ATE98240T1 - Tetrahydropyridinyl substituierte tricyclische derivate mit dopamin antagonistischer wirkung. - Google Patents
Tetrahydropyridinyl substituierte tricyclische derivate mit dopamin antagonistischer wirkung.Info
- Publication number
- ATE98240T1 ATE98240T1 AT91201688T AT91201688T ATE98240T1 AT E98240 T1 ATE98240 T1 AT E98240T1 AT 91201688 T AT91201688 T AT 91201688T AT 91201688 T AT91201688 T AT 91201688T AT E98240 T1 ATE98240 T1 AT E98240T1
- Authority
- AT
- Austria
- Prior art keywords
- disorder
- hydrogen
- lower alkyl
- antagonist action
- dopamine antagonist
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP90308071 | 1990-07-24 | ||
| EP91201688A EP0468562B1 (de) | 1990-07-24 | 1991-07-02 | Tetrahydropyridinyl substituierte tricyclische Derivate mit Dopamin antagonistischer Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE98240T1 true ATE98240T1 (de) | 1993-12-15 |
Family
ID=8205498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91201688T ATE98240T1 (de) | 1990-07-24 | 1991-07-02 | Tetrahydropyridinyl substituierte tricyclische derivate mit dopamin antagonistischer wirkung. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0468562B1 (de) |
| JP (1) | JPH04234384A (de) |
| KR (1) | KR920002595A (de) |
| AT (1) | ATE98240T1 (de) |
| AU (1) | AU640799B2 (de) |
| CA (1) | CA2046488A1 (de) |
| DE (1) | DE69100741T2 (de) |
| ES (1) | ES2062671T3 (de) |
| FI (1) | FI913495A (de) |
| IE (1) | IE912239A1 (de) |
| NZ (1) | NZ239052A (de) |
| PT (1) | PT98421A (de) |
| ZA (1) | ZA915128B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013028999A1 (en) | 2011-08-24 | 2013-02-28 | The Trustees Of Columbia University In The City Of New York | Small molecule inducers of gdnf as potential new therapeutics for neuropsychiatric disorders |
| WO2016086158A1 (en) * | 2014-11-26 | 2016-06-02 | The Trustees Of Columbia University In The City Of New York | Opioid receptor modulators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1184251A (en) * | 1966-04-15 | 1970-03-11 | American Cyanamid Co | Oxazepines and Thiazepines |
| US4221714A (en) * | 1979-08-03 | 1980-09-09 | American Cyanamid Company | 11-(1,2,3,6-Tetrahydro-substituted-4-pyridyl)-dibenz[b,f][1,4]oxazepines |
| US4798841A (en) * | 1987-03-31 | 1989-01-17 | Warner-Lambert Company | Tetrahydropyridine oxime cholinergic agents and method of treatment |
| DE3726908A1 (de) * | 1987-08-13 | 1989-02-23 | Thomae Gmbh Dr K | Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3735895A1 (de) * | 1987-10-23 | 1989-05-03 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1991
- 1991-06-26 IE IE223991A patent/IE912239A1/en unknown
- 1991-07-02 AT AT91201688T patent/ATE98240T1/de not_active IP Right Cessation
- 1991-07-02 DE DE91201688T patent/DE69100741T2/de not_active Expired - Fee Related
- 1991-07-02 ZA ZA915128A patent/ZA915128B/xx unknown
- 1991-07-02 EP EP91201688A patent/EP0468562B1/de not_active Expired - Lifetime
- 1991-07-02 ES ES91201688T patent/ES2062671T3/es not_active Expired - Lifetime
- 1991-07-08 CA CA002046488A patent/CA2046488A1/en not_active Abandoned
- 1991-07-11 AU AU80385/91A patent/AU640799B2/en not_active Ceased
- 1991-07-19 FI FI913495A patent/FI913495A/fi not_active Application Discontinuation
- 1991-07-22 JP JP3181313A patent/JPH04234384A/ja active Pending
- 1991-07-22 NZ NZ239052A patent/NZ239052A/xx unknown
- 1991-07-23 KR KR1019910012570A patent/KR920002595A/ko not_active Application Discontinuation
- 1991-07-23 PT PT98421A patent/PT98421A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0468562B1 (de) | 1993-12-08 |
| AU8038591A (en) | 1992-01-30 |
| ZA915128B (en) | 1992-05-27 |
| AU640799B2 (en) | 1993-09-02 |
| DE69100741T2 (de) | 1994-04-28 |
| JPH04234384A (ja) | 1992-08-24 |
| KR920002595A (ko) | 1992-02-28 |
| ES2062671T3 (es) | 1994-12-16 |
| PT98421A (pt) | 1992-05-29 |
| IE912239A1 (en) | 1992-01-29 |
| FI913495A (fi) | 1992-01-25 |
| CA2046488A1 (en) | 1992-01-25 |
| NZ239052A (en) | 1992-11-25 |
| DE69100741D1 (de) | 1994-01-20 |
| EP0468562A1 (de) | 1992-01-29 |
| FI913495A0 (fi) | 1991-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |