ATE86107T1 - Arginin- und agmatinderivate zur behandlung von protozoen-infektionen. - Google Patents

Arginin- und agmatinderivate zur behandlung von protozoen-infektionen.

Info

Publication number
ATE86107T1
ATE86107T1 AT86117631T AT86117631T ATE86107T1 AT E86107 T1 ATE86107 T1 AT E86107T1 AT 86117631 T AT86117631 T AT 86117631T AT 86117631 T AT86117631 T AT 86117631T AT E86107 T1 ATE86107 T1 AT E86107T1
Authority
AT
Austria
Prior art keywords
arginine
treatment
protozoal infections
agmatine
derivatives
Prior art date
Application number
AT86117631T
Other languages
English (en)
Inventor
Albert Sjoerdsma
Peter P Mccann
Philippe Bey
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE86107T1 publication Critical patent/ATE86107T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
AT86117631T 1985-12-19 1986-12-18 Arginin- und agmatinderivate zur behandlung von protozoen-infektionen. ATE86107T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81114785A 1985-12-19 1985-12-19
EP86117631A EP0228034B1 (de) 1985-12-19 1986-12-18 Arginin- und Agmatinderivate zur Behandlung von Protozoen-Infektionen

Publications (1)

Publication Number Publication Date
ATE86107T1 true ATE86107T1 (de) 1993-03-15

Family

ID=25205700

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86117631T ATE86107T1 (de) 1985-12-19 1986-12-18 Arginin- und agmatinderivate zur behandlung von protozoen-infektionen.

Country Status (5)

Country Link
EP (1) EP0228034B1 (de)
JP (1) JPS62148462A (de)
AT (1) ATE86107T1 (de)
DE (1) DE3687895T2 (de)
ES (1) ES2053434T3 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139563A (en) * 1977-07-01 1979-02-13 Merrell Toraude Et Compagnie α-ACETYLENIC DERIVATIVES OF AMINES
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4134918A (en) * 1977-09-06 1979-01-16 Merrell Toraude Et Compagnie Alpha-halomethyl derivatives of amines
BE881210A (fr) * 1979-04-10 1980-05-16 Merrell Toraude & Co Composition pharmaceutique pour le traitement de l'hypertrophie prostatique benigne et methode d'utilisation de celle-ci
SE460517B (sv) * 1980-06-16 1989-10-23 Merrell Pharma Inc Anvaendning av en foerening foer framstaellning av ett laekemedel foer behandling av infektioner orsakade av trypanosoma brucei
GB2120244B (en) * 1982-05-17 1985-05-01 Merrell Toraude & Co Aminoalkadiene derivative

Also Published As

Publication number Publication date
DE3687895T2 (de) 1993-06-17
EP0228034A3 (en) 1990-05-09
EP0228034A2 (de) 1987-07-08
DE3687895D1 (de) 1993-04-08
JPS62148462A (ja) 1987-07-02
EP0228034B1 (de) 1993-03-03
ES2053434T3 (es) 1994-08-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee