ATE98236T1 - 1-(3-(4-hydroxy-phenyl)-1-hydroxy-1-propyl>-2amino-alkylenoxy-benzen-derivate und deren therapeutische verwendung. - Google Patents
1-(3-(4-hydroxy-phenyl)-1-hydroxy-1-propyl>-2amino-alkylenoxy-benzen-derivate und deren therapeutische verwendung.Info
- Publication number
- ATE98236T1 ATE98236T1 AT89401135T AT89401135T ATE98236T1 AT E98236 T1 ATE98236 T1 AT E98236T1 AT 89401135 T AT89401135 T AT 89401135T AT 89401135 T AT89401135 T AT 89401135T AT E98236 T1 ATE98236 T1 AT E98236T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxy
- alkylenoxy
- 2amino
- propyl
- phenyl
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 3
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8805382 | 1988-04-22 | ||
| EP89401135A EP0338937B1 (de) | 1988-04-22 | 1989-04-21 | 1-[3-(4-Hydroxy-phenyl)-1-hydroxy-1-propyl]-2-amino-alkylenoxy-benzen-Derivate und deren therapeutische Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE98236T1 true ATE98236T1 (de) | 1993-12-15 |
Family
ID=9365590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89401135T ATE98236T1 (de) | 1988-04-22 | 1989-04-21 | 1-(3-(4-hydroxy-phenyl)-1-hydroxy-1-propyl>-2amino-alkylenoxy-benzen-derivate und deren therapeutische verwendung. |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US5017572A (de) |
| EP (1) | EP0338937B1 (de) |
| JP (1) | JPH01311076A (de) |
| AT (1) | ATE98236T1 (de) |
| DE (1) | DE68911193D1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0139296B1 (ko) * | 1988-11-21 | 1998-05-15 | 가와무라 시게꾸니 | 칼콘 유도체 및 그 제조 방법 |
| US5998401A (en) * | 1995-02-28 | 1999-12-07 | Eli Lilly And Company | Naphthyl compounds, intermediates, compositions, and methods |
| US6541479B1 (en) | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
| WO2002072544A2 (en) * | 2001-03-14 | 2002-09-19 | Cytovia, Inc. | Multifluoro-substituted chalcones and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| CA2599331A1 (en) | 2005-02-28 | 2006-09-08 | Meiji Dairies Corporation | Hydroquinone long-chain derivatives and/or phenoxy long-chain derivatives, and pharmaceuticals preparation comprising the same |
| NZ584480A (en) | 2007-10-04 | 2011-08-26 | Bionomics Ltd | Novel aryl potassium channel blockers and uses thereof |
| CA2727780A1 (en) | 2008-06-13 | 2009-12-17 | Bionomics Limited | Novel potassium channel blockers and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3312696A (en) * | 1964-02-20 | 1967-04-04 | Turbanti Luigi | 2-tertiary amino alkoxy-betaphenyl-propiophenones |
| GR78370B (de) * | 1981-12-24 | 1984-09-26 | Delalande Sa | |
| FR2537970B1 (fr) * | 1982-12-15 | 1986-08-14 | Delalande Sa | Nouveaux derives aminoalkoxy aromatiques, leur procede de preparation et leur application en therapeutique |
| FR2518992A1 (fr) * | 1981-12-24 | 1983-07-01 | Delalande Sa | Nouveaux derives aminoalcoxy aromatiques, leur procede de preparation et leur application en therapeutique |
| DE3825559A1 (de) * | 1988-07-28 | 1990-02-01 | Basf Ag | P-hydroxiphenon-derivate und deren anwendung |
-
1989
- 1989-04-18 US US07/339,815 patent/US5017572A/en not_active Expired - Fee Related
- 1989-04-21 EP EP89401135A patent/EP0338937B1/de not_active Expired - Lifetime
- 1989-04-21 AT AT89401135T patent/ATE98236T1/de not_active IP Right Cessation
- 1989-04-21 DE DE89401135T patent/DE68911193D1/de not_active Expired - Lifetime
- 1989-04-21 JP JP1103287A patent/JPH01311076A/ja active Pending
-
1991
- 1991-01-03 US US07/637,075 patent/US5144029A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0338937A2 (de) | 1989-10-25 |
| DE68911193D1 (de) | 1994-01-20 |
| JPH01311076A (ja) | 1989-12-15 |
| EP0338937A3 (en) | 1990-06-27 |
| US5017572A (en) | 1991-05-21 |
| EP0338937B1 (de) | 1993-12-08 |
| US5144029A (en) | 1992-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |