SE7901337L - OPTICALLY ACTIVE BENZAMIDE, PREPARED TO PREPARE THIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING ITS - Google Patents
OPTICALLY ACTIVE BENZAMIDE, PREPARED TO PREPARE THIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING ITSInfo
- Publication number
- SE7901337L SE7901337L SE7901337A SE7901337A SE7901337L SE 7901337 L SE7901337 L SE 7901337L SE 7901337 A SE7901337 A SE 7901337A SE 7901337 A SE7901337 A SE 7901337A SE 7901337 L SE7901337 L SE 7901337L
- Authority
- SE
- Sweden
- Prior art keywords
- optically active
- prepare
- prepared
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Natural products OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 2
- BGRJTUBHPOOWDU-NSHDSACASA-N (S)-(-)-sulpiride Chemical compound CCN1CCC[C@H]1CNC(=O)C1=CC(S(N)(=O)=O)=CC=C1OC BGRJTUBHPOOWDU-NSHDSACASA-N 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229960004940 sulpiride Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for the preparation of optically active Sulpiride <IMAGE> starting from levo-proline through the levo N-ethyl-2-pyrrolidino methanol and the levo-N-ethyl-2- aminomethyl-pyrrolidine which is finally reacted with ethyl 2-methoxy-5- sulphoamoyl benzoate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20295/78A IT1095415B (en) | 1978-02-16 | 1978-02-16 | PROCESS FOR THE PRODUCTION OF AN OPTICALLY ACTIVE BENZAMIDE, OPTICALLY ACTIVE BENZAMIDE SO OBTAINED AND COMPOSITIONS |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7901337L true SE7901337L (en) | 1979-08-17 |
SE430888B SE430888B (en) | 1983-12-19 |
Family
ID=11165504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7901337A SE430888B (en) | 1978-02-16 | 1979-02-15 | OPTICALLY ACTIVE LEFT ROTATING N- (1-ETHYL-2-PYRROLIDINYL-METHYL) -2-METOXY-5-SULFAMOYL BENZAMIDE AND PROCEDURE TO PREPARE THIS |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS54130562A (en) |
AT (1) | AT373870B (en) |
CA (1) | CA1097662A (en) |
CH (1) | CH639951A5 (en) |
DE (1) | DE2903891A1 (en) |
DK (1) | DK152752C (en) |
EG (1) | EG14440A (en) |
FR (1) | FR2417498A1 (en) |
GB (1) | GB2014990B (en) |
GR (1) | GR78220B (en) |
IT (1) | IT1095415B (en) |
MX (1) | MX5632E (en) |
NL (1) | NL190845C (en) |
SE (1) | SE430888B (en) |
YU (1) | YU41145B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1141095B (en) * | 1980-11-27 | 1986-10-01 | Ravizza Spa | RESOLUTION PROCESS OF THE SULPYRID RACEMA |
EP0088849A1 (en) * | 1982-03-11 | 1983-09-21 | Choay S.A. | Levorotatory compounds of N-substituted benzenesulphone amides, process for their preparation and pharmaceutical compositions containing them |
SE8602339D0 (en) * | 1986-05-22 | 1986-05-22 | Astra Laekemedel Ab | AND EFFECTIVE STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S) - AND (R) -2-AMINOMETHYLPYRROLIDINES |
DE4103451C2 (en) * | 1991-02-02 | 1994-08-25 | Hormosan Kwizda Gmbh | Uses of the active substance sulpiride in its R or S form |
WO2003055857A1 (en) * | 2001-12-28 | 2003-07-10 | Farmaceutsko-Hemijska Industrija 'zdravlje' | A process for synthesis of heterocyclic aminoalkyl benzamides |
