ATE91152T1 - Gereinigte protein a-zusammensetzungen und verfahren zu ihrer herstellung. - Google Patents
Gereinigte protein a-zusammensetzungen und verfahren zu ihrer herstellung.Info
- Publication number
- ATE91152T1 ATE91152T1 AT89307394T AT89307394T ATE91152T1 AT E91152 T1 ATE91152 T1 AT E91152T1 AT 89307394 T AT89307394 T AT 89307394T AT 89307394 T AT89307394 T AT 89307394T AT E91152 T1 ATE91152 T1 AT E91152T1
- Authority
- AT
- Austria
- Prior art keywords
- purified protein
- compositions
- protein
- manufacture
- processes
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000356 contaminant Substances 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- GUBGYTABKSRVRQ-WFVLMXAXSA-N DEAE-cellulose Chemical compound OC1C(O)C(O)C(CO)O[C@H]1O[C@@H]1C(CO)OC(O)C(O)C1O GUBGYTABKSRVRQ-WFVLMXAXSA-N 0.000 abstract 1
- 101000867232 Escherichia coli Heat-stable enterotoxin II Proteins 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 231100000655 enterotoxin Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22318388A | 1988-07-22 | 1988-07-22 | |
| EP89307394A EP0355047B1 (de) | 1988-07-22 | 1989-07-20 | Gereinigte Protein A-Zusammensetzungen und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE91152T1 true ATE91152T1 (de) | 1993-07-15 |
Family
ID=22835406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89307394T ATE91152T1 (de) | 1988-07-22 | 1989-07-20 | Gereinigte protein a-zusammensetzungen und verfahren zu ihrer herstellung. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5075423A (de) |
| EP (1) | EP0355047B1 (de) |
| JP (1) | JPH02218699A (de) |
| AT (1) | ATE91152T1 (de) |
| CA (1) | CA1339389C (de) |
| DE (1) | DE68907388T2 (de) |
| ES (1) | ES2058538T3 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0289129A3 (de) * | 1987-03-26 | 1990-10-10 | Repligen Corporation | Herstellung von hochgereinigtem Protein A |
| US6042837A (en) * | 1989-09-20 | 2000-03-28 | Kalland; Terje | Methods of staphylococcal enterotoxin directed cell-mediated cytotoxicity (SDCC) |
| US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| US6126945A (en) * | 1989-10-03 | 2000-10-03 | Pharmacia Ab | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| US6197299B1 (en) | 1990-07-20 | 2001-03-06 | Pharmacia & Upjohn Ab | Antibody conjugates |
| SE9402430L (sv) | 1994-07-11 | 1996-01-12 | Pharmacia Ab | Konjugat mellan modifierat superantigen och en målsökande förening samt användning av konjugaten |
| AU699336B2 (en) * | 1995-05-16 | 1998-12-03 | Toray Industries, Inc. | A material for elimination or detoxification of super antigens |
| SE9601245D0 (sv) | 1996-03-29 | 1996-03-29 | Pharmacia Ab | Chimeric superantigens and their use |
| TW517061B (en) | 1996-03-29 | 2003-01-11 | Pharmacia & Amp Upjohn Ab | Modified/chimeric superantigens and their use |
| WO1999010370A1 (en) * | 1997-08-25 | 1999-03-04 | Torres Anthony R | A simple, environmentally benign, method for purifying protein a |
| US6802966B2 (en) * | 2001-08-14 | 2004-10-12 | W. R. Grace & Co. Conn. | Solid compositions for selective adsorption from complex mixtures |
| US6987079B2 (en) * | 2001-08-14 | 2006-01-17 | W.R. Grace & Co.-Conn. | Supported catalyst systems |
| CN101495645B (zh) * | 2005-03-23 | 2012-08-22 | 生物-拉德实验室公司 | 蛋白纯化方法 |
| US20090247421A1 (en) * | 2005-03-23 | 2009-10-01 | Egisto Boschetti | Diverse chemical libraries bound to small particles with paramagnetic properties |
| EP1871726A2 (de) * | 2005-03-23 | 2008-01-02 | Bio-Rad Laboratories, Inc. | Diverse zu kleinen teilchen mit paramagnetischen eigenschaften gebundene chemische archive |
| US7375188B2 (en) * | 2005-07-29 | 2008-05-20 | Mallinckrodt Baker, Inc. | Vegetarian protein a preparation and methods thereof |
| MY185597A (en) * | 2005-09-20 | 2021-05-24 | Avantor Performance Mat Inc | Vegetarian protein a preparation and methods thereof |
| US20080044378A1 (en) * | 2006-05-15 | 2008-02-21 | Introgen Therapeutics, Inc. | Methods and Compositions for Protein Production Using Adenoviral Vectors |
| CA2666053C (en) | 2006-12-06 | 2011-03-29 | Repligen Corporation | Nucleic acids encoding recombinant protein a |
| CN101921320A (zh) * | 2010-07-15 | 2010-12-22 | 大连理工大学 | 一种重组蛋白a的分离纯化方法 |
| CN107312074A (zh) * | 2017-08-31 | 2017-11-03 | 曾庆明 | 一种重组金黄色葡萄球菌b型肠毒素蛋白及应用 |
| CN111902720B (zh) | 2018-03-21 | 2025-02-07 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2322552C2 (de) * | 1972-11-06 | 1986-08-28 | Pharmacia AB, Uppsala | Verfahren zum Abtrennen von Protein A aus Staphylococcus aureus aus einer Flüssigkeit |
| SE8204810L (sv) * | 1982-08-23 | 1984-02-24 | Pharmacia Fine Chemicals Ab | Hybrid-dna-molekyl, transformerad mikroorganism och sett att framstella protein a |
| US5151350A (en) * | 1982-10-27 | 1992-09-29 | Repligen Corporation | Cloned genes encoding recombinant protein a |
| US5089605A (en) * | 1987-03-13 | 1992-02-18 | Repligen Corporation | Immobilized immunoglobulin-binding proteins |
| EP0289129A3 (de) * | 1987-03-26 | 1990-10-10 | Repligen Corporation | Herstellung von hochgereinigtem Protein A |
-
1989
- 1989-07-20 ES ES89307394T patent/ES2058538T3/es not_active Expired - Lifetime
- 1989-07-20 AT AT89307394T patent/ATE91152T1/de not_active IP Right Cessation
- 1989-07-20 DE DE89307394T patent/DE68907388T2/de not_active Expired - Fee Related
- 1989-07-20 EP EP89307394A patent/EP0355047B1/de not_active Expired - Lifetime
- 1989-07-21 JP JP1187587A patent/JPH02218699A/ja active Pending
- 1989-07-21 CA CA000606293A patent/CA1339389C/en not_active Expired - Fee Related
-
1990
- 1990-01-24 US US07/471,014 patent/US5075423A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0355047B1 (de) | 1993-06-30 |
| US5075423A (en) | 1991-12-24 |
| DE68907388D1 (de) | 1993-08-05 |
| EP0355047A1 (de) | 1990-02-21 |
| ES2058538T3 (es) | 1994-11-01 |
| JPH02218699A (ja) | 1990-08-31 |
| DE68907388T2 (de) | 1994-01-05 |
| CA1339389C (en) | 1997-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |