ATE85809T1 - Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns. - Google Patents

Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns.

Info

Publication number
ATE85809T1
ATE85809T1 AT86200518T AT86200518T ATE85809T1 AT E85809 T1 ATE85809 T1 AT E85809T1 AT 86200518 T AT86200518 T AT 86200518T AT 86200518 T AT86200518 T AT 86200518T AT E85809 T1 ATE85809 T1 AT E85809T1
Authority
AT
Austria
Prior art keywords
von willebrand
sequence
vwf
pro
cdna
Prior art date
Application number
AT86200518T
Other languages
English (en)
Inventor
Hans Pannekoek
Cornelis Lammert Verwey
Paul Johan Diergaarde
Margaretha Hendrika L Hart
Original Assignee
Stichting Vrienden Van De Stic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19845776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE85809(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Stichting Vrienden Van De Stic filed Critical Stichting Vrienden Van De Stic
Application granted granted Critical
Publication of ATE85809T1 publication Critical patent/ATE85809T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT86200518T 1985-04-01 1986-03-26 Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns. ATE85809T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8500961A NL8500961A (nl) 1985-04-01 1985-04-01 Cdna-codering voor de humane von willebrand-factor, plasmiden met een dergelijke cdna-codering respektievelijk fragmenten ervan, alsmede micro-organismen, welke dergelijke plasmiden bevatten.
EP86200518A EP0197592B1 (de) 1985-04-01 1986-03-26 Herstellung des menschlichen von-Willebrand-Faktors durch rekombinante DNS

Publications (1)

Publication Number Publication Date
ATE85809T1 true ATE85809T1 (de) 1993-03-15

Family

ID=19845776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86200518T ATE85809T1 (de) 1985-04-01 1986-03-26 Herstellung des menschlichen von-willebrandfaktors durch rekombinante dns.

Country Status (6)

Country Link
EP (1) EP0197592B1 (de)
JP (2) JP3123650B2 (de)
AT (1) ATE85809T1 (de)
CA (1) CA1341095C (de)
DE (1) DE3687761T2 (de)
NL (1) NL8500961A (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8597910B1 (en) 1985-04-11 2013-12-03 Children's Medical Center Corporation DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells
JPS62502589A (ja) * 1985-04-11 1987-10-08 ザ・チヤイルドレンズ・メデイカル・センタ−・コ−ポレ−シヨン フオン・ビルブラント因子
WO1986006745A1 (en) * 1985-05-16 1986-11-20 Meloy Laboratories, Inc. MOLECULAR CLONING OF cDNA FOR HUMAN FACTOR VIIIR (VON WILLEBRAND FACTOR)
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
JP2872255B2 (ja) * 1987-01-30 1999-03-17 バイオジエン,インコーポレイティド ファクター▲viii▼の高収量生産法
US5849536A (en) * 1990-03-02 1998-12-15 Bio-Technology General Corp. Cloning and production of human von willebrand factor GPIb binding domain polypeptides and methods of using same
US6008193A (en) * 1990-03-02 1999-12-28 Bio-Technology General Corp. Methods of using human von Willebrand factor GPIb binding domain polypeptides
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
DE4435392B4 (de) * 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
US6005077A (en) * 1995-11-10 1999-12-21 Immuno Aktiengesellschaft Use of von willebrand factor and pharmaceutical formulation
US6068838A (en) * 1996-04-29 2000-05-30 Baxter Aktiengesellschaft Purified multimerase
US6767707B2 (en) 1996-07-19 2004-07-27 University Of Michigan DNA encoding canine von willebrand factor and methods of use
US6780583B1 (en) 1996-07-19 2004-08-24 Board Of Trustees Operating Michigan State University DNA encoding canine von willebrand factor and methods of use
EP0961836B1 (de) * 1996-07-19 2005-09-21 The Regents Of The University Of Michigan Für den von willebrand faktor der hunde kodierende dna und verfahren zu ihrer verwendung
US6410237B1 (en) 1997-07-18 2002-06-25 Board Of Trustees Operating Michigan State University DNA encoding canine von Willebrand factor and methods of use
AU5134600A (en) * 1999-05-14 2000-12-05 Incyte Genomics, Inc. Full-length molecules expressed in human tissues
CA2579374A1 (en) 2004-09-07 2006-03-30 Archemix Corp. Aptamers to von willebrand factor and their use as thrombotic disease therapeutics
EP2591094B1 (de) 2010-07-08 2018-09-05 Baxalta GmbH Verfahren zur herstellung von rekombinantem adamts13 in einer zellkultur

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2079292A (en) * 1980-07-05 1982-01-20 Speywood Lab Ltd Blood Clotting Factor Production

Also Published As

Publication number Publication date
JP3123650B2 (ja) 2001-01-15
JP2000342290A (ja) 2000-12-12
EP0197592B1 (de) 1993-02-17
DE3687761T2 (de) 1993-06-09
JPS6228A (ja) 1987-01-06
DE3687761D1 (de) 1993-03-25
CA1341095C (en) 2000-09-12
NL8500961A (nl) 1986-11-03
EP0197592A1 (de) 1986-10-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time