AU2000229045A1 - Benzimidazole derivatives and their use as factor xa inhibitors - Google Patents

Benzimidazole derivatives and their use as factor xa inhibitors

Info

Publication number
AU2000229045A1
AU2000229045A1 AU2000229045A AU2904500A AU2000229045A1 AU 2000229045 A1 AU2000229045 A1 AU 2000229045A1 AU 2000229045 A AU2000229045 A AU 2000229045A AU 2904500 A AU2904500 A AU 2904500A AU 2000229045 A1 AU2000229045 A1 AU 2000229045A1
Authority
AU
Australia
Prior art keywords
inhibitors
factor
benzimidazole derivatives
benzimidazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000229045A
Inventor
Sabine Bernotat-Danielowski
Dr Hans-Peter Buchstaller
Dieter Dorsch
Horst Juraszyk
Werner Mederski
Guido Melzer
Hanns Wurziger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2000229045A1 publication Critical patent/AU2000229045A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2000229045A 2000-01-12 2000-01-12 Benzimidazole derivatives and their use as factor xa inhibitors Abandoned AU2000229045A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2000/000171 WO2001051484A1 (en) 2000-01-12 2000-01-12 Benzimidazole derivatives and their use as factor xa inhibitors

Publications (1)

Publication Number Publication Date
AU2000229045A1 true AU2000229045A1 (en) 2001-07-24

Family

ID=8163791

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000229045A Abandoned AU2000229045A1 (en) 2000-01-12 2000-01-12 Benzimidazole derivatives and their use as factor xa inhibitors

Country Status (2)

Country Link
AU (1) AU2000229045A1 (en)
WO (1) WO2001051484A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007009883A1 (en) 2005-07-15 2007-01-25 F. Hoffmann-La Roche Ag Novel heteroaryl fused cyclic amines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849759A (en) * 1995-12-08 1998-12-15 Berlex Laboratories, Inc. Naphthyl-substituted benzimidazole derivatives as anti-coagulants

Also Published As

Publication number Publication date
WO2001051484A1 (en) 2001-07-19

Similar Documents

Publication Publication Date Title
PT1526132E (en) Substituted oxazolidinone derivatives and their use as factor xa inhibitors
AU2002232439A1 (en) Benzimidazole derivatives useful as tie-2 and/or vegfr-2 inhibitors
AU2001273040A1 (en) Factor xa inhibitors
AU2003301662A1 (en) Quinazolinones and derivatives thereof as factor xa inhibitors
AU2001240542A1 (en) Heterocyclic compounds and their use as parp inhibitors
HK1053124A1 (en) Substituted quinazoline derivatives and their use as inhibitors
AU6762400A (en) Inhibitors of factor xa
AU5283800A (en) Inhibitors of factor xa
AU2001236605A1 (en) Indole and benzimidazole inhibitors of factor xa
AU5283700A (en) Inhibitors of factor xa
AU3034300A (en) Substituted benzimidazoles and their use as parp inhibitors
AU5155500A (en) Inhibitors of factor xa
AU3857300A (en) Inhibitors of factor xa
AU3965900A (en) Cyclo-alkyl substituted benzimidazoles and their use as parp inhibitors
AU2001234705A1 (en) Indalone and benzimidazolone inhibitors of factor xa
AU2002224038A1 (en) Benzimidazole derivatives
AU5283600A (en) Inhibitors of factor xa
AU2003232848A1 (en) Phenylaminopyrimidines and their use as rho-kinase inhibitors
AU2003215756A1 (en) Benzimidazoles and their use as mitogen-activated- and rho-kinase inhibitors
AU2001227122A1 (en) Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof
AU2001249397A1 (en) Oxindole inhibitors of factor xa
IL143987A0 (en) New amidinobenzylamine derivatives and their use as thrombin inhibitors
IL156214A0 (en) New guanidine and amidine derivatives as factor xa inhibitors
IL152396A0 (en) New thiochromane derivatives derivatives and their use as thrombin inhibitors
AU2001276027A1 (en) Heteroaryl-beta-alanine derivatives as alpha 4 integrin inhibitors