ZA9410199B - Intermediates for the synthesis of L-aspartyl D-alpha-aminoalkanoyl (s)-N-alpha-alkylbenzyl amides useful as artificial sweeteners - Google Patents

Intermediates for the synthesis of L-aspartyl D-alpha-aminoalkanoyl (s)-N-alpha-alkylbenzyl amides useful as artificial sweeteners

Info

Publication number
ZA9410199B
ZA9410199B ZA9410199A ZA9410199A ZA9410199B ZA 9410199 B ZA9410199 B ZA 9410199B ZA 9410199 A ZA9410199 A ZA 9410199A ZA 9410199 A ZA9410199 A ZA 9410199A ZA 9410199 B ZA9410199 B ZA 9410199B
Authority
ZA
South Africa
Prior art keywords
alpha
aminoalkanoyl
aspartyl
intermediates
synthesis
Prior art date
Application number
ZA9410199A
Other languages
English (en)
Inventor
Angelo Lihon L D
James G Sweeny
George A King
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of ZA9410199B publication Critical patent/ZA9410199B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA9410199A 1993-12-22 1994-12-21 Intermediates for the synthesis of L-aspartyl D-alpha-aminoalkanoyl (s)-N-alpha-alkylbenzyl amides useful as artificial sweeteners ZA9410199B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17199693A 1993-12-22 1993-12-22

Publications (1)

Publication Number Publication Date
ZA9410199B true ZA9410199B (en) 1995-09-04

Family

ID=22625935

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9410199A ZA9410199B (en) 1993-12-22 1994-12-21 Intermediates for the synthesis of L-aspartyl D-alpha-aminoalkanoyl (s)-N-alpha-alkylbenzyl amides useful as artificial sweeteners

Country Status (12)

Country Link
EP (1) EP0736037A1 (cs)
JP (1) JPH09507076A (cs)
KR (1) KR970700201A (cs)
AU (1) AU1442995A (cs)
CA (1) CA2179376A1 (cs)
FI (1) FI962592A7 (cs)
IL (1) IL111990A0 (cs)
NO (1) NO962620L (cs)
PE (1) PE25195A1 (cs)
TW (1) TW282450B (cs)
WO (1) WO1995017418A2 (cs)
ZA (1) ZA9410199B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030381A1 (en) * 1995-03-28 1996-10-03 Novo Nordisk A/S Immunosuppressive agents
FR2744454B1 (fr) * 1996-02-07 1998-04-24 Nofre Claude Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant
GB0518667D0 (en) * 2005-09-13 2005-10-19 Univ Reading The Method
US8044173B2 (en) 2005-09-13 2011-10-25 University Of Reading Asymmetric synthesis of peptides
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411925A (en) * 1980-01-21 1983-10-25 Pfizer Inc. Branched amides of L-aspartyl-d-amino acid dipeptides
US4730076A (en) * 1985-12-18 1988-03-08 Nippon Kayaku Kabushiki Kaisha Process for producing α-aspartyl-phenylalanine ester
AT394854B (de) * 1986-06-12 1992-07-10 Biochemie Gmbh Verfahren zur herstellung von n-l-alpha-aspartyl-l-phenylalanin(nieder)alkylestern
ES2077591T3 (es) * 1989-01-26 1995-12-01 Bayer Ag Derivados de acido (met)acrilico opticamente activos, su fabricacion, su polimerizacion para dar polimeros opticamente activos y su uso.
US5286509A (en) * 1992-06-22 1994-02-15 The Coca-Cola Company L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners

Also Published As

Publication number Publication date
FI962592L (fi) 1996-06-20
PE25195A1 (es) 1995-09-29
FI962592A0 (fi) 1996-06-20
WO1995017418A3 (en) 1995-10-19
CA2179376A1 (en) 1995-06-29
NO962620D0 (no) 1996-06-20
IL111990A0 (en) 1995-03-15
JPH09507076A (ja) 1997-07-15
TW282450B (cs) 1996-08-01
WO1995017418A2 (en) 1995-06-29
NO962620L (no) 1996-08-19
KR970700201A (ko) 1997-01-08
FI962592A7 (fi) 1996-06-20
AU1442995A (en) 1995-07-10
EP0736037A1 (en) 1996-10-09

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