AU2001238651A1 - Pyridine-amidines as modulators of p38 map kinase - Google Patents

Pyridine-amidines as modulators of p38 map kinase

Info

Publication number
AU2001238651A1
AU2001238651A1 AU2001238651A AU3865101A AU2001238651A1 AU 2001238651 A1 AU2001238651 A1 AU 2001238651A1 AU 2001238651 A AU2001238651 A AU 2001238651A AU 3865101 A AU3865101 A AU 3865101A AU 2001238651 A1 AU2001238651 A1 AU 2001238651A1
Authority
AU
Australia
Prior art keywords
amidines
modulators
pyridine
map kinase
kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238651A
Inventor
David J. Morgans Jr.
Dongxu Sun
Silke Thode
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iconix Pharmaceuticals Inc
Original Assignee
Iconix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iconix Pharmaceuticals Inc filed Critical Iconix Pharmaceuticals Inc
Publication of AU2001238651A1 publication Critical patent/AU2001238651A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
AU2001238651A 2000-02-23 2001-02-23 Pyridine-amidines as modulators of p38 map kinase Abandoned AU2001238651A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18436800P 2000-02-23 2000-02-23
US60184368 2000-02-23
PCT/US2001/005769 WO2001062731A1 (en) 2000-02-23 2001-02-23 Pyridine-amidines as modulators of p38 map kinase

Publications (1)

Publication Number Publication Date
AU2001238651A1 true AU2001238651A1 (en) 2001-09-03

Family

ID=22676590

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238651A Abandoned AU2001238651A1 (en) 2000-02-23 2001-02-23 Pyridine-amidines as modulators of p38 map kinase

Country Status (5)

Country Link
US (1) US6537996B2 (en)
EP (1) EP1259486A1 (en)
AU (1) AU2001238651A1 (en)
CA (1) CA2401190A1 (en)
WO (1) WO2001062731A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538066A (en) 2002-07-09 2005-12-15 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト Novel pharmaceutical composition using novel anticholinergic agent and p38 kinase inhibitor
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (en) 2004-12-24 2006-10-06 Boehringer Ingelheim Int INDOLINONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY132496A (en) * 1998-05-11 2007-10-31 Vertex Pharma Inhibitors of p38

Also Published As

Publication number Publication date
CA2401190A1 (en) 2001-08-30
US20010044440A1 (en) 2001-11-22
EP1259486A1 (en) 2002-11-27
WO2001062731A1 (en) 2001-08-30
US6537996B2 (en) 2003-03-25

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