ITMI20051943A1 (en) * | 2005-10-14 | 2007-04-15 | Procos Spa | ANANTIOMERIC RESOLUTION PROCESS OF 2-AMINOMETHYL-PYRROLIDINES 1-SUBSTITUTED FOR DAMAGE IN THE PRESENCE OF LIPASE |
CL2012000874S1 (en) | 2012-01-31 | 2013-03-22 | Saverglass | Bottle with a tapered rectangular parallelepipedic body oriented vertically, with its narrowest part located at the lower end, it has all its curved edges, at its upper end it forms a rectangular surface with convex sides, which is joined to the bottle neck by means of slight slopes. |
CN103772256B (en) * | 2012-10-24 | 2017-10-10 | 江苏天士力帝益药业有限公司 | A kind of preparation method of high-purity Sulpiride or its optical isomer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3891671A (en) * | 1968-08-01 | 1975-06-24 | Ile De France | N-(2-pyrrolidyl or piperidyl alkyl)-4-hydroxy benzamides |
CH605793A5 (en) * | 1974-03-05 | 1978-10-13 | Ile De France | |
FR2394529A2 (en) * | 1977-06-13 | 1979-01-12 | Synthelabo | 2-METHOXY BENZAMIDES AND THEIR THERAPEUTIC APPLICATION |
FR2393794A2 (en) * | 1977-06-06 | 1979-01-05 | Synthelabo | Therapeutic 2-methoxy benzamido methyl heterocycle(s) prepn. - from 2-methoxy benzoic ester(s) and amino methyl heterocycle(s) |
IL52645A (en) * | 1976-08-05 | 1980-02-29 | Synthelabo | Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides |
JPS5365875A (en) * | 1976-11-24 | 1978-06-12 | Teijin Ltd | Preparation of benzenesulfone amide derivs. |
-
1978
- 1978-02-16 IT IT20295/78A patent/IT1095415B/en active
-
1979
- 1979-02-01 DE DE19792903891 patent/DE2903891A1/en active Granted
- 1979-02-05 GB GB7903902A patent/GB2014990B/en not_active Expired
- 1979-02-08 FR FR7903216A patent/FR2417498A1/en active Granted
- 1979-02-12 YU YU308/79A patent/YU41145B/en unknown
- 1979-02-13 AT AT0110179A patent/AT373870B/en not_active IP Right Cessation
- 1979-02-13 MX MX797713U patent/MX5632E/en unknown
- 1979-02-13 JP JP1441979A patent/JPS54130562A/en active Pending
- 1979-02-14 CH CH142779A patent/CH639951A5/en not_active IP Right Cessation
- 1979-02-14 EG EG97/79A patent/EG14440A/en active
- 1979-02-15 SE SE7901337A patent/SE430888B/en not_active IP Right Cessation
- 1979-02-15 GR GR58375A patent/GR78220B/el unknown
- 1979-02-15 DK DK066579A patent/DK152752C/en not_active IP Right Cessation
- 1979-02-16 CA CA321,673A patent/CA1097662A/en not_active Expired
- 1979-02-16 NL NL7901251A patent/NL190845C/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EG14440A (en) | 1984-03-31 |
CH639951A5 (en) | 1983-12-15 |
YU30879A (en) | 1983-02-28 |
GB2014990A (en) | 1979-09-05 |
ATA110179A (en) | 1983-07-15 |
JPS54130562A (en) | 1979-10-09 |
GR78220B (en) | 1984-09-26 |
NL190845C (en) | 1994-09-16 |
NL7901251A (en) | 1979-08-20 |
DK152752C (en) | 1988-09-26 |
IT1095415B (en) | 1985-08-10 |
DE2903891C2 (en) | 1992-02-06 |
MX5632E (en) | 1983-11-15 |
AT373870B (en) | 1984-02-27 |
DK152752B (en) | 1988-05-09 |
FR2417498A1 (en) | 1979-09-14 |
DE2903891A1 (en) | 1979-08-23 |
SE430888B (en) | 1983-12-19 |
YU41145B (en) | 1986-12-31 |
GB2014990B (en) | 1982-06-09 |
IT7820295A0 (en) | 1978-02-16 |
FR2417498B1 (en) | 1983-01-21 |
CA1097662A (en) | 1981-03-17 |
DK66579A (en) | 1979-08-17 |
NL190845B (en) | 1994-04-18 |
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