AU2001234510A1 - Increasing enantioselectivity in reductions with borane reagents - Google Patents

Increasing enantioselectivity in reductions with borane reagents

Info

Publication number
AU2001234510A1
AU2001234510A1 AU2001234510A AU3451001A AU2001234510A1 AU 2001234510 A1 AU2001234510 A1 AU 2001234510A1 AU 2001234510 A AU2001234510 A AU 2001234510A AU 3451001 A AU3451001 A AU 3451001A AU 2001234510 A1 AU2001234510 A1 AU 2001234510A1
Authority
AU
Australia
Prior art keywords
enantioselectivity
borohydride
borane
increasing
reductions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001234510A
Other languages
English (en)
Inventor
Elizabeth R. Burkhardt
Joseph A. Corella Ii
Karl Matos
Shawn M. Nettles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSA Safety Inc
Original Assignee
Mine Safety Appliances Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mine Safety Appliances Co filed Critical Mine Safety Appliances Co
Publication of AU2001234510A1 publication Critical patent/AU2001234510A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
AU2001234510A 2000-04-20 2001-01-22 Increasing enantioselectivity in reductions with borane reagents Abandoned AU2001234510A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09553264 2000-04-20
US09/553,264 US6218585B1 (en) 2000-04-20 2000-04-20 Increasing enatioselectivity in reductions with borane reagents
PCT/US2001/002069 WO2001081277A1 (fr) 2000-04-20 2001-01-22 Accroissement de l'enantioselectivite dans des reductions au moyen de reactifs au borane

Publications (1)

Publication Number Publication Date
AU2001234510A1 true AU2001234510A1 (en) 2001-11-07

Family

ID=24208775

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001234510A Abandoned AU2001234510A1 (en) 2000-04-20 2001-01-22 Increasing enantioselectivity in reductions with borane reagents

Country Status (7)

Country Link
US (2) US6218585B1 (fr)
EP (1) EP1274666B1 (fr)
AT (1) ATE273258T1 (fr)
AU (1) AU2001234510A1 (fr)
DE (1) DE60104839T2 (fr)
ES (1) ES2223784T3 (fr)
WO (1) WO2001081277A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218585B1 (en) * 2000-04-20 2001-04-17 Mine Safety Appliances Company Increasing enatioselectivity in reductions with borane reagents
FR2824830B1 (fr) * 2001-05-18 2003-07-04 Centre Nat Rech Scient Catalyseur pour reduction enantioselective de cetones
US7767833B2 (en) * 2004-08-12 2010-08-03 Sigma-Aldrich Co. Stabilized borane-tetrahydrofuran complex
US20080200672A1 (en) * 2005-08-30 2008-08-21 Margarita Ortiz-Marciales Highly enantioselective carbonyl reduction with borane catalyzed by chiral spiroborate esters derived from chiral beta-aminoalcohols
US7750168B2 (en) * 2006-02-10 2010-07-06 Sigma-Aldrich Co. Stabilized deuteroborane-tetrahydrofuran complex
MX2008010235A (es) * 2006-02-16 2008-10-23 Kotobuki Pharmaceutical Co Ltd Metodo para producir alcohol opticamente activo.
DE602007008564D1 (en) * 2006-06-26 2010-09-30 Basf Se Boranetherkomplexe
US8013189B2 (en) * 2007-09-21 2011-09-06 Basf Se Accelerated amide and ester reductions with amine boranes and additives
US20100016484A1 (en) * 2008-07-18 2010-01-21 Basf Se Process for producing 1,3,2-dioxaborinane compounds
EP3411359B1 (fr) * 2016-02-04 2021-10-13 Merck Sharp & Dohme Corp. Procédés de préparation de dérivés d'hydroxylamine utiles dans la préparation d'agents anti-infectieux

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US6048985A (en) * 1998-12-22 2000-04-11 Mine Safety Appliances Company Borane-tetrahydrofuran complex method of storing and reacting borane-tetrahydrofuran complex
US6218585B1 (en) * 2000-04-20 2001-04-17 Mine Safety Appliances Company Increasing enatioselectivity in reductions with borane reagents

Also Published As

Publication number Publication date
US6218585B1 (en) 2001-04-17
ES2223784T3 (es) 2005-03-01
US6610894B2 (en) 2003-08-26
DE60104839D1 (de) 2004-09-16
DE60104839T2 (de) 2005-01-05
WO2001081277A1 (fr) 2001-11-01
EP1274666B1 (fr) 2004-08-11
US20010047116A1 (en) 2001-11-29
ATE273258T1 (de) 2004-08-15
EP1274666A1 (fr) 2003-01-15

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