AU2001239564A1 - Lipid membrane, method for measuring membrane permeability, and method for screening - Google Patents

Lipid membrane, method for measuring membrane permeability, and method for screening

Info

Publication number
AU2001239564A1
AU2001239564A1 AU2001239564A AU3956401A AU2001239564A1 AU 2001239564 A1 AU2001239564 A1 AU 2001239564A1 AU 2001239564 A AU2001239564 A AU 2001239564A AU 3956401 A AU3956401 A AU 3956401A AU 2001239564 A1 AU2001239564 A1 AU 2001239564A1
Authority
AU
Australia
Prior art keywords
membrane
screening
lipid
permeability
measuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001239564A
Inventor
Kiyohiko Sugano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AU2001239564A1 publication Critical patent/AU2001239564A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
    • G01N15/082—Investigating permeability by forcing a fluid through a sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
    • G01N15/082—Investigating permeability by forcing a fluid through a sample
    • G01N15/0826—Investigating permeability by forcing a fluid through a sample and measuring fluid flow rate, i.e. permeation rate or pressure change
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
    • G01N2015/086—Investigating permeability, pore-volume, or surface area of porous materials of films, membranes or pellicules
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Fluid Mechanics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The object of the present invention is to provide a lipid membrane whose permeability to substances is high and strongly correlated with the permeability of biomembranes to drugs and which therefore is suitable for rapid measurement. The present invention provides a membrane comprising an unsaturated C7-C9 hydrocarbon and a lipid.
AU2001239564A 2000-03-23 2001-03-23 Lipid membrane, method for measuring membrane permeability, and method for screening Abandoned AU2001239564A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000-82177 2000-03-23
JP2000082177 2000-03-23
JP2000184973 2000-06-20
JP2000-184973 2000-06-20
PCT/JP2001/002346 WO2001070380A1 (en) 2000-03-23 2001-03-23 Lipid membrane, method for measuring membrane permeability, and method for screening

Publications (1)

Publication Number Publication Date
AU2001239564A1 true AU2001239564A1 (en) 2001-10-03

Family

ID=26588168

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001239564A Abandoned AU2001239564A1 (en) 2000-03-23 2001-03-23 Lipid membrane, method for measuring membrane permeability, and method for screening

Country Status (7)

Country Link
US (1) US6861260B2 (en)
EP (1) EP1266684B1 (en)
JP (1) JP3954847B2 (en)
AT (1) ATE270581T1 (en)
AU (1) AU2001239564A1 (en)
DE (1) DE60104190T2 (en)
WO (1) WO2001070380A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1730516A1 (en) 2004-03-30 2006-12-13 Pfizer Products Incorporated Method and device for evaluation of pharmaceutical compositions
DE102005044071A1 (en) * 2005-09-07 2007-03-08 Nimbus Biotechnologie Gmbh Method for measuring the permeation of a substance through a barrier
US8986781B2 (en) 2005-10-27 2015-03-24 Corning Incorporated Immobilized multi-layer artificial membrane for permeability measurements (PAMPA)
JP5051380B2 (en) * 2008-04-03 2012-10-17 日産化学工業株式会社 Evaluation method and screening method of membrane permeability using artificial membrane
WO2010151609A1 (en) * 2009-06-24 2010-12-29 Photoswitch Biosciences Inc. Photoswitch-enabled ion channel assay system
WO2013067203A1 (en) 2011-11-02 2013-05-10 The Regents Of The University Of California Reprogramming of cellular adhesion
US20170138969A1 (en) * 2014-05-23 2017-05-18 Indian Institute Of Technology Madras System And Method For Measuring Permeability Of Drugs/Toxic/Chemical Compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3107527A1 (en) * 1981-02-27 1982-09-16 Klaus Prof. Dr. 8400 Regensburg Heckmann HYPERFILTRATION MEMBRANES WITH SEPARATING LAYERS FROM MONOMOLECULAR FILMS OF TENSIDES
US4490216A (en) * 1983-02-03 1984-12-25 Molecular Devices Corporation Lipid membrane electroanalytical elements and method of analysis therewith
US4637861A (en) * 1985-12-16 1987-01-20 Allied Corporation Stabilized, lipid membrane-based device and method of analysis
US4962022A (en) * 1986-09-22 1990-10-09 Becton Dickinson And Company Storage and use of liposomes
JPH01307635A (en) * 1988-06-03 1989-12-12 Hamamatsu Photonics Kk Method of evaluating material transmission performance of thin film for testing
US5141751A (en) * 1988-06-29 1992-08-25 Daiichi Pharmaceutical Co., Ltd. Lipid membrane structures
JPH0731871A (en) * 1993-05-18 1995-02-03 Canon Inc Membrane structure
JPH08173780A (en) * 1994-12-26 1996-07-09 Asahi Chem Ind Co Ltd Higher fatty acid esterified porous membrane
JPH1190214A (en) * 1997-09-18 1999-04-06 Tokuyama Corp Preparation of ultrathin film of biosubstance
JP2002527358A (en) * 1998-08-31 2002-08-27 グリフォン サイエンシーズ Lipid matrix assisted chemical ligation method and synthesis of membrane polypeptide
TW427001B (en) * 1998-12-30 2001-03-21 United Microelectronics Corp Manufacturing method of DRAM capacitor

Also Published As

Publication number Publication date
DE60104190D1 (en) 2004-08-12
EP1266684B1 (en) 2004-07-07
WO2001070380A1 (en) 2001-09-27
ATE270581T1 (en) 2004-07-15
EP1266684A4 (en) 2003-06-18
US20030111406A1 (en) 2003-06-19
US6861260B2 (en) 2005-03-01
JP3954847B2 (en) 2007-08-08
EP1266684A1 (en) 2002-12-18
DE60104190T2 (en) 2005-07-21

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