AU1442995A - Novel intermediates for the synthesis of l-aspartyl-d-alpha-aminoalkanoyl-(s)-n-alpha-alkylbenzyl amides useful as artificial sweeteners - Google Patents

Novel intermediates for the synthesis of l-aspartyl-d-alpha-aminoalkanoyl-(s)-n-alpha-alkylbenzyl amides useful as artificial sweeteners

Info

Publication number
AU1442995A
AU1442995A AU14429/95A AU1442995A AU1442995A AU 1442995 A AU1442995 A AU 1442995A AU 14429/95 A AU14429/95 A AU 14429/95A AU 1442995 A AU1442995 A AU 1442995A AU 1442995 A AU1442995 A AU 1442995A
Authority
AU
Australia
Prior art keywords
alpha
aminoalkanoyl
aspartyl
synthesis
artificial sweeteners
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14429/95A
Other languages
English (en)
Inventor
Lihong D'angelo
George A. King
James G. Sweeny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coca Cola Co
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of AU1442995A publication Critical patent/AU1442995A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU14429/95A 1993-12-22 1994-12-22 Novel intermediates for the synthesis of l-aspartyl-d-alpha-aminoalkanoyl-(s)-n-alpha-alkylbenzyl amides useful as artificial sweeteners Abandoned AU1442995A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17199693A 1993-12-22 1993-12-22
US171996 1993-12-22
PCT/US1994/014770 WO1995017418A2 (en) 1993-12-22 1994-12-22 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS

Publications (1)

Publication Number Publication Date
AU1442995A true AU1442995A (en) 1995-07-10

Family

ID=22625935

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14429/95A Abandoned AU1442995A (en) 1993-12-22 1994-12-22 Novel intermediates for the synthesis of l-aspartyl-d-alpha-aminoalkanoyl-(s)-n-alpha-alkylbenzyl amides useful as artificial sweeteners

Country Status (12)

Country Link
EP (1) EP0736037A1 (cs)
JP (1) JPH09507076A (cs)
KR (1) KR970700201A (cs)
AU (1) AU1442995A (cs)
CA (1) CA2179376A1 (cs)
FI (1) FI962592A7 (cs)
IL (1) IL111990A0 (cs)
NO (1) NO962620L (cs)
PE (1) PE25195A1 (cs)
TW (1) TW282450B (cs)
WO (1) WO1995017418A2 (cs)
ZA (1) ZA9410199B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030381A1 (en) * 1995-03-28 1996-10-03 Novo Nordisk A/S Immunosuppressive agents
FR2744454B1 (fr) * 1996-02-07 1998-04-24 Nofre Claude Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant
GB0518667D0 (en) * 2005-09-13 2005-10-19 Univ Reading The Method
US8044173B2 (en) 2005-09-13 2011-10-25 University Of Reading Asymmetric synthesis of peptides
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411925A (en) * 1980-01-21 1983-10-25 Pfizer Inc. Branched amides of L-aspartyl-d-amino acid dipeptides
US4730076A (en) * 1985-12-18 1988-03-08 Nippon Kayaku Kabushiki Kaisha Process for producing α-aspartyl-phenylalanine ester
AT394854B (de) * 1986-06-12 1992-07-10 Biochemie Gmbh Verfahren zur herstellung von n-l-alpha-aspartyl-l-phenylalanin(nieder)alkylestern
ES2077591T3 (es) * 1989-01-26 1995-12-01 Bayer Ag Derivados de acido (met)acrilico opticamente activos, su fabricacion, su polimerizacion para dar polimeros opticamente activos y su uso.
US5286509A (en) * 1992-06-22 1994-02-15 The Coca-Cola Company L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners

Also Published As

Publication number Publication date
FI962592L (fi) 1996-06-20
PE25195A1 (es) 1995-09-29
FI962592A0 (fi) 1996-06-20
WO1995017418A3 (en) 1995-10-19
CA2179376A1 (en) 1995-06-29
NO962620D0 (no) 1996-06-20
IL111990A0 (en) 1995-03-15
ZA9410199B (en) 1995-09-04
JPH09507076A (ja) 1997-07-15
TW282450B (cs) 1996-08-01
WO1995017418A2 (en) 1995-06-29
NO962620L (no) 1996-08-19
KR970700201A (ko) 1997-01-08
FI962592A7 (fi) 1996-06-20
EP0736037A1 (en) 1996-10-09

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