ATE970T1 - HYDROCORTISONESTERS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESSES FOR THEIR MANUFACTURE. - Google Patents

HYDROCORTISONESTERS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESSES FOR THEIR MANUFACTURE.

Info

Publication number
ATE970T1
ATE970T1 AT79103778T AT79103778T ATE970T1 AT E970 T1 ATE970 T1 AT E970T1 AT 79103778 T AT79103778 T AT 79103778T AT 79103778 T AT79103778 T AT 79103778T AT E970 T1 ATE970 T1 AT E970T1
Authority
AT
Austria
Prior art keywords
hydrocortisonesters
manufacture
processes
pharmaceutical preparations
preparations containing
Prior art date
Application number
AT79103778T
Other languages
German (de)
Inventor
Manfred Dr. Baumgarth
Dieter Dr. Orth
Juergen Dr. Harting
Original Assignee
Merck Patent Gesellschaft Mit Beschraenkter Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gesellschaft Mit Beschraenkter Haftung filed Critical Merck Patent Gesellschaft Mit Beschraenkter Haftung
Application granted granted Critical
Publication of ATE970T1 publication Critical patent/ATE970T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Hydrocortisone esters of the formula <IMAGE> wherein R1 is H, formyl or acetyl and R2 is H or CH3 are antiphlogistically active.
AT79103778T 1978-11-08 1979-10-03 HYDROCORTISONESTERS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESSES FOR THEIR MANUFACTURE. ATE970T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782848423 DE2848423A1 (en) 1978-11-08 1978-11-08 HYDROCORTISONESTER, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
EP79103778A EP0011121B1 (en) 1978-11-08 1979-10-03 Hydrocortisone esters, pharmaceutical compositions containing them and process for their preparation

Publications (1)

Publication Number Publication Date
ATE970T1 true ATE970T1 (en) 1982-05-15

Family

ID=6054151

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79103778T ATE970T1 (en) 1978-11-08 1979-10-03 HYDROCORTISONESTERS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESSES FOR THEIR MANUFACTURE.

Country Status (11)

Country Link
US (1) US4264585A (en)
EP (1) EP0011121B1 (en)
JP (1) JPS5569599A (en)
AT (1) ATE970T1 (en)
AU (1) AU531242B2 (en)
CA (1) CA1146534A (en)
DE (2) DE2848423A1 (en)
ES (1) ES485784A1 (en)
HU (1) HU180874B (en)
IL (1) IL58639A (en)
ZA (1) ZA795986B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12237T1 (en) * 1980-12-23 1985-04-15 Schering Ag NEW 6-ALPHA-METHYLHYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND USE.
US4472392A (en) * 1983-01-21 1984-09-18 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids
DE4205934A1 (en) * 1992-02-27 1993-09-02 Basf Ag METHOD FOR PRODUCING FLUOROCHLORINE HYDROCARBON-FREE, LOW-DENSITY POLYURETHANE SOFT FOAMS AND SOFT-ELASTIC POLYURETHANE FOAMS, AND USEFUL THEREOF, WITH URETIFYMETHANE DYPE, WITH POLYURETHANE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2736733A (en) * 1954-01-27 1956-02-28 Merck & Co Inc Hydrocortisone tertiary - butylacetate and processes for preparing the same
US3171846A (en) * 1962-07-10 1965-03-02 Erba Carlo Spa Prednisolone-21-double esters
DE2558076C2 (en) * 1975-12-19 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen Depot steroid esters, processes for their production and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
ZA795986B (en) 1980-10-29
EP0011121B1 (en) 1982-05-05
CA1146534A (en) 1983-05-17
AU531242B2 (en) 1983-08-18
JPS5569599A (en) 1980-05-26
DE2848423A1 (en) 1980-05-29
US4264585A (en) 1981-04-28
DE2962721D1 (en) 1982-06-24
ES485784A1 (en) 1980-05-16
IL58639A0 (en) 1980-02-29
AU5257479A (en) 1980-05-15
HU180874B (en) 1983-04-29
EP0011121A1 (en) 1980-05-28
IL58639A (en) 1983-06-15

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Legal Events

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REN Ceased due to non-payment of the annual fee