ATE85809T1 - Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns. - Google Patents
Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns.Info
- Publication number
- ATE85809T1 ATE85809T1 AT86200518T AT86200518T ATE85809T1 AT E85809 T1 ATE85809 T1 AT E85809T1 AT 86200518 T AT86200518 T AT 86200518T AT 86200518 T AT86200518 T AT 86200518T AT E85809 T1 ATE85809 T1 AT E85809T1
- Authority
- AT
- Austria
- Prior art keywords
- von willebrand
- sequence
- vwf
- pro
- cdna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8500961A NL8500961A (nl) | 1985-04-01 | 1985-04-01 | Cdna-codering voor de humane von willebrand-factor, plasmiden met een dergelijke cdna-codering respektievelijk fragmenten ervan, alsmede micro-organismen, welke dergelijke plasmiden bevatten. |
EP86200518A EP0197592B1 (de) | 1985-04-01 | 1986-03-26 | Herstellung des menschlichen von-Willebrand-Faktors durch rekombinante DNS |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE85809T1 true ATE85809T1 (de) | 1993-03-15 |
Family
ID=19845776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86200518T ATE85809T1 (de) | 1985-04-01 | 1986-03-26 | Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0197592B1 (de) |
JP (2) | JP3123650B2 (de) |
AT (1) | ATE85809T1 (de) |
CA (1) | CA1341095C (de) |
DE (1) | DE3687761T2 (de) |
NL (1) | NL8500961A (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8597910B1 (en) | 1985-04-11 | 2013-12-03 | Children's Medical Center Corporation | DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells |
JPS62502589A (ja) * | 1985-04-11 | 1987-10-08 | ザ・チヤイルドレンズ・メデイカル・センタ−・コ−ポレ−シヨン | フオン・ビルブラント因子 |
WO1986006745A1 (en) * | 1985-05-16 | 1986-11-20 | Meloy Laboratories, Inc. | MOLECULAR CLONING OF cDNA FOR HUMAN FACTOR VIIIR (VON WILLEBRAND FACTOR) |
US5198349A (en) * | 1986-01-03 | 1993-03-30 | Genetics Institute, Inc. | Method for producing factor VIII:C and analogs |
JP2872255B2 (ja) * | 1987-01-30 | 1999-03-17 | バイオジエン,インコーポレイティド | ファクター▲viii▼の高収量生産法 |
US5849536A (en) * | 1990-03-02 | 1998-12-15 | Bio-Technology General Corp. | Cloning and production of human von willebrand factor GPIb binding domain polypeptides and methods of using same |
US6008193A (en) * | 1990-03-02 | 1999-12-28 | Bio-Technology General Corp. | Methods of using human von Willebrand factor GPIb binding domain polypeptides |
DE4435485C1 (de) * | 1994-10-04 | 1996-03-21 | Immuno Ag | Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor |
DE4435392B4 (de) * | 1994-10-04 | 2008-02-07 | Immuno Ag | Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF |
US6005077A (en) * | 1995-11-10 | 1999-12-21 | Immuno Aktiengesellschaft | Use of von willebrand factor and pharmaceutical formulation |
US6068838A (en) * | 1996-04-29 | 2000-05-30 | Baxter Aktiengesellschaft | Purified multimerase |
US6767707B2 (en) | 1996-07-19 | 2004-07-27 | University Of Michigan | DNA encoding canine von willebrand factor and methods of use |
US6780583B1 (en) | 1996-07-19 | 2004-08-24 | Board Of Trustees Operating Michigan State University | DNA encoding canine von willebrand factor and methods of use |
EP0961836B1 (de) * | 1996-07-19 | 2005-09-21 | The Regents Of The University Of Michigan | Für den von willebrand faktor der hunde kodierende dna und verfahren zu ihrer verwendung |
US6410237B1 (en) | 1997-07-18 | 2002-06-25 | Board Of Trustees Operating Michigan State University | DNA encoding canine von Willebrand factor and methods of use |
AU5134600A (en) * | 1999-05-14 | 2000-12-05 | Incyte Genomics, Inc. | Full-length molecules expressed in human tissues |
CA2579374A1 (en) | 2004-09-07 | 2006-03-30 | Archemix Corp. | Aptamers to von willebrand factor and their use as thrombotic disease therapeutics |
EP2591094B1 (de) | 2010-07-08 | 2018-09-05 | Baxalta GmbH | Verfahren zur herstellung von rekombinantem adamts13 in einer zellkultur |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2079292A (en) * | 1980-07-05 | 1982-01-20 | Speywood Lab Ltd | Blood Clotting Factor Production |
-
1985
- 1985-04-01 NL NL8500961A patent/NL8500961A/nl not_active Application Discontinuation
-
1986
- 1986-03-26 AT AT86200518T patent/ATE85809T1/de not_active IP Right Cessation
- 1986-03-26 DE DE8686200518T patent/DE3687761T2/de not_active Expired - Lifetime
- 1986-03-26 EP EP86200518A patent/EP0197592B1/de not_active Expired - Lifetime
- 1986-03-27 CA CA000505491A patent/CA1341095C/en not_active Expired - Lifetime
- 1986-04-01 JP JP61075408A patent/JP3123650B2/ja not_active Expired - Lifetime
-
2000
- 2000-05-18 JP JP2000145965A patent/JP2000342290A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP3123650B2 (ja) | 2001-01-15 |
JP2000342290A (ja) | 2000-12-12 |
EP0197592B1 (de) | 1993-02-17 |
DE3687761T2 (de) | 1993-06-09 |
JPS6228A (ja) | 1987-01-06 |
DE3687761D1 (de) | 1993-03-25 |
CA1341095C (en) | 2000-09-12 |
NL8500961A (nl) | 1986-11-03 |
EP0197592A1 (de) | 1986-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEIH | Change in the person of patent owner | ||
EELA | Cancelled due to lapse of time |