AU1719988A - Aminopeptidase for removing n-terminal methionine from proteins and proteins prepared therefrom - Google Patents

Aminopeptidase for removing n-terminal methionine from proteins and proteins prepared therefrom

Info

Publication number
AU1719988A
AU1719988A AU17199/88A AU1719988A AU1719988A AU 1719988 A AU1719988 A AU 1719988A AU 17199/88 A AU17199/88 A AU 17199/88A AU 1719988 A AU1719988 A AU 1719988A AU 1719988 A AU1719988 A AU 1719988A
Authority
AU
Australia
Prior art keywords
proteins
aminopeptidase
prepared therefrom
terminal methionine
proteins prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU17199/88A
Inventor
Gonzola J. Mazzei
Charles G. Miller
Rao Movva
Paul Wingfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV filed Critical Biogen NV
Publication of AU1719988A publication Critical patent/AU1719988A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AU17199/88A 1987-02-10 1988-02-09 Aminopeptidase for removing n-terminal methionine from proteins and proteins prepared therefrom Abandoned AU1719988A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878703015A GB8703015D0 (en) 1987-02-10 1987-02-10 Aminopeptidase
GB8703015 1987-02-10

Publications (1)

Publication Number Publication Date
AU1719988A true AU1719988A (en) 1988-09-14

Family

ID=10612035

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17199/88A Abandoned AU1719988A (en) 1987-02-10 1988-02-09 Aminopeptidase for removing n-terminal methionine from proteins and proteins prepared therefrom

Country Status (4)

Country Link
EP (1) EP0366662A1 (en)
AU (1) AU1719988A (en)
GB (1) GB8703015D0 (en)
WO (1) WO1988005993A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013662A (en) * 1985-09-20 1991-05-07 Cetus Corporation Bacterial methionine n-terminal peptidase
WO1990002195A1 (en) * 1988-08-26 1990-03-08 The General Hospital Corporation Isolation, purification, and characterization of the methionine-specific aminopeptidases: mas i and mas x
AU4221089A (en) * 1988-09-13 1990-04-02 General Hospital Corporation, The Isolation, purification, and characterization of the aminopeptidases: ap2, ap1, and apx
KR900702014A (en) * 1988-09-13 1990-12-05 원본미기재 Isolation, Purification and Characterization of Aminopeptidase AP1 and AP122
WO1990002815A1 (en) * 1988-09-13 1990-03-22 The General Hospital Corporation Isolation, purification, and characterization of the aminopeptidases: mas ii and mas iii
KR970010135B1 (en) * 1993-06-17 1997-06-21 주식회사 엘지화학 Novel aminopeptidase isolated from streptococcus thermonitrificans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE81673T1 (en) * 1984-08-16 1992-11-15 Bio Technology General Corp PROCESS FOR REMOVAL OF NENDAMINOS|UREASE FROM EUKARYOTPOLYPEPTIDE PLANTS AND POLYPEPTIDES THUS PRODUCED.
WO1986007380A1 (en) * 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing polypeptide
US4865974A (en) * 1985-09-20 1989-09-12 Cetus Corporation Bacterial methionine N-terminal peptidase

Also Published As

Publication number Publication date
WO1988005993A3 (en) 1988-11-17
EP0366662A1 (en) 1990-05-09
GB8703015D0 (en) 1987-03-18
WO1988005993A2 (en) 1988-08-25

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