic liquids

Publications (1)

Publication Number Publication Date
AU2001252120A1 true AU2001252120A1 (en) 2001-08-07

Family

ID=7629031

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001252120A Abandoned AU2001252120A1 (en) 2000-01-28 2001-01-29 Chiral ionic liquids

Country Status (6)

Country Link
US (1) US6900313B2 (en)
EP (1) EP1250299B1 (en)
AT (1) ATE292609T1 (en)
AU (1) AU2001252120A1 (en)
DE (2) DE10003708A1 (en)
WO (1) WO2001055060A2 (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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NL1021362C2 (en) * 2001-08-31 2003-08-05 Inst Francais Du Petrole Catalyst and solvent composition and catalyst processes using this composition.
DE10155281A1 (en) * 2001-11-08 2003-06-05 Solvent Innovation Gmbh Process for removing polarizable impurities from hydrocarbons and hydrocarbon mixtures by extraction with ionic liquids
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
DE10247578A1 (en) * 2002-10-13 2004-04-22 Solvent Innovation Gmbh Functionalized ionic liquids obtained by a new, more efficient and low-cost method, used as solvents in catalytic reactions or as extractants, entrainers, wash liquids, heat transfer media, surfactants, modifiers and plasticisers
GB0300595D0 (en) * 2003-01-10 2003-02-12 Univ Cambridge Tech Ionic liquids
CN1805939B (en) * 2003-06-17 2010-10-13 艾尼纳制药公司 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
HUE028976T2 (en) 2003-06-17 2017-02-28 Arena Pharm Inc 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
WO2005042491A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
US20070275949A1 (en) * 2003-10-22 2007-11-29 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2C Receptor Associated Diseases
US7423164B2 (en) * 2003-12-31 2008-09-09 Ut-Battelle, Llc Synthesis of ionic liquids
GB0407908D0 (en) * 2004-04-07 2004-05-12 Univ York Ionic liquids
CN101035523A (en) * 2004-07-09 2007-09-12 西格马-奥利奇有限公司 Optically enhanced chiral ionic liquids
US8168830B2 (en) 2004-07-23 2012-05-01 Sigma-Aldrich Co. Llc High stability diionic liquid salts
CA2574460A1 (en) * 2004-07-23 2006-02-02 Sigma-Aldrich Co. High stability diionic liquid salts
US7737102B2 (en) * 2004-11-01 2010-06-15 The Procter & Gamble Company Ionic liquids derived from functionalized anionic surfactants
US20060090777A1 (en) * 2004-11-01 2006-05-04 Hecht Stacie E Multiphase cleaning compositions having ionic liquid phase
US7939485B2 (en) * 2004-11-01 2011-05-10 The Procter & Gamble Company Benefit agent delivery system comprising ionic liquid
DK1838677T3 (en) 2004-12-21 2010-01-11 Arena Pharm Inc Crystalline forms of (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
SI1833473T1 (en) 2004-12-23 2010-01-29 Arena Pharm Inc 5ht2c receptor modulator compositions and methods of use
US8715521B2 (en) * 2005-02-04 2014-05-06 E I Du Pont De Nemours And Company Absorption cycle utilizing ionic liquid as working fluid
US7638058B2 (en) * 2005-04-07 2009-12-29 Matheson Tri-Gas Fluid storage and purification method and system
GB0519898D0 (en) * 2005-09-30 2005-11-09 Bioniqs Ltd Liquids
US8936719B2 (en) * 2006-03-22 2015-01-20 Ultraclean Fuel Pty Ltd. Process for removing sulphur from liquid hydrocarbons
JP5199997B2 (en) * 2006-04-03 2013-05-15 アリーナ ファーマシューティカルズ， インコーポレイテッド Process for preparing 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and related intermediates
US8357734B2 (en) 2006-11-02 2013-01-22 Georgia-Pacific Consumer Products Lp Creping adhesive with ionic liquid
SG177128A1 (en) * 2006-12-05 2012-01-30 Arena Pharm Inc Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
US7998313B2 (en) * 2006-12-07 2011-08-16 Georgia-Pacific Consumer Products Lp Inflated fibers of regenerated cellulose formed from ionic liquid/cellulose dope and related products
EP1950196A1 (en) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Method for manufacturing ammonium hexafluorphosphates
US8097721B2 (en) * 2007-01-31 2012-01-17 Sigma-Aldrich Co. Llc High stability polyionic liquid salts
US8778689B1 (en) 2007-05-23 2014-07-15 The University Of The West Indies Synthesis and use of chiral ionic liquids
DE102007040333A1 (en) * 2007-08-24 2009-02-26 Rheinisch-Westfälische Technische Hochschule Aachen Catalyst composition for enantioselective hydrogenation of unsaturated compounds, e.g. olefins, comprises a transition metal component, a tropoisomeric or racemic chiral ligand and a chiral ionic liquid
US8822727B2 (en) * 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP2223915A1 (en) 2009-02-25 2010-09-01 Dublin City University Ionic liquid solvents
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
KR20130112848A (en) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. Processes for the preparation of 5-ht2c receptor agonists
CN103347523A (en) 2010-09-01 2013-10-09 艾尼纳制药公司 Administration of lorcaserin to individual with renal impairment
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EP2611782A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
EP3485878A1 (en) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
US9130240B2 (en) 2010-10-12 2015-09-08 Toyota Jidosha Kabushiki Kaisha Ionic liquid, lithium secondary battery electrolyte comprising the ionic liquid, and lithium secondary battery comprising the electrolyte
MY181736A (en) 2012-10-09 2021-01-05 Arena Pharm Inc Method of weight management
JP6389832B2 (en) 2013-03-15 2018-09-12 ウルトラクリーン フューエル ピーティーワイ リミテッド Process for removing sulfur compounds from hydrocarbons
US9441169B2 (en) 2013-03-15 2016-09-13 Ultraclean Fuel Pty Ltd Process for removing sulphur compounds from hydrocarbons
CN113185434B (en) * 2021-04-14 2023-03-21 新疆大学 Synthetic method of diaryl sulfone compound

Also Published As

Publication number Publication date
WO2001055060A2 (en) 2001-08-02
DE50105828D1 (en) 2005-05-12
EP1250299B1 (en) 2005-04-06
US6900313B2 (en) 2005-05-31
EP1250299A2 (en) 2002-10-23
DE10003708A1 (en) 2001-08-02
US20030149264A1 (en) 2003-08-07
WO2001055060A3 (en) 2002-01-31
ATE292609T1 (en) 2005-04-15

